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Nov 17, 2022

Do you know the efficacy of Scutellaria Extract​?


Part1. What is Scutellaria Extract?

Scutellaria baicalensis extract is a light yellow powder obtained by extracting and drying Scutellaria baicalensis; it has a slight smell and a bitter taste. It can be used not only in medicine but also in cosmetics, and it is a good raw material for functional beauty cosmetics.

 

Part2. The efficacy of Scutellaria Extract

1. Antipyretic and anti-inflammatory:

Traditional Chinese medicine dispatches prescriptions and medicines, and treats syndromes based on syndrome differentiation. Excessive heat syndromes are mostly guided by the treatment principles of those who are hot and cold. Scutellaria baicalensis is cold in nature, so it has a certain effect on the treatment of excess heat syndromes in clinical practice. In recent years, more in-depth research has been carried out on the antipyretic and anti-inflammatory mechanism of Scutellaria baicalensis and its components. Baicalin and baicalein can produce antipyretic and anti-inflammatory effects by interfering with the metabolic pathway of arachidonic acid and inhibiting the activity of cytokines.


Scutellaria Extract2(1)(1)(1)


2.Antimicrobial:

Scutellaria baicalensis has a strong antimicrobial effect, and its water decoction has a broad-spectrum antibacterial effect. In addition, it can resist a variety of fungi, viruses, mycoplasma, chlamydia and other microorganisms. Scutellaria baicalensis and its active ingredients inhibit the growth of bacteria, fungi, and chlamydia, which may be related to the inhibition of ATP synthase, the formation of microbial film and the expression of certain proteins.

3.Scavenging free radicals, anti-oxidation:

Free radicals have strong oxidative properties and can damage the cells and tissues of the body, causing chronic diseases and aging. The molecular structure of flavonoids in Scutellaria baicalensis mostly contains phenolic hydroxyl groups, so it has certain functions of scavenging free radicals and antioxidation. Baicalein and baicalin are effective antioxidants in Scutellaria baicalensis, which have powerful scavenging effects on a variety of free radicals, such as superoxide anion, hydroperoxidase, alkane peroxyl radicals, and hydroxyl radicals. In addition, baicalein and baicalin can effectively inhibit the metabolism of xanthine oxidase to generate oxygen free radicals, and can be used to treat diseases related to free radicals and oxidative stress.

4.Anti-tumor:

With the in-depth research on Scutellaria baicalensis, it has been found that Scutellaria baicalensis has a certain inhibitory effect on various tumor cells. Scutellaria baicalensis has a certain anti-tumor activity and a wide anti-tumor spectrum, and can act on multiple links of tumor cell growth to play an anti-tumor effect.

5.Liver protection, anti-ulcer:

Activity studies have shown that baicalin can protect liver damage, treat chronic hepatitis, and resist liver fibrosis.

6.Anti-ischemia-reperfusion injury:

The cardio-cerebrovascular protective activity of Scutellaria baicalensis is mainly manifested in the protection of myocardial ischemia-reperfusion injury and cerebral ischemia-reperfusion injury, improvement of atherosclerotic lesion progression, lowering blood pressure, antithrombotic and other aspects.

7.Protect neurons:

Modern studies have shown that baicalin and baicalein have protective effects on a variety of neurons, and may become potential drugs for the treatment of neurological diseases such as Parkinson's.

8.Regulating immunity:

The active ingredients in Scutellaria baicalensis have bidirectional regulatory effects of immunosuppression and immune enhancement, and are expected to be used in the treatment of various allergic diseases.

Other Scutellaria baicalensis extracts also have the effects of treating and preventing diabetes and its complications, protecting human periodontal ligament fibroblasts, anti-parasites, anti-tocolysis, inhibiting lipid accumulation, and anti-photoaging.



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