Part1:What is Chrysanthemum indicum extract linarin?
Wild chrysanthemum extract is a yellow-brown powdery mixture rich in flavonoids extracted from the dry flower heads of Chrysanthemummorifolium Ramat. It is widely distributed in the northern hemisphere and is distributed in all provinces and autonomous regions of my country. It grows on hillsides, ditch sides, roadsides, grasslands, etc. Wild chrysanthemum is a commonly used Chinese herbal medicine, which has the functions of dispelling wind, clearing away heat, improving eyesight and detoxifying.
In recent years, pharmacological studies have found that the wild chrysanthemum extract has pharmacological effects such as antibacterial, antiviral, anti-inflammatory and immune, cardiovascular system protection, anti-tumor, liver protection and neuroprotection, and has good clinical application value and potential.
Part2:The functions of Chrysanthemum indicum extract linarin
1.Antibacterial effect
Wild chrysanthemum has a wide antibacterial spectrum. Its decoction and ethanol extract are tested in vitro against Staphylococcus aureus, Mycobacterium tuberculosis, Bacillus diphtheria, Escherichia coli, hemolytic streptococcus, various types of Shigella, Pseudomonas aeruginosa, Proteus , Vibrio cholerae and BCG have inhibitory effects. Wild chrysanthemum granule (Xiangrui, Huoxiang, wild chrysanthemum, Artemisia annua) has obvious inhibitory effect on other bacteria and intestinal bacteria except Staphylococcus aureus, which are common bacteria that cause respiratory diseases.
2. Antiviral effect
Wild chrysanthemum decoction and extract have inhibitory effect on influenza virus in vitro. 1:80 can delay the lesions of cells (primary monolayer epithelial cells of human embryonic kidney) infected by the orphan virus ECHO11. It also has a certain inhibitory effect on herpes virus. Yejuhua granule also has inhibitory effect on the proliferation of Poliv and VSV viruses.
3. Effect on immune function
Wild chrysanthemum decoction can enhance the phagocytic function of phagocytes. In vitro, it can promote the phagocytosis of Staphylococcus aureus by human leukocytes, and intravenous injection can significantly improve the phagocytosis of peritoneal macrophages in mice.
4. Effect on platelet aggregation
Intravenous injection of wild chrysanthemum decoction into rats has obvious inhibitory effect on ADP-induced platelet aggregation and rabbit muscle collagen-induced platelet aggregation.
5. Antihypertensive effect
Its antihypertensive principle is related to its anti-adrenaline, expansion of peripheral blood vessels and inhibition of vasomotor center.
6. The effect on cardiovascular
The wild chrysanthemum preparation has an effect on the heart while lowering blood pressure, and has a significant protective effect on experimental myocardial ischemia or myocardial infarction.
7. Liver protection
Ye chrysanthemum injection acts externally on human L02 liver cell line for 40 hours, which can promote the proliferation of liver cells; the alcohol extract can inhibit the peroxide in isolated rat liver tissue, increase the activity of glutathione peroxidase in mouse serum, Scavenging oxygen free radicals, with liver protection function.
8. Other functions
Wild chrysanthemum has a significant antipyretic effect on rabbits with endotoxin induced by typhoid vaccine. This product also has anti-venom and anti-cancer effects.
