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Sinomenine Hydrochloride

Sinomenine Hydrochloride

Plant Source:Roots and Stems of Sinomenine
Specification:98% Sinomenine Hydrochloride
Test Method:HPLC
CAS Registry No:6080-33-7
Appearance:White powder
Certifications:ISO, HACCP, HALAL, KOSHER, Technical Invention Patent Certificate
MOQ:1KG
Sample:Free sample available
Production Capacity:1000KG/month
Delivery Time:Delivery within one day from warehouse
Shelf Life:Three years
Payment:Multiple terms acceptable like T/T, LC, DA
Company Advantage:Kintai mainly focuses on the production of high content plant extracts and pharmaceutical intermediates all the year round
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Product Introduction

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of sinomenine hydrochloride in China. Please feel free to wholesale high quality sinomenine hydrochloride for sale here from our factory. For price consultation, contact us.

 

What is Sinomenine ?

 

Sinomenine hydrochloride (Sinomenine) comes from the dry root extract of Ivy (Sinomenium AcutumRehderettWilson). Ivy contains Igoginomenine, SinoAcutine, Acutumidine, Sinaetine, and Diginomenine. The main component is biological Alkali, soluble in ethanol, acetone, chloroform, and dilute alkali, slightly soluble in water, ethanol, and benzene (needle crystal).

 

sinomenine hydrochloride

 

Specification

 

Product name

Sinomenine

Extract source

Roots and Stems of Sinomenine

Extraction Solvent

Ethyl alcohol

Appearance

White powder

Solubility

Soluble in ethanol, acetone, chloroform, and dilute alkali, slightly soluble in water, ether, and benzene

Identification

TLC , HPLC

Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay of 98% Sinomenine (HPLC test, percent, Standard in House)

Min. 95.0%

Residual Solvents

 

- N-hexane

NMT 290 PPM

- Methanol

NMT 3000 PPM

- Acetone

NMT 5000 PPM

- Ethyl Acetate

NMT 5000 PPM

- Ethanol

NMT 5000 PPM

Pesticide Residues

 

- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT)

NMT 0.05 PPM

- Aldrin, Endrin, Dieldrin

NMT 0.01 PPM

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In a Tight, Light-resistant, and Dry Place. Avoid Direct Sunshine. Country of Origin: China

Shelf life

3 years

 

 Chemical & Physical Properties

 

CAS Number

6080-33-7

Molecular Weight

365.851

Density

N/A

Boiling Point

513.6ºC at 760 mmHg

Molecular Formula

C19H24ClNO4

Melting Point

231.0 to 235.0 °C

Common Name

Sinomenine

Flash Point

264.4ºC

Sinomenine

 

 

Benefits 

 

1. Analgesic effect: Sinomenine hydrochloride is an over-the-counter pain reliever commonly used to relieve various pain conditions. It reduces pain perception and provides relief by inhibiting the transmission of pain signals. It can be used for different types of pain such as headaches, joint pains, neuralgia, etc.

 

2. Anti-inflammatory effect: Sinomenine has an anti-inflammatory effect and can reduce inflammation symptoms. When human tissue is irritated or damaged, it triggers an inflammatory response, causing symptoms such as redness, pain, and heat. Sinomenine reduces the inflammatory response by inhibiting the production and release of inflammatory mediators, thereby alleviating the symptoms of inflammatory diseases, such as arthritis and rheumatoid.

 

Anti-inflammatory effect of Sinomenine Hydrochloride

 

3. Relaxes muscles: Sinomenine relaxes muscles, reducing muscle spasms and tension. It inhibits muscle contraction by affecting the release of neurotransmitters, thereby relieving muscle spasms and soreness. This is very helpful for the relief of symptoms such as sports injuries, muscle strains, and neck and shoulder syndrome.

 

4. Anti-allergic effect: Sinomenine can inhibit allergic reactions and play an anti-allergic effect. It can reduce the release of allergic mediators, such as histamine, thereby slowing down allergic symptoms, such as nasal congestion, runny nose, itchy skin, etc. Therefore, sinomenine is often used to treat allergic diseases such as allergic rhinitis and skin allergies.

 

5. Antidepressant effect: Sinomenine has an antidepressant effect. It can increase the concentration of neurotransmitters in the brain, such as dopamine, thereby improving mood and mood, and has a positive impact on some mild depression symptoms.

 

Antidepressant effect of Sinomenine Hydrochloride

 

 

Application

 

  • Pharmaceutical field: Sinomenine powder is an important pharmaceutical ingredient, often used in the preparation of analgesic, anti-inflammatory, sedative, anti-inflammatory, and anti-allergic drugs. It can be used to relieve pain symptoms such as headaches, joint pains, neuralgia, and muscle strains. In addition, sinomenine powder can also be used to treat inflammatory and allergic diseases such as arthritis, rheumatoid, allergic rhinitis, and skin allergies.

 

Sinomenine Hydrochloride apply in Pharmaceutical field

 

  • Cosmetics and personal care products: Sinomenine powder can be used in the formulation of skincare and personal care products to reduce skin inflammation and allergic reactions. It can be used to reduce facial redness, itching, peeling, and other sensitive skin problems, providing soothing and protective effects.

 

  • Animal medicine field: Sinomenine powder can be used to prepare medicines for pets and agricultural animals to provide analgesic, anti-inflammatory, and anti-allergic effects. It can be applied to the treatment of animal arthritis, muscle strain, allergic skin diseases, and other diseases.

 

Sinomenine Hydrochloride apply in Animal medicine field

 

  • Laboratory research: Sinomenine powder can also be used as a reagent in laboratory research, for cell culture, biological pathway research, etc. It can be used to observe the effects of drugs on processes such as inflammatory response and pain conduction in cells, providing important support for medical research and drug development.

 

Dosage and Reference formula

 

Dosage:

The dosage of sinomenine powder should be determined according to the specific situation of the patient and the doctor's advice.
In general, the dose is divided into daily doses and single doses. According to the characteristics of specific diseases and patients, the daily dose is usually between 5-15 mg, and the single dose is between 2-5 mg.
Dosage adjustment should be based on the patient's condition and tolerance. For special populations, such as children, the elderly and patients with impaired liver and kidney function, the dose may need to be adjusted accordingly.

 

Reference formula:

Sinomenine powder is usually used as the main ingredient in pharmaceutical preparations, so it is often used in combination with other drugs.
A common reference formula is to mix sinomenine powder with lactose or starch to make capsules or tablets.

 

In addition, according to specific conditions and needs, sinomenine powder can also be compounded with other drugs to enhance efficacy or reduce adverse reactions.
It should be noted that the dosage and reference formula given above are for reference only, and the specific dosage and formula should be determined according to the doctor's guidance and the actual situation of the patient.

 

Our manufacturing base

 

Kintai manufacturing base

 

Our R&D center

 

Kintai R&D center

 

 

Shipping and Packaging

 

Packing and shipping

 

★If you want to get high-quality Sinomenine Hydrochloride, please feel free to contact us at cheney@kintaibio.com or feedback on the next page.

 

 

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