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1.What is Glabridin?
Glabridin powder is a natural substance with excellent whitening effect, which can only be extracted from the rare licorice glabra. In 1000kg of licorice, only 100g of glabridin can be obtained. The scarcity and difficulty of extraction make 1 gram of glabridin equivalent to 1 gram of physical gold. By detecting the IC50 value of inhibiting melanin. Studies have found that the whitening effect of glabridin is 232 times that of vitamin C. At the same time, glabridin also has anti-inflammatory and anti-oxidative effects, and has passed the inspection of the US FDA, and is a safe ingredient. Does not cause skin irritation.
Glabridin, also known as glabridin, is a natural skin care ingredient extracted from a plant called licorice glabra. It is popular because it is a recognized whitening ingredient. Glabridin was originally discovered and extracted by Maruzen, a Japanese skin research institute. It has been verified by scientific experiments that glabridin can effectively inhibit the conversion process of dopa to melanin, thereby reducing the formation of sunburn and the retention of melanin on the skin surface. The above is the principle of licorice whitening.
The gold-level skin care appearance and price make Licorice Glycyrrhiza Glabridin a recognized "whitening gold". Glabridin is a flavonoid extracted from a precious plant called Glycyrrhizae glabra. Glabridin (whitening gold) can penetrate deep into the skin and maintain high activity, whitening and highly effective anti-oxidation. Effectively inhibit the activity of various enzymes in the process of melanin production, especially inhibit the activity of tyrosinase, thereby inhibiting the production of melanin. At the same time, it also has the effect of preventing rough skin, anti-inflammation and antibacterial. Glabridin is currently a whitening ingredient with good curative effect and comprehensive functions, with obvious effect and good safety.
Glabridin is used as the main functional ingredient in big-name whitening cosmetics, such as Lancome, Dior, Sonia Rykiel, and Chanel.
The gold title of glabridin has another meaning, that is, glabridin has a gold-level effect among many whitening ingredients-the experimental detection of melanin inhibition IC50 value found that glabridin's inhibitory effect on melanin is 232 times that of vitamin C.
Glabridin is the hottest whitening ingredient at the moment. With its incomparable whitening effect, it will become a hot trend in the skin care industry. It can be said that with a bottle of Glabridin skin care products with sufficient content, the whitening effect can match several bottles of ordinary skin care products.

|
Product name |
Glabridin |
|
Extract source |
Dry roots and rhizomes of Glycyrrhiza glabra |
|
Extraction Solvent |
Water/Ethyl alcohol |
|
Appearance |
Brown powder or white powder |
|
Solubility |
Glabridin is insoluble in water, but soluble in organic solvents such as butanediol and propylene glycol |
|
Identification |
TLC , HPLC |
|
Sulphated Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of Glabridin (HPLC test, percent, Standard in House) |
Min. 98.0% |
|
Residual Solvents |
|
|
- N-hexane |
NMT 290 PPM |
|
- Methanol |
NMT 3000 PPM |
|
- Acetone |
NMT 5000 PPM |
|
- Ethyl Acetate |
NMT 5000 PPM |
|
- Ethanol |
NMT 5000 PPM |
|
Pesticide Residues |
|
|
- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT) |
NMT 0.05 PPM |
|
- Aldrin, Endrin, Dieldrin |
NMT 0.01 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China |
|
Shelf life |
24 months |
1.1 Chemical & Physical Properties
|
CAS Number |
59870-68-7 |
Molecular Weight |
324.37 |
|
Density |
1.3±0.1 g/cm3 |
Boiling Point |
518.6±50.0 °C at 760 mmHg |
|
Molecular Formula |
C20H20O4 |
Melting Point |
154-155ºC |
|
Common Name |
Glabridin |
Flash Point |
267.4±30.1 °C |

1.2 Introduction to extraction sources
In the clean and simple Hokkaido, the industrious girls in the village farm in the mountains and forests, in the rain or shine, all year round. But to my surprise, their skin, whether on their hands or faces, was clean and fair without any trace of being baptized by the hot sun. It was later discovered that when the girls came back from farming every day, they would mash a whole plant they had collected, soak it in water and wash their faces and hands. Over time, the skin is not afraid of the sun and remains fair. And this plant is licorice glabra.
Glycyrrhiza glabra L. is a perennial herb, mainly distributed in northern Xinjiang, Qinghai, Gansu and other provinces and regions. It is rich in resources, with wild and artificial cultivation bases and large reserves. Its main components are triterpenoid saponins such as glycyrrhizinic acid, glycyrrhetinic acid and glycyrrhizin, and flavonoids such as liquiritigenin and isoliquiritigenin.

2.Benefits and Application
Health Benefits
According to the latest pharmacological experiments, Glabridin has the following effects on health:
Whitening effect
Body tyrosinase is an essential enzyme that can regularly produce melanin and turn the skin or eyes from brown to black, so inhibiting the activity of tyrosinase can inhibit the production of melanin. Experiments have found that glabridin has an inhibitory effect on tyrosinase and melanin, which is 232 times that of vitamin C, the king of whitening.
Antioxidant effect
Glabridin can reduce the generation of oxidation products of low-density lipoprotein, reduce the adhesion of oxidized liposomes on the inner wall of capillaries, and keep the capillaries unimpeded, so that the peripheral cells of the skin can maintain normal vitality.

Anti-inflammatory effect
Glabridin can reduce inflammation caused by ultraviolet radiation (sun exposure), chemical stimulation, etc., and reduce cell death caused by inflammation; At the same time, it can reduce the collapse of inner skin cells caused by endotoxicity of cells after inflammatory death, and play an anti-aging effect and Reduces hyperpigmentation caused by inflammation.

Antibacterial effect
3.Cosmetic application
Glabridin has excellent anti-inflammatory, anti-oxidative and anti-melanin formation effects, so it is used as an ingredient in various cosmetics and medical care products (such as face cream, lotion, shower gel, etc.). It can be made into a whitening cream, and there are already such patented products on the market.
Dosage: To achieve a whitening effect in cosmetics, the patent recommended dosage is 0.001-3% Graffdin, ideally 0.001-1%. Add glycerol to 1:10 at lower temperature. Topical grabridin can inhibit the formation of melanin. Significant inhibitory effect on tyrosinase can prevent skin tanning, freckles, and sunburn. The recommended dosage is 0.0007-0.05%. Studies have shown that 0.05% Gravudine, 0.3% Aloe Vera Powder, 1% Niacinamide and 1% AA2G can inhibit 98.97% of melatonin lipoase. 0.5%.
Chinese scientists have also studied the preparation of Graff Dinglifusone and its application in beauty cosmetics. The results showed that Grafdin rifampicin can be successfully prepared using the rifampicin model and preparation technique. The phospholipid bilayer membrane of Grafdin rifampicin is similar to the biological membrane, and it is easy to fuse with the biological membrane, which promotes the penetration of the functional ingredients into the biological membrane, so that the functional ingredients can effectively pass through the skin barrier, and the biological membrane is higher. It has a positive effect on improving auxiliary effects such as skin whitening and freckle removal.
4.Market outlook
The most common glabridin 40% Glabridin sold in the market is mainly composed of licorice flavonoids, which is brown or white powder. American Sabinsa is one of the earliest producers of glabridin in the world. Because 40% Glabridin is extracted from licorice, it is also called licorice flavonoids, and it is the active ingredient with the best whitening effect of licorice. Known as "whitening gold" in the cosmetics industry in the world, 40% Glabridin is added in an amount of 0.05-0.2%, dissolved with PEG-400 at a ratio of 1:8, and added at low temperature in the final stage of the formula.
5.Extraction process of Glabridin powder

6. Why choose Kintai

7.Production Process

8.Kintai-Factory

9.Kintai R&D room

10.Parcel delivery

11.Contact us
★If you want to get high quality Glabridin powder, please feel free to contact us at sales@kintaibio.com or feedback in next page.
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