Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of Grape Seed Extract Powder in China. Please feel free to wholesale high quality Grape Seed Extract Powder for sale here from our factory. For price consultation, contact us.
Grape Seed Extract Powder factory/manufacturer
As a professional Grape Seed Extract Powder manufacturer, KINTAIBIO® relies on advanced extraction technology and a strict quality management system. We hold GMP, ISO9001:2015, ISO22000:2018, HACCP, and HALAL certifications to ensure quality control throughout the entire supply chain. We offer a full range of high-quality grape-derived raw materials, covering various specifications and active ingredient concentrations:

- Grape Seed Extract Powder, derived from grape seeds, is available in specifications including proanthocyanidins (90%-99%), water-soluble proanthocyanidins (95%), and polyphenols (45%-95%), as well as oligomeric proanthocyanidins (70%) as determined by USP standard HPLC;
- Red Grape Extract Powder, extracted from whole grapes, is available in specifications with 70% polyphenols (UV);
- Grape Skin Extract Powder, derived from grape skins, offers 20%-90% polyphenols (UV), 1%-5% resveratrol (HPLC), 20-40% proanthocyanidins (HPLC), and 2%-6% anthocyanidins (UV);
- Grape Leaf Extract Powder, extracted from grape leaves, is available in specifications with 5% resveratrol (HPLC) and 30% proanthocyanidins (UV);
- Grape Stem (Vine) Extract, selected from grapevines or stems. Our products include Grape Powder containing 5% trans-resveratrol and 2%-10% ε-glucan (both determined by HPLC);
- Grape Fruit Powder made from fresh grape juice through juicing, filtration, and spray drying to a fineness of 80 mesh;
- Grape Seed Powder made from grape seeds finely ground to 80 mesh.

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Our products are made from 100% food-grade, all-natural ingredients, free of any additives, and can be widely used in dietary supplements, functional foods, high-end skincare, and animal nutrition. We welcome you to select the appropriate specifications based on your project needs, and we support customized production and services. With rigorous processes, stable quality, and transparent ingredient data, we provide reliable Grape Powder to meet the R&D and production needs of clients in various fields. Please contact us at sales@kintaibio.com for product information.



TDS Of Grape Seed Extract powder
| ITEMS | SPECIFICATION | TEST METHOD |
| Appearance | Reddish brown powder | Visual |
| Odor&Taste | Not rancid and other odors,Not visible impurities | Organoleptic |
| Identification | Positive | TLC |
| Assay Of Procyanidine | ≥95% | UV |
| OPC(Oligomeric Proanthocyanidins) Content |
≥80% | HPLC |
| Loss on drying | ≤5.0% | 2g/105℃/3hrs |
| Ash | ≤5.0% | 2g/105℃/3hrs |
| Mesh Size/Sieve | NLT 95% Through 80 mesh | CP2020 |
| Heavy Metals | ≤10ppm | ICP-MS |
| Lead(Pb) | ≤1ppm | ICP-MS |
| Arsenic(As) | ≤1ppm | ICP-MS |
| Cadmium(Cd) | ≤1ppm | ICP-MS |
| Mercury (Hg) | ≤0.1ppm | ICP-MS |
| Residual Solvent | ≤5000ppm | GC-ECD |
| Ethanol | ≤5000ppm | GC-ECD |
| Total Plate Count | ≤30000cfu/g | AOAC 990.12 |
| Total Yeast &Mold | ≤300cfu/g | AOAC 991.14 |
| E.Coli. | Negative/10g | AOAC 997.02 |
| Salmonella | Negative/10g | AOAC 998.09 |
| GMO Status | Non-GMO | PCR / Elisa |
| Storage | product may be stored for 24 months from the date of manufacture in the unopened original container. Keep container tightly closed under cool and light proof conditions. Once opened, use contents quickly. Temperature limits , 0-30℃,The relative Humidity: 45-70% |
|
| Package | The Packed in paper-drums and two plastic-bags inside. | |
| Shelf life | 24month | |
How to make Grape Seed Extract Powder?

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Pretreatment and Separation
The received fresh grape pomace is processed using specialized screening and separation equipment to quickly separate it into three main components: grape skins, grape seeds, and debris. The key is "immediate separation" to prevent microbial fermentation or oxidation that could lead to the loss of polyphenols in the seeds. The separated grape seeds need to be washed, dried at low temperature to control moisture, and undergo preliminary screening to remove residual impurities.
Extraction and Solid-Liquid Separation
The extraction solvent is prepared strictly according to an ethanol:water ratio of 70:30 (v/v). This ensures efficient dissolution of polyphenols from the grape seeds while inhibiting excessive leaching of unnecessary monomers. The pretreated grape seeds and solvent are added to a pressure-resistant extraction tank at a feed-to-liquid ratio of 1:10 (w/v). The entire extraction process is conducted under "low oxygen, low humidity, and high pressure" conditions. "Low oxygen" is achieved by purging the tank with inert gases such as nitrogen to replace the air; "low humidity" is achieved by dehumidifying the sealed environment; and pressurization is used to improve solvent penetration and the efficiency of dissolving active ingredients. After extraction, a polyphenol-rich liquid extract is obtained by filtration or centrifugation. The residue can be further processed for grape seed oil production.
Concentration and Refining
The extract is pumped into a vacuum concentrator. Under low temperature and reduced pressure, most of the water and some ethanol are evaporated to obtain a high-concentration grape seed extract paste. This significantly reduces subsequent drying energy consumption and minimizes damage to heat-sensitive components.
Drying and Finished
The concentrated paste is dried. Spray drying (controllable inlet temperature, e.g., 150-180℃, outlet temperature 70-90℃) or vacuum belt drying processes can be used to obtain a free-flowing grape seed extract powder. The powder may undergo further refining steps (such as secondary purification and standardized mixing) to ensure that the polyphenol content in the final product consistently meets predetermined specifications (e.g., 95% OPC). Finally, under controlled temperature and humidity conditions, the finished powder is packaged in nitrogen-filled aluminum foil bags or vacuum-packed to maintain stability.
benefits of Grape Seed Extract powder
Grape Seed Extract powder for skin
KINTAIBIO®'s Grape Seed Extract Powder boasts exceptional skincare benefits. Its core ingredient lies in grape seed extract, rich in high concentrations of polyphenols, particularly potent proanthocyanidins. These molecules are natural antioxidants that effectively neutralize free radicals that contribute to skin aging and combat oxidative damage. To further enhance its bioavailability and efficacy, advanced carrier technologies (such as liposomes and hyaluronic acid molecule) effectively encapsulate and deliver it, significantly boosting skin cell vitality and self-protection capabilities, and tangibly improving skin condition.

Source:https://www.mdpi.com
A 12-week human trial demonstrated that continued use of formulations containing this extract effectively improves skin hydration, reduces wrinkle depth, and helps soothe and even out skin tone. Therefore, our Grape Seed Extract Powder is not only a natural antioxidant but also a scientifically proven, highly effective active ingredient that supports skin health and combats signs of aging.
Grape Seed Extract powder for dogs
Grape seed extract powder, especially its high-purity proanthocyanidins, plays an effective role in supporting canine gut health. Studies have shown that in dogs with mild inflammatory bowel disease (IBD), grape seed proanthocyanidins can effectively improve intestinal inflammatory markers and reduce intestinal permeability, thereby alleviating persistent digestive discomfort. Its core mechanism of action lies in precisely regulating the gut microbiota: it significantly increases the abundance of beneficial bacteria with potential anti-inflammatory properties, such as Ruminococcus and Faecalibacterium, while simultaneously optimizing bile acid metabolism and promoting the production of beneficial metabolites such as lithocholic acid.

Source:https://faseb.onlinelibrary.wiley.com
Femtomicrobial transplantation experiments further confirm that this positive improvement in gut microbiota composition is key to the therapeutic effects of grape seed proanthocyanidins. Our grape seed extract powder is not only a potent antioxidant but also a natural dietary component that can maintain canine intestinal barrier function and balance immune responses through multiple targets along the "microbiota-metabolism" axis.
Grape Seed Extract powder benefits for men
Benign prostatic hyperplasia (BPH) is a common chronic problem affecting the urinary system of middle-aged and older men, and research has shown that the active ingredients in Grape Seed Extract Powder can effectively intervene in this process. Animal model experiments have shown that the processed version rich in oligomeric proanthocyanidins (ATGSE) demonstrates superior performance compared to traditional extracts in reducing prostate and seminal vesicle weight, significantly reducing prostate-specific antigen (PSA) levels, and inhibiting the expression of key pro-inflammatory factors.

Source:https://www.mdpi.com
These findings confirm that grape seed extract helps alleviate BPH and related discomfort through anti-inflammatory effects and the regulation of related biomarkers. Therefore, our product not only provides high-concentration polyphenol antioxidant support but also serves as a potential nutritional supplement or functional food ingredient to help maintain male prostate health and overall urinary system function.
Grape Seed Extract powder and testosterone
Animal model studies have revealed that under oxidative stress induced by factors such as drugs, grape seed extract can effectively combat oxidative damage in testicular tissue, significantly reducing the negative impact of harmful substances on testicular weight and structure. Its mechanism of action includes supporting key enzymatic and non-enzymatic antioxidant defense systems (such as increasing glutathione levels), thereby helping to maintain the homeostasis of testicular cells.

Source:https://onlinelibrary.wiley.com
Further research results indicate that this protective effect is directly linked to important physiological indicators: supplementation with grape seed extract helps improve plasma testosterone levels under damaged conditions and has a positive effect on maintaining the healthy morphological structure of testicular tissue. Therefore, our Grape Seed Extract Powder, with its superior antioxidant and cellular protective capabilities, demonstrates positive scientific potential in maintaining male testicular health and function.
Reference:https://www.mdpi.com/2079-9284/12/2/38
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202300819RR
https://www.mdpi.com/2072-6643/17/1/73
https://onlinelibrary.wiley.com/doi/abs/10.1111/and.13002
Grape Seed Extract powder uses
Based on a strong scientific foundation and extensive application validation, our Grape Seed Extract Powder, a high-quality source of high-purity proanthocyanidins, has expanded its applications from traditional dietary supplements to innovative areas such as daily cosmetics and sustainable agriculture.
grape seed extract powder supplement

As a core ingredient in dietary supplements, our highly active grape seed extract powder is an ideal raw material for producing best proanthocyanidin supplements. Its main standardized component is proanthocyanidins, which possess powerful antioxidant activity and have been widely studied by the scientific community. Based on this raw material, it can be processed into various convenient dosage forms, such as Grape Seed Extract powder capsules, Grape Seed Extract powder tablets, and proanthocyanidin tablets. These supplements are designed to provide consumers with high-concentration natural antioxidant support for daily health maintenance.
Grape Seed Extract Powder skincare products

Grape Seed Extract Powder, a key active ingredient in high-end cosmetics and skincare products, is widely used in cosmeceuticals and skincare due to its exceptional free radical scavenging capabilities and rich content of various bioactive substances. It is a crucial active ingredient in many anti-aging serums, creams, and lotions, helping to combat environmental damage and improve skin health by reducing oxidative stress and improving the skin's redox state, thus delaying the appearance of aging.
Grape Seed Extract powder side effects
While our Grape Seed Extract is safe for most people at recommended doses, it is crucial to understand its potential precautions as it is a highly active ingredient.
- Some users may experience mild gastrointestinal reactions such as nausea or stomach upset, or occasionally dizziness or headaches. Of particular importance is that, because the extract may affect blood clotting and has a certain blood pressure-lowering effect, individuals taking anticoagulants (such as warfarin or aspirin) or blood pressure medications must consult a doctor before use to avoid potential interactions and risks.
- Furthermore, those allergic to grapes or related products should not use this product. Additionally, due to a lack of sufficient safety research data, we generally do not recommend use by pregnant women, breastfeeding women, or children.
We strongly recommend that you seek professional medical advice before starting any new dietary supplement (including this product), especially if you have underlying medical conditions or are taking other medications.
where can i buy grape seed extract powder?
We offer comprehensive extract solutions covering the entire grape plant. Our Grape Seed Extract Powder provides proanthocyanidin levels ranging from 90% to 99%, as well as 70% oligomeric proanthocyanidins as determined by USP standard HPLC; our Grape Skin Extract Powder, derived from grape skins, offers up to 90% polyphenols and 1%-5% resveratrol; our Grape Leaf Extract Powder and Grape Stem Extract Powder, extracted from grape leaves and vines, are rich in highly active trans-resveratrol and the unique ingredient ε-glucan; and we also offer directly ground Grape Fruit Powder and Grape Seed Powder. For markets seeking ingredient differentiation, we can provide the most suitable active ingredient specifications for your application.

International Quality Foundation and Authoritative Compliance Guarantee

Our production process strictly adheres to international cGMP standards and has obtained authoritative certifications such as NSF, Kosher, and Halal, ensuring that our production system is aligned with the highest international standards. In terms of quality control, we not only adhere to international standards, rigorously measuring the content of active ingredients (such as proanthocyanidins and resveratrol) in each batch of products using HPLC/UV, but also conduct comprehensive screening for heavy metals, pesticide residues, and microorganisms to ensure product purity and stable efficacy.
Professional Customized Services and Smooth Cooperation Processes
KINTAIBIO® offers in-depth and flexible OEM/ODM services, customizing functional premixes specifically for your brand based on your specific formulation needs. Our cooperation process is clear and efficient: from initial needs communication and technical solution matching, to providing sample testing and detailed product specifications and test reports, and finally signing the contract and arranging dedicated production, our professional team will provide full support. We focus on serving brand owners, manufacturers, and large trading companies, ensuring that from samples to large-volume orders, you receive consistent quality, stable supply of raw materials, and an efficient and reliable supply chain.
We sincerely invite global partners. Please inform us of your specific needs at sales@kintaibio.com, and our technical sales team will immediately provide you with professional product solutions and quotations.

FAQ
Q: Is grape seed extract powder truly beneficial to health?
A: Yes, a wealth of existing scientific research indicates that grape seed extract is a valuable health supplement. Its core benefits are primarily attributed to its high concentration of proanthocyanidins, a powerful natural antioxidant. Studies have shown it helps fight free radicals, supports cardiovascular health, maintains skin elasticity, and has demonstrated positive potential in specific health areas in numerous studies. However, as a dietary supplement, it should not replace a balanced diet or medication.
Q: Can children take grape seed extract powder?
A: Based on current scientific research, we do not recommend that children take grape seed extract on their own. Any decision to supplement children with such products must be made under the full evaluation and clear guidance of a pediatrician or other healthcare professional to ensure absolute safety.
Q: Will grape seed extract powder burden or damage the liver?
A: According to existing scientific research, moderate consumption of high-quality grape seed extract is generally considered safe for the liver. On the contrary, several studies have pointed to its potential liver-protective effects. The core mechanism is believed to be related to the powerful antioxidant and anti-inflammatory properties of its high concentration of proanthocyanidins, which help reduce oxidative stress and inflammatory damage to the liver.
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