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Vakerin

Vakerin

Plant Source: The whole plant of Saxifragaceae, rock cabbage, thick leaved rock cabbage, purple gold cow plant, has a hundred liang of gold roots, stems and leaves
Specification: 98%
Test Method: HPLC
CAS Registry No: 477-90-7
Appearance: White powder
Certifications: ISO, HACCP, HALAL, KOSHER, Technical Invention Patent Certificate
MOQ: 1KG
Sample: Free sample available
Production Capacity: 1000KG/month
Delivery Time: Delivery within one day from warehouse
Shelf Life: Three years
Payment: Multiple terms acceptable like T/T, LC, DA
Company Advantage: Kintai mainly focuses on the production of high content plant extracts and pharmaceutical intermediates all the year round
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Product Introduction

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of vakerin in China. Please feel free to wholesale high quality vakerin for sale here from our factory. For price consultation, contact us.

 

1.What is Begenin?

 

Vakerin also known as pyrogallin, also known as cabbage lactone, is a needle-shaped or crystalline powder extracted from the whole plant of Bergenia purpurscens (Hook.f.etThoms.) Engl., a plant of the saxifrage family.
Bergenia purpurascens [scientific name: Bergenia purpurascens (Hook. f. et Thoms.) Engl.] is a perennial herb of the family Saxifragaceae, up to 52 cm in height.  There are also northern Myanmar, northeastern India, northern Bhutan, and Nepal. Born in forests, shrubs, alpine meadows and alpine gravel crevices at an altitude of 2700-4800 meters.
The whole plant contains coumarin such as petogenin. The rhizomes are used as medicine; non-toxic; used to treat weakness, dizziness, overworked cough, hematemesis, hemoptysis, stranguria, leucorrhea and swelling. Use with caution in patients with exogenous fever and physical weakness.

 

Petgenin is an active ingredient of rock cabbage, which has the effect of antitussive and expectorant, and is a "special effect" drug for the treatment of chronic bronchitis, emphysema, bronchial asthma and other respiratory diseases. Tablets, capsules, and granules produced from petracenin have been used in the clinical treatment of chronic bronchitis. For example, the compound bivarin tablets developed by Yunnan Baiyao Group and the Bailing compound bivarin tablets developed by Guizhou Bailing Pharmaceutical Co., Ltd. are all Chinese patent medicines for the treatment of chronic bronchitis. Begenin also has many health benefits, such as scavenging free radicals and inhibiting lipid peroxidation. This effect just fits the popular skin care concepts such as anti-oxidation and scavenging free radicals proposed by the cosmetics industry in recent years. Therefore, many cosmetics manufacturers add rock cabbage as an antioxidant raw material to skin care products.

Vakerin 1

 

Bergenin, also known as pyrogallin, is a needle-like or crystalline powder extracted from the whole plant of Bergenia purpurscens (Hook.f.etThoms.) Engl., a plant of the saxifrage family. Rock cabbage is a newly added variety in the 2015 edition of the Pharmacopoeia. Rock cabbage is mainly produced in Sichuan, Yunnan, Tibet and other places. Harvest in spring and autumn, wash away the sediment, remove the rotten leaves at the root, and dry in the sun.

(1) Intraperitoneal injection and gavage of petracenin have obvious antitussive effects on mice and cats. According to animal experiments, the mechanism of petracenin cough suppression is the inhibition of the central nervous system, but it is different from morphine-based central cough medicines. It suppresses the cough center selectively, but has no obvious enhanced inhibitory effect on other centers.


(2) Brutin has good broad-spectrum antibacterial effect, can inhibit Shigella, Staphylococcus aureus and Pseudomonas aeruginosa, and has antiviral effect; Brutin can promote the recovery of diseased tissues.

 

 

2.Benefits and Application

 

Health benefits

"Bergenin" is an effective ingredient contained in Chinese cabbage, and it is effective for treating respiratory diseases such as chronic bronchitis, emphysema, bronchial asthma. For example, compound bergignin tablets developed by the Yunnan white herbal medicine group and Guizhou centenary pharmaceuticals are traditional Chinese patents and are simple formulations for the treatment of chronic bronchitis.

22Cough

22Analgesia

22Sedation

22Hypnosis

22Anti-inflammatory:It is mainly used clinically to treat chronic bronchitis and chronic gastritis. It is also effective for gastric and duodenal ulcers.

22Liver protection

22Anti-oxidation

22Effects on trachea and lung tissue respiration: It acts on the enzyme system containing the essential group of mercaptocarbamide, which can reduce tissue respiration, but the effect is not strong.

 

Vakerin application

 

Application

22Widely used for various types of pain, gastric and duodenal ulcers, and chronic bronchitis.

Bergenini-Compositae-Tablets

Bergenini Compositae Tablets

 

 

Application in cosmetics

Vakerin has the function of removing free radical activity and inhibiting lipid peroxidation, and there is no toxicity or side effect. This effect is consistent with the concept of popular skin care such as antioxidant and free radical removal proposed by the cosmetics industry in recent years. Therefore, many cosmetics manufacturers add Chinese cabbage to skin care products as antioxidants.

 

 

3.Chemical and Physical Properties

 

CAS Number

477-90-7

Molecular Weight

328.271

Density

1.6±0.1 g/cm3

Boiling Point

658.9±55.0 °C at 760 mmHg

Molecular Formula

C14H16O9

Melting Point

237-240 °C(lit.)

Common Name

Bergenin

Flash Point

250.7±25.0 °C

Vakerin

 

 

Quality Specifications and Standards of Begenin

 

Product name

Begenin

Extract source

The whole plant of Saxifragaceae, rock cabbage, thick leaved rock cabbage, purple gold cow plant, has a hundred liang of gold roots, stems and leaves

Extraction Solvent

Ethyl alcohol

Appearance

White powder

Solubility

Dissolved in methanol, slightly soluble in water or ethanol

Identification

TLC , HPLC

Sulphated Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay of Begenin (HPLC test, percent, Standard in House)

Min. 95.0%

Residual Solvents

 

- N-hexane

NMT 290 PPM

- Methanol

NMT 3000 PPM

- Acetone

NMT 5000 PPM

- Ethyl Acetate

NMT 5000 PPM

- Ethanol

NMT 5000 PPM

Pesticide Residues

 

- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT)

NMT 0.05 PPM

- Aldrin, Endrin, Dieldrin

NMT 0.01 PPM

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China

Shelf life

3 years

 

 

Our advantage

 

Why choose Kintai.jpg

 

 

Our factory

 

Kintai-Factory

 

 

 

Parcel Logistics

 

Packing and shipping

 

 

 

★If you want to get high quality Vakerin , please feel free to contact us at sales@kintaibio.com or feedback in next page.

 

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