Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of Proanthocyanidins Powder in China. Please feel free to wholesale high quality Proanthocyanidins Powder for sale here from our factory. For price consultation, contact us.
proanthocyanidins powder factory/manufacturer
KINTAIBIO® is a supplier specializing in multi-plant-derived proanthocyanidins powder. We offer highly active extracts from the entire grape plant, including grape seeds, skins, and leaves, as well as highly active proanthocyanidins derived from pine bark and sorghum. In terms of specifications, we provide standard specifications with proanthocyanidin content up to 95% UV, and also support a variety of ingredient gradients from basic to professional: for example,Grape Seed Extract Powder includes 90%-99% proanthocyanidins, 95% water-soluble proanthocyanidins, and 45%-95% polyphenols; Grape Skin Extract Powder offers 20%-40% HPLC proanthocyanidins and 20%-90% UV polyphenols; and grape leaf extract contains 30% UV proanthocyanidins and 5% HPLC resveratrol, among other options, precisely tailored to different R&D and production needs.
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Regarding quality control, we rely on a rigorous management system covering the entire chain from extraction and purification to finished product, employing multiple detection technologies such as UV and HPLC to ensure accurate labeling of active ingredients. Our factory holds multiple international certifications, including GMP, ISO9001, ISO22000, HACCP, and HALAL. Each batch comes with a traceable Certificate of Analysis (COA), providing our clients with stable and reliable raw material guarantees for applications in dietary supplements, daily chemical products, and animal nutrition.
We emphasize collaborative innovation with our clients and can provide customized support based on specific projects, including raw material sourcing, ingredient ratios, dosage form design, and compounding solutions. Leveraging our mature process platform, sustainable large-scale supply system, and professional technical services, we have established long-term partnerships with numerous domestic and international companies. For more product information or to discuss customization needs, please contact us at sales@kintaibio.com.
Proanthocyanidins powder Component detection methods
Detection Principle and Standards
The UV-Vis spectrophotometry method is used, based on a standard chemical colorimetric reaction. Absorbance is measured at a characteristic wavelength of 546 nm, ensuring high specificity.
Key Operations and Parameters
Sample Preparation: Accurately weigh approximately 10 mg of sample, dissolve in methanol, and dilute to volume.
Colorimetric Reaction: React precisely in a 100℃ water bath for 40 minutes, followed by rapid cooling to ensure complete and stable reaction.
Blank Control: Prepare a reagent blank simultaneously for correction to eliminate background interference.
Quality Assurance Basis
Analytical grade reagents and Grade III water conforming to GB/T6682 are used.
Key instruments include an analytical balance with a sensitivity of 0.01 mg and a UV-Vis spectrophotometer.
Result Calculation and Reporting
Proanthocyanidin values are calculated using the formula (W1 = A1 × 7200 / M1 × 275) to ensure accurate and traceable results for each batch, which are reflected in the COA (Contribution Analysis Report).
TDS Of Proanthocyanidins powder
| ITEMS | SPECIFICATION | TEST METHOD |
| Appearance | Reddish brown powder | Visual |
| Odor&Taste | Not rancid and other odors,Not visible impurities | Organoleptic |
| Identification | Positive | TLC |
| Assay Of Procyanidine | ≥95% | UV |
| OPC(Oligomeric Proanthocyanidins) Content |
≥80% | HPLC |
| Loss on drying | ≤5.0% | 2g/105℃/3hrs |
| Ash | ≤5.0% | 2g/105℃/3hrs |
| Mesh Size/Sieve | NLT 95% Through 80 mesh | CP2020 |
| Heavy Metals | ≤10ppm | ICP-MS |
| Lead(Pb) | ≤1ppm | ICP-MS |
| Arsenic(As) | ≤1ppm | ICP-MS |
| Cadmium(Cd) | ≤1ppm | ICP-MS |
| Mercury (Hg) | ≤0.1ppm | ICP-MS |
| Residual Solvent | ≤5000ppm | GC-ECD |
| Ethanol | ≤5000ppm | GC-ECD |
| Total Plate Count | ≤30000cfu/g | AOAC 990.12 |
| Total Yeast &Mold | ≤300cfu/g | AOAC 991.14 |
| E.Coli. | Negative/10g | AOAC 997.02 |
| Salmonella | Negative/10g | AOAC 998.09 |
| GMO Status | Non-GMO | PCR / Elisa |
| Storage | product may be stored for 24 months from the date of manufacture in the unopened original container. Keep container tightly closed under cool and light proof conditions. Once opened, use contents quickly. Temperature limits , 0-30℃,The relative Humidity: 45-70% |
|
| Package | The Packed in paper-drums and two plastic-bags inside. | |
| Shelf life | 24month | |
How to make Proanthocyanidins powder?
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We immediately separate material from fresh, unfermented/lightly fermented grape pomace, preserving the original activity and high content of polyphenols to the greatest extent possible from the source, avoiding degradation caused by prolonged fermentation. In terms of production process, we have optimized the selective extraction of target polyphenols such as proanthocyanidins, achieving an ideal ratio of high total polyphenol content to low monomer content, resulting in better product bioavailability and synergistic effects.
Our production process inhibits oxidation and hydrolysis reactions throughout, protecting the chemical structure of active ingredients such as polyphenols and improving product purity and stability. The resulting Proanthocyanidins Powder is characterized by high content of active ingredients, strong antioxidant activity, pure color, and good batch-to-batch stability, giving it a core competitive advantage in the health food and cosmetic raw material market.
Proanthocyanidins powder health benefits
Proanthocyanidins powder hair growth
High concentrations of Proanthocyanidins extract provide dual scientific support for hair health and growth. Studies have confirmed that Proanthocyanidins significantly promote hair follicle cell activity-experiments have shown an approximately 230% increase in hair follicle cell proliferation in mice and effectively drive the transition of hair from the resting to the anagen phase, demonstrating its potential as a natural hair growth promoter.
Source:https://pmc.ncbi.nlm.nih.gov
Related research indicates that Proanthocyanidins Powder derived components effectively improve hair shine, enhance elasticity, and help repair damage caused by sun exposure, dyeing, perming, or styling, making them suitable for all hair types. Therefore, KINTAIBIO®'s Proanthocyanidins powder not only supports the hair growth cycle from the root but also helps maintain strong, shiny, and overall healthy hair through its antioxidant and repair properties in topical care.
grape seed extract Proanthocyanidins benefits for women
Our Proanthocyanidins powder is rich in highly bioactive polyphenols. An 8-week randomized, double-blind, controlled study confirmed that daily supplementation with Proanthocyanidins effectively improves core menopausal symptoms in middle-aged women: significantly alleviating physical symptoms such as hot flashes and insomnia, reducing anxiety, and helping to lower blood pressure. It also supports positive changes in body composition, such as increased muscle mass.
Source:https://www.frontiersin.org
Further research suggests that proanthocyanidins, such as B2, may play a potentially positive role in broader female reproductive physiology, including ovarian health, steroid production, and oocyte support, by regulating reproductive hormone balance and influencing related signaling pathways. Therefore, our Proanthocyanidins Powder is an evidence-based, natural ingredient designed to support women in coping with the challenges of specific physiological stages and promote overall health, both physically and mentally.
Reference:https://pubmed.ncbi.nlm.nih.gov/9833041/
https://pmc.ncbi.nlm.nih.gov/articles/PMC9996578/
https://pubmed.ncbi.nlm.nih.gov/24518152/
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1245512/full
Proanthocyanidins powder uses
High-purity proanthocyanidin powder derived from grape has been widely used in various health products due to its excellent antioxidant activity and bioavailability. Studies have shown that standardized extraction of proanthocyanidins (usually in oligomer form as the main active form) can effectively support cardiovascular health, maintain capillary integrity, and help alleviate oxidative stress. Our proanthocyanidin powder can be used directly in oligomeric proanthocyanidins supplement ,such as capsule, tablet, or powder formulations.
where can i buy Proanthocyanidins powder?
As a Chinese manufacturer of proanthocyanidins powder, KINTAIBIO® provides you with a direct and reliable source of highly active plant extracts. If you are evaluating where to purchase proanthocyanidins or looking for a trustworthy proanthocyanidin powder supplier, choosing us will give you significant advantages in quality control, cost-effectiveness, and technical support.
Your Partner for Customized Solutions
If your project requires specific specifications or blends of different proanthocyanidin sources (pine bark, sorghum), or custom formulations for dietary supplements, functional foods, or cosmetics, our technical team can provide professional R&D support to meet the regulatory and functional requirements of your application scenarios.
Contact Us for Quotes and Technical Information
If you wish to purchase proanthocyanidins powder and enjoy guaranteed quality and professional service, please contact our sales team directly at sales@kintaibio.com. We will provide you with comprehensive product information, samples for evaluation, and a competitive quote tailored to your needs.
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