Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of vakerin in China. Please feel free to wholesale high quality vakerin for sale here from our factory. For price consultation, contact us.
1.What is Begenin?
Vakerin also known as pyrogallin, also known as cabbage lactone, is a needle-shaped or crystalline powder extracted from the whole plant of Bergenia purpurscens (Hook.f.etThoms.) Engl., a plant of the saxifrage family.
Bergenia purpurascens [scientific name: Bergenia purpurascens (Hook. f. et Thoms.) Engl.] is a perennial herb of the family Saxifragaceae, up to 52 cm in height. There are also northern Myanmar, northeastern India, northern Bhutan, and Nepal. Born in forests, shrubs, alpine meadows and alpine gravel crevices at an altitude of 2700-4800 meters.
The whole plant contains coumarin such as petogenin. The rhizomes are used as medicine; non-toxic; used to treat weakness, dizziness, overworked cough, hematemesis, hemoptysis, stranguria, leucorrhea and swelling. Use with caution in patients with exogenous fever and physical weakness.
Petgenin is an active ingredient of rock cabbage, which has the effect of antitussive and expectorant, and is a "special effect" drug for the treatment of chronic bronchitis, emphysema, bronchial asthma and other respiratory diseases. Tablets, capsules, and granules produced from petracenin have been used in the clinical treatment of chronic bronchitis. For example, the compound bivarin tablets developed by Yunnan Baiyao Group and the Bailing compound bivarin tablets developed by Guizhou Bailing Pharmaceutical Co., Ltd. are all Chinese patent medicines for the treatment of chronic bronchitis. Begenin also has many health benefits, such as scavenging free radicals and inhibiting lipid peroxidation. This effect just fits the popular skin care concepts such as anti-oxidation and scavenging free radicals proposed by the cosmetics industry in recent years. Therefore, many cosmetics manufacturers add rock cabbage as an antioxidant raw material to skin care products.

Bergenin, also known as pyrogallin, is a needle-like or crystalline powder extracted from the whole plant of Bergenia purpurscens (Hook.f.etThoms.) Engl., a plant of the saxifrage family. Rock cabbage is a newly added variety in the 2015 edition of the Pharmacopoeia. Rock cabbage is mainly produced in Sichuan, Yunnan, Tibet and other places. Harvest in spring and autumn, wash away the sediment, remove the rotten leaves at the root, and dry in the sun.
(1) Intraperitoneal injection and gavage of petracenin have obvious antitussive effects on mice and cats. According to animal experiments, the mechanism of petracenin cough suppression is the inhibition of the central nervous system, but it is different from morphine-based central cough medicines. It suppresses the cough center selectively, but has no obvious enhanced inhibitory effect on other centers.
(2) Brutin has good broad-spectrum antibacterial effect, can inhibit Shigella, Staphylococcus aureus and Pseudomonas aeruginosa, and has antiviral effect; Brutin can promote the recovery of diseased tissues.
2.Benefits and Application
Health benefits
"Bergenin" is an effective ingredient contained in Chinese cabbage, and it is effective for treating respiratory diseases such as chronic bronchitis, emphysema, bronchial asthma. For example, compound bergignin tablets developed by the Yunnan white herbal medicine group and Guizhou centenary pharmaceuticals are traditional Chinese patents and are simple formulations for the treatment of chronic bronchitis.
Cough
Analgesia
Sedation
Hypnosis
Anti-inflammatory:It is mainly used clinically to treat chronic bronchitis and chronic gastritis. It is also effective for gastric and duodenal ulcers.
Liver protection
Anti-oxidation
Effects on trachea and lung tissue respiration: It acts on the enzyme system containing the essential group of mercaptocarbamide, which can reduce tissue respiration, but the effect is not strong.

Application
Widely used for various types of pain, gastric and duodenal ulcers, and chronic bronchitis.

Bergenini Compositae Tablets
Application in cosmetics
Vakerin has the function of removing free radical activity and inhibiting lipid peroxidation, and there is no toxicity or side effect. This effect is consistent with the concept of popular skin care such as antioxidant and free radical removal proposed by the cosmetics industry in recent years. Therefore, many cosmetics manufacturers add Chinese cabbage to skin care products as antioxidants.
3.Chemical and Physical Properties
|
CAS Number |
477-90-7 |
Molecular Weight |
328.271 |
|
Density |
1.6±0.1 g/cm3 |
Boiling Point |
658.9±55.0 °C at 760 mmHg |
|
Molecular Formula |
C14H16O9 |
Melting Point |
237-240 °C(lit.) |
|
Common Name |
Bergenin |
Flash Point |
250.7±25.0 °C |

Quality Specifications and Standards of Begenin
|
Product name |
Begenin |
|
Extract source |
The whole plant of Saxifragaceae, rock cabbage, thick leaved rock cabbage, purple gold cow plant, has a hundred liang of gold roots, stems and leaves |
|
Extraction Solvent |
Ethyl alcohol |
|
Appearance |
White powder |
|
Solubility |
Dissolved in methanol, slightly soluble in water or ethanol |
|
Identification |
TLC , HPLC |
|
Sulphated Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of Begenin (HPLC test, percent, Standard in House) |
Min. 95.0% |
|
Residual Solvents |
|
|
- N-hexane |
NMT 290 PPM |
|
- Methanol |
NMT 3000 PPM |
|
- Acetone |
NMT 5000 PPM |
|
- Ethyl Acetate |
NMT 5000 PPM |
|
- Ethanol |
NMT 5000 PPM |
|
Pesticide Residues |
|
|
- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT) |
NMT 0.05 PPM |
|
- Aldrin, Endrin, Dieldrin |
NMT 0.01 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China |
|
Shelf life |
3 years |
Our advantage

Our factory

Parcel Logistics

★If you want to get high quality Vakerin , please feel free to contact us at sales@kintaibio.com or feedback in next page.
Hot Tags: vakerin, China vakerin manufacturers, suppliers, factory, Pure Beta Sitosterol, Osthole Powder, Carnosic Acid Powder, D-(+)-chiro-Inositol powder, Esculin Hydrate, L-carnosine powder








