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Shrubby Sophora flavescens root extract powder manufacturer/supplier
As a professional manufacturer deeply rooted in the field of plant extracts, KINTAIBIO®'s shrubby sophora flavescens root extract powder is made from the dried roots of the legume Sophora flavescens. The product utilizes a standardized heated reflux extraction technology to effectively enrich the core active ingredients of the root, followed by vacuum concentration and spray drying to obtain powder with excellent flowability, easy solubility, and convenient storage.
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The core active ingredients of our Sophora flavescens root extract are matrine and oxymatrine, with stable content and high purity. The main specifications are: 40%,70%,95%Total Alkaloids UV;98% Matrine HPLC, 98% Oxymatrine HPLC. In the health field, this extract, with its significant antibacterial and anti-inflammatory properties, has become an important ingredient in the treatment of skin problems such as eczema and dermatitis. Simultaneously, it can promote collagen synthesis and fibroblast proliferation, exhibiting excellent skin anti-aging and moisturizing repair potential. Therefore, it is widely used in high-end skincare and cosmeceutical products to help balance oil production, refine pores, purify the skin, and improve skin health and vitality.
In agricultural applications, our shrubby sophora flavescens root extract powder also performs exceptionally well, serving as a high-quality raw material for green and environmentally friendly biopesticides and functional fertilizers, demonstrating its multi-purpose and sustainable application value. Furthermore, as an important pharmaceutical intermediate, it plays a crucial role in liver disease treatment and anti-tumor drug development.
Botanical Source for making shrubby sophora flavescens root extract powder
Our raw material comes from the dried roots of Sophora flavescens , a deciduous subshrub that grows on sunny slopes, plains, roadsides, sandy soils, and red soils below 1500 meters in altitude. It is distributed throughout China, with significant production in Shanxi, Shaanxi, Hubei, Henan, and Hebei provinces.
We insist on harvesting high-quality cylindrical roots of Sophora flavescens in autumn from various provinces across China, when the roots accumulate the most abundant active ingredients. After carefully removing fibrous roots and impurities and drying, the typical yellowish-white cut surface and strong bitter taste of the root are preserved, directly reflecting its high bioactivity. This lays a solid foundation for subsequent extraction processes, ensuring that the final shrubby Sophora flavescens root extract powder fully reflects its traditional superior value.
COA Of shrubby sophora flavescens root extract powder
How to make shrubby sophora flavescens root extract powder?
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Raw Material Pretreatment
Selected dried Sophora flavescens roots are first washed to remove surface impurities, then pulverized and sieved. This step aims to significantly increase the specific surface area of the raw material, thereby achieving more efficient and complete dissolution of active ingredients in subsequent extraction.
Extraction
We employ a gentle yet efficient dynamic extraction technology, using a 58%-62% (v/v) ethanol-water solution as the solvent. Extraction is carried out at 35-45℃ for 25-35 minutes to maximize the extraction of alkaloids (such as matrine and oxymatrine) and flavonoids from the Sophora flavescens roots.
Concentration
After precision filtration, the extract is transferred to a vacuum concentration system to recover most of the ethanol solvent, yielding a thick paste-like first extract (primary extract). Food-grade ammonia is added to the first extract for alkalization, precisely adjusting the pH to 9-10. After completion, efficient countercurrent extraction is performed at a volume ratio of alkalization solution to extraction solvent chloroform of 1:(0.8~1.2).
Volcanic Concentration
The chloroform layer rich in alkaloids is collected and concentrated again under reduced pressure to completely recover the chloroform, yielding a concentrated second extract (crude alkaloids). The second extract is then deeply purified using an advanced macroporous adsorption resin chromatography system. Through sample loading, adsorption, elution of impurities and target components, the total alkaloids of Sophora flavescens are eluted using a 55%-65% (v/v) ethanol-water solution.
Fine Filtration
The eluent after resin purification undergoes final fine filtration and reduced pressure concentration to form a high-purity extract concentrate. This concentrate is then fed into a spray drying tower for instantaneous high-temperature atomization drying to form Shrubby Sophora Flavescens Root Extract Powder. The spray-dried powder is then vibrated and sieved, and finally sealed and packaged in a GMP cleanroom to protect it from light.
shrubby sophora flavescens root extract powder benefits
shrubby sophora flavescens root extract powder benefits for skin
Recent cutting-edge research has revealed the powerful potential of Shrubby Sophora Flavescens Root Extract Powder in regulating skin immunity and deep anti-inflammatory effects. When the core active ingredients in Sophora flavescens act on the skin through a highly efficient delivery system, they can precisely inhibit key targets closely related to various inflammatory skin diseases (such as psoriasis) and regulate abnormal activation of T lymphocytes.
Source:https://www.sciencedirect.com
This indicates that our high-purity, standardized Sophora flavescens extract not only soothes skin itching and inflammation on the surface but also penetrates deep into the immune regulation process, providing scientific component support for alleviating stubborn symptoms such as psoriasis-like erythema, scaling, and thickened skin, effectively reducing deep tissue inflammatory responses.
shrubby sophora flavescens root extract powder hair growth
Studies have confirmed that the active ingredients in Sophora Flavescens root extract can effectively support the regulation of the hair growth environment and cycle through a multi-target mechanism. Its core function lies in its ability to significantly inhibit the activity of type II 5α-reductase, thereby helping to reduce key factors leading to follicle miniaturization and prolonged resting phase at the source. Simultaneously, it improves the follicle microenvironment from within, providing positive biochemical signals for hair growth and promoting the transition of follicles from the resting phase to the anagen phase.
Source:https://www.sciencedirect.com
Furthermore, its inherent antibacterial and anti-inflammatory properties help maintain the balance of the scalp microecology and alleviate inflammation around the hair follicles, while its effect of promoting local blood circulation delivers richer nutrients to the hair follicles. Our Shrubby Sophora Flavescens Root Extract Powder, used in shampoos, conditioners, and scalp care products, provides rich herbal nutrients to the scalp and hair roots, regulating the hair follicle life cycle and improving the foundation of scalp health.
shrubby sophora flavescens root extract powder eczema
The active ingredients in Sophora flavescens can act on key aspects of skin immune regulation. One of its core mechanisms lies in effectively inhibiting the overactivation of the classic inflammatory signaling pathway TLR4/MyD88/NF-κB, thereby reducing the production and release of key pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) at the source.
Source:https://www.sciencedirect.com
This precise regulation of the inflammatory cascade not only rapidly relieves the superficial symptoms of eczema, such as erythema, swelling, and intense itching, but also intervenes in abnormal immune responses at the molecular level, helping to repair the skin barrier function. Therefore, the highly active Shrubby Sophora Flavescens Root Extract Powder can be used to develop targeted skincare and topical products for eczema, atopic dermatitis, and other related problems.
Reference:https://www.sciencedirect.com/science/article/pii/S2095754825000122
https://www.sciencedirect.com/science/article/abs/pii/S0923181102000609
https://www.sciencedirect.com/science/article/abs/pii/S0378874123014964
shrubby sophora flavescens root extract powder uses
shrubby sophora flavescens root extract powder cream
Shrubby Sophora Flavescens Root Extract Powder is the core active ingredient in Sophora Flavescens Cream. In cosmetic applications, it not only acts as a natural antibacterial and anti-inflammatory agent, effectively inhibiting harmful skin microorganisms and relieving redness and irritation, but also, when incorporated into a face cream formula, it synergistically provides excellent soothing and repairing effects, balances oil production, and strengthens the skin barrier. It is especially suitable for skincare products targeting sensitive, acne-prone, or mildly inflamed skin.
Shrubby Sophora Flavescens Root Extract Powder Supplement
As a potential natural supplement ingredient, Shrubby Sophora Flavescens Root Extract Powder not only helps maintain the body's microbiome balance through its broad-spectrum antibacterial properties, but its unique bitter components also gently stimulate digestion, playing a role in aiding digestion and improving appetite, as traditionally understood.
The alkaloids it contains have been shown to help strengthen the body's defense barrier and regulate immune responses. Therefore, this extract can be innovatively applied to the development of functional dietary supplements for humans, and can also be used as a novel green feed additive.
shrubby sophora flavescens root extract powder side effects
Note: The bioactive components in shrubby sophora flavescens root extract powder, such as matrine, may pose potential risks if used without professional guidance, in excessive doses, or with prolonged improper use.
Based on relevant studies and clinical observations, gastrointestinal discomfort, such as nausea or diarrhea, may occur in rare cases; allergic reactions may occur in a very small number of individuals. Long-term or excessive intake should be monitored for potential liver effects, and pregnant women, breastfeeding women, and individuals with severe underlying liver or kidney disease should avoid use.
We emphasize that as a raw material, the final application of this product must comply with relevant regulations and be developed and used under the evaluation and guidance of professionals to ensure safety. We are committed to providing customers with products of clearly defined ingredients and stable quality, and recommend thorough safety assessments.
Where can I buy Shrubby Sophora Flavescens Root Extract Powder?
Starting with raw material sourcing, we strictly control the quality of Sophora flavescens roots to ensure rich content of effective alkaloids. In production, we adhere to standardized processes and implement a rigorous quality control system. Our products hold GMP, ISO9001:2015, ISO22000:2018, HACCP, and HALAL certifications, guaranteeing that every batch of Shrubby Sophora Flavescens Root Extract Powder possesses high consistency, pure ingredients, and reliable bioactivity.
KINTAIBIO®, with its solid technical foundation and deep market understanding, is committed to providing customers with stable and highly effective Sophora flavescens root extract products, and continuously offers professional technical support and application solutions, working with partners to explore the innovative value of plant extracts in more fields.If you are interested in learning more about our product specifications, samples, or cooperation opportunities, please contact us at sales@kintaibio.com.
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