Milk Thistle Extract Powder

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of Milk Thistle Extract Powder in China. Please feel free to wholesale high quality Milk Thistle Extract Powder for sale here from our factory. For price consultation, contact us.

KINTAIBIO^®'s milk thistle extract is derived from carefully selected mature fruits of the Asteraceae plant, Silybum marianum (L.) Gaertn. Research has shown that milk thistle seeds are rich in protein, unsaturated fatty acids, and various minerals, and are a valuable source of numerous natural active ingredients. Using advanced extraction and purification technologies, we precisely extract and standardize the core active ingredient in milk thistle-a complex of flavonolignans, primarily silybin. 

Silybum marianum (L.)

Milk Thistle

Milk Thistle Seeds

Our core product line meets international standards:

Silybin boasts a purity of up to 98%, providing strong support for high-end products.

Silymarin is available in various strengths (30%-80%) and complies with EP/USP standards, ensuring consistent efficacy.

Our innovative water-soluble silymarin (40%) overcomes the solubility issues of traditional extracts, expanding its application areas.

Silybin 98%

Silymarin 80%

Water-Soluble Silymarin 40%

Through rigorous quality control systems (HPLC/UV), we ensure consistent ingredient content in every batch. This not only enhances the value of the raw material but also provides reliable assurance for highly effective and unique end products.

Send Inquiry Details And Get A Free Sample And Get The Latest Price >>

Milk thistle's pharmacological activities, such as hepatoprotection and anti-inflammatory, stem from the synergistic effects of its diverse components. KINTAIBIO^® is dedicated to transforming this natural complexity into standardized, highly effective raw materials. Our extracts retain the key functional components identified in milk thistle extract powder , including flavonolignans (such as silybin and silymarin), flavonoids, phenolic acids, and other naturally occurring synergistic compounds.

To meet diverse needs, we offer a variety of strengths: For products seeking a single efficacy, choose 98% pure silybin; for products requiring a full spectrum of synergistic benefits, choose 80% standardized silymarin; and for aqueous solutions like beverages and oral solutions, 40% water-soluble silymarin provides an ideal, highly bioavailable solution. All products undergo rigorous testing to ensure clear composition and defined active ingredients. For more detailed specifications, please refer to the table below:

Choosing KINTAIBIO^® means you receive a scientifically validated active ingredient system, providing reliable, natural support for your pharmaceuticals and health supplements. If you are interested in our above specifications, please feel free to contact sales@kintaibio.com to obtain samples and for more detailed consultation.

If you need other specifications of COA, please contact sales@kintaibio.com.

KINTAIBIO^® has always believed that excellent products are inseparable from precise processes. Through numerous experiments and optimization, we have determined the optimal extraction method for silymarin: repeated extractions using an ethanol solution of a specific concentration at precisely controlled temperature and time. The extract is then purified using a carefully selected resin, employing gradient elution to remove impurities and enrich the target component. This systematic extraction and purification process results in a light yellow product with a uniform texture and a stable silymarin content , ensuring reliable efficacy.

We also prioritize environmental protection and safety, strictly controlling every production step. We utilize a fully enclosed automated production system, ensuring that extraction, filtration, and concentration processes are all carried out under sealed conditions. Advanced solvent recovery technology effectively recycles solvents from medicinal residues, keeping residual levels below 500 ppm. This ensures production safety while enabling solvent recycling and reducing resource waste. Furthermore, the dried medicinal residues can be reused as feed or fertilizer, supporting a green, circular economy. This fully demonstrates that while we provide high-quality natural raw materials, we also fulfill our corporate environmental responsibility.

Our company produces high-purity milk thistle extract, whose core active ingredient is silymarin. Numerous scientific studies have confirmed that silymarin possesses multiple biological activities, including excellent liver protection, antioxidant, anti-inflammatory, glucose and lipid metabolism regulation, and antibacterial properties. These activities provide a solid theoretical and practical basis for its widespread application in the pharmaceutical, health product, feed, and food industries.

milk thistle extract supplement

Silymarin is an internationally recognized natural liver protectant with a well-defined mechanism of action:

• Strong liver protection: By preventing lipid peroxidation, scavenging free radicals, and increasing liver glutathione (GSH) levels, it effectively repairs liver cell damage and combats chemical liver damage.
• Metabolic regulation: By increasing insulin and glucagon expression, it helps regulate blood sugar; and by improving dyslipidemia, it exerts cardiovascular protection.
• Renal protection: It can inhibit the elevation of nephrotoxicity markers such as serum creatinine, uric acid, and blood urea nitrogen.

It can be used as liver-protecting milk thistle extract capsules,milk thistle extract pills and milk thistle extract tablets. It can also be used as a functional ingredient in the development of health foods that assist in regulating blood sugar and lipids, provide antioxidant benefits, and promote hangover relief and liver protection.

Feed Additive Industry

• Sow Farming

It improves sow performance: significantly increasing average daily feed intake from 1 to 21 days postpartum and effectively boosting milk production. It also promotes piglet growth, significantly increasing suckling piglet weights at 14 and 21 days of age, as well as average daily weight gain from 1 to 21 days of age.

• Aquaculture

It significantly increases the weight gain rate of hybrid grouper juveniles and reduces feed conversion ratios. It can also improve animal liver cell morphology, reduce cellular vacuoles, and significantly lower serum total cholesterol, triglyceride, and transaminase levels.

In terms of antioxidant activity, silymarin can significantly increase the activity of antioxidant enzymes such as glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in the liver.

This product significantly improves the survival rate of Mandarin Fish in culture. It can be used to optimize feed utilization and reduce feed conversion ratio.

• Poultry Farming

Improves Egg Production Performance: Significantly increases egg production rate and average egg weight, and reduces feed-to-egg ratio.

Improves Egg Quality: Increases yolk index, reduces malondialdehyde (MDA) content in egg yolk, and enhances antioxidant levels.

Our milk thistle extract powder products, with their clear active ingredients, robust scientific research data, and extensive application scenarios, provide high-value natural ingredient solutions for customers across various downstream industries. Whether it's pharmaceuticals and health supplements to enhance human health,or feed additives to improve animal production efficiency, we provide professional technical support and a stable product supply.

milk thistle extract for liver

Milk thistle extract is a widely used traditional botanical ingredient for liver protection; its primary active component, silymarin, has been extensively studied for its role in maintaining liver health. Recent research has increasingly focused on the potential of milk thistle to modulate oxidative stress and inflammation associated with non-alcoholic fatty liver disease (NAFLD). Animal studies have demonstrated that supplementation with pure milk thistle extract can alleviate abnormal hepatic lipid accumulation and help restore the body's antioxidant status.

 

Research indicates that the flavonolignans found in milk thistle can enhance the activity of antioxidant enzyme systems-thereby boosting endogenous antioxidant defenses-while simultaneously reducing the levels of cytokines associated with liver inflammation, thus helping to maintain normal hepatocyte function. Based on existing clinical findings, milk thistle standardized extract exhibits a favorable safety and tolerability profile; it is currently regarded primarily as a functional nutritional ingredient that supports liver health and modulates oxidative stress and inflammatory responses.

milk thistle extract diabetes

In recent years, extract of milk thistle has garnered attention for its potential roles in modulating oxidative stress, controlling inflammation, and supporting metabolic health. Research indicates that in models of type 2 diabetes, chronic hyperglycemia can induce oxidative damage, exacerbate inflammatory responses, and disrupt insulin signaling pathways; silybin, a key component, may help maintain metabolic homeostasis through multiple mechanisms.

 

Animal studies have shown that silybin intervention can modulate glucose metabolism-related signaling pathways-specifically PI3K/AKT/GLUT2 and AMPK/GLUT2-thereby ameliorating abnormalities caused by hyperglycemia and exogenous oxidative stress. Furthermore, silybin regulates inflammation-related factors (such as IL-1β and IL-10), markers of lipid peroxidation (e.g., MDA), and antioxidant defense systems (SOD, CAT, GPX, GSH, and HO-1), thereby helping to mitigate the impact of oxidative stress and inflammation on pancreatic tissue.

milk thistle extract benefits for skin

Exposure to ultraviolet radiation, environmental pollution, and oxidative stress can lead to the excessive production of reactive oxygen species (ROS) in the skin. This process induces inflammatory responses and promotes the aberrant expression of matrix metalloproteinases (MMPs), thereby compromising skin barrier function and collagen stability.

 

Research has shown that silymarin inhibits the activity of gelatinases MMP-9 and MMP-2-enzymes associated with extracellular matrix degradation-thereby reducing gelatinolysis while simultaneously attenuating oxidative stress-induced inflammation. In both *in vitro* cellular assays and animal models, silymarin has demonstrated significant potential for skin protection, effectively mitigating inflammation-associated tissue damage and alleviating ROS-mediated cutaneous inflammation.

Reference:https://www.sciencedirect.com/science/article/pii/S2405844024074760

https://www.sciencedirect.com/science/article/abs/pii/S0955286324002675

https://www.sciencedirect.com/org/science/article/pii/S1478641924002870

Safety of Milk Thistle Extract

high quality milk thistle extract is widely used in dietary supplements and products supporting liver health and functional nutrition, thanks to the excellent safety and tolerability profile of its primary active ingredient, silymarin. When taken within recommended dosage ranges, milk thistle is generally considered safe, with most users experiencing no significant adverse reactions.

Dosage of Milk Thistle Extract

Dosages of silymarin supplements in clinical studies vary depending on product standardization and the intended use; a daily range of approximately 200–400 mg of silymarin is commonly employed. Specific intake should be adjusted based on product specifications, active ingredient content, and professional advice.

Side Effects of Milk Thistle Extract

Existing research indicates a low incidence of adverse reactions. A small number of users may experience mild gastrointestinal discomfort-such as bloating, nausea, flatulence, or diarrhea-while some individuals may report headaches, itching, or mild allergic reactions. As milk thistle belongs to the Asteraceae (daisy/sunflower) family, individuals with allergies to related plants should exercise caution to avoid potential allergic risks. Additionally, milk thistle concentrated extract may interact with certain medications; therefore, individuals undergoing medical treatment, as well as pregnant or breastfeeding women, should consult a healthcare professional before use.

• NCCIH: Oral use of milk thistle is generally well-tolerated; common side effects include bloating, nausea, and flatulence, with a warning for caution among those allergic to Asteraceae plants.
• NCI Data: Multiple randomized controlled studies show few adverse reactions to silymarin, though high doses may increase the risk of mild allergic reactions.
• US FDA Dietary Supplement Regulations: Dietary supplements generally do not require FDA approval for efficacy prior to marketing, but manufacturers are responsible for product safety and labeling compliance.

KINTAIBIO^® is a professional milk thistle extract manufacturer and reliable milk thistle extract supplier, dedicated to providing high-quality standardized milk thistle extract powder for customers worldwide. With advanced extraction technology, strict quality control systems, and stable production capacity, we supply premium plant-based ingredients for pharmaceuticals, dietary supplements, functional foods, and animal nutrition applications.

For customers looking to buy milk thistle extract powder, we offer a wide range of specifications to meet different formulation requirements. Our products include high-purity Silybin up to 98% for advanced pharmaceutical applications, standardized silymarin extracts ranging from 30%-80% for health supplements, as well as 40% water-soluble silymarin designed for innovative formulations. As a trusted milk thistle extract powder factory, we focus on consistent quality, excellent solubility solutions, and customized specifications to support global brands and manufacturers.

Whether you are searching for milk thistle extract powder for sale, wholesale milk thistle extract powder, or a long-term manufacturing partner, KINTAIBIO^® provides competitive milk thistle extract price options based on product specifications, order quantity, and customization requirements. Through standardized production processes and rigorous testing procedures, we ensure batch-to-batch consistency, helping customers optimize formulations, improve production efficiency, and accelerate product development.

If you are looking for a reliable milk thistle extract near me or an experienced global supplier of customized milk thistle extract powder, please contact us at Sales@Kintaibio.Com for product details, technical support, and customized solutions.

Hot Tags: Milk Thistle Extract Powder, China Milk Thistle Extract Powder manufacturers, suppliers, factory, Cordyceps Mycelium Extract, Mango Leaf Extract, Helicid Powder, Astilbin Powder , Green Coffee Bean Extract Powder Chlorogenic Acid, Black Bean Extract Anthocyanins