Ampelopsis Grossedentata Extract

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of ampelopsis grossedentata extract in China. Please feel free to wholesale high quality ampelopsis grossedentata extract for sale here from our factory. For price consultation, contact us.

Ampelopsis grossedentata extract produced by Kintai is extracted from natural plants. The leaves of this plant are rich in a variety of active ingredients, especially dihydromyricetin (DHM). As a major manufacturer of Ampelopsis grossedentata extract, in addition to producing the main specification of 98% DHM, we also use advanced encapsulation technology to produce water-soluble dihydromyricetin to expand the application range of this ingredient in skin care products.

Our water-soluble product can be completely dissolved in water to form a clear yellow liquid, which will not produce precipitation even if it is left for a long time. Its application in skin care products has significant versatility, which can not only resist aging, anti-inflammatory, and whitening but also provide comprehensive antioxidant protection for the skin.

Ampelopsis grossedentata extract is rich in a variety of flavonoids, polyphenols, polysaccharides, amino acids and trace elements, among which dihydromyricetin is the main one, accounting for about 80% of flavonoid compounds. Low-content extracts contain other active substances such as quercetin, rutin, naringenin, etc., so they have strong antioxidant and anti-inflammatory effects.

Physical and chemical properties:

• Thermal stability: Stable below 100°C, suitable for use in cosmetics. It performs better under neutral and slightly acidic conditions, and oxidation reactions may occur above 100°C.
• Storage conditions: Avoid light and high temperature. It is recommended to store in a low-temperature and dry environment to ensure its activity.

1. Anti-aging and anti-oxidation
Dihydromyricetin has excellent performance in the ability to fight free radicals and can effectively remove DPPH free radicals. Its antioxidant effect is better than common antioxidants such as BHA and BHT. In addition, its antioxidant capacity in oleic acid is close to TBHQ, which is significantly higher than other traditional antioxidants.

Experimental studies have shown that it can inhibit the activity of rapamycin target protein complex (mTOR) by regulating the classic autophagy signaling pathway, thereby promoting the cell autophagy process. This effect can remove waste and free radicals in aging cells and maintain cell vitality, thereby achieving the purpose of anti-aging.

In addition, in our independent research, it was found that it significantly reduced the biological age of skin cells by reducing DNA methylation, thereby improving skin elasticity and reducing wrinkles. Dihydromyricetin affects DNA methylation and histone modification by inhibiting the activity of DNMT1 enzyme and upregulating epigenetic regulatory factors such as TET2 and KDM5C, helping to restore the characteristics of young skin.

2. Anti-inflammatory and antibacterial effects
Kintai Ampelopsis grossedentata extract significantly reduces the expression of inflammatory cytokines (such as TNF, IL-1, and IL-6) by inhibiting the NF-κB signaling pathway, thereby reducing immune cell aggregation and inflammatory response. At the same time, it can also remove reactive oxygen species in cells, reduce oxidative stress, and further protect skin cells from damage.

In addition, it can inhibit ATP synthesis and cell membrane function by interfering with the metabolic process of microorganisms, making it impossible for cells to reproduce normally. This broad antibacterial property makes it an ideal skin care ingredient, especially for sensitive skin that is prone to infection.

3. Whitening effect
The dihydromyricetin in this extract has a strong inhibitory effect on tyrosinase, especially at a mass concentration of 0.8 mg/mL, the inhibition rates of monophenolase and diphenolase reached 95.87% and 69.01%, respectively. By inhibiting tyrosinase activity, it can effectively inhibit the production of melanin and achieve a whitening effect.

4. Reduce scars and anti-fibrosis
Long-term inflammation can lead to excessive proliferation of skin fibroblasts and accumulation of ECM (extracellular matrix), which in turn leads to the formation of hypertrophic scars. Dihydromyricetin can effectively reduce the occurrence of fibrosis by selectively inhibiting the TGF-β/Smad2/3 signaling pathway, helping to repair damaged skin and reduce scar formation.

The main effects of this ingredient in skin care products include anti-oxidation, anti-inflammatory, antibacterial, whitening, and skin tightening. By conditioning and repairing the skin, it can not only reduce wrinkles and fine lines, but also enhance the elasticity and firmness of the skin.

Recommended dosage:
Anti-free radical aging: 0.05%-0.3%
Anti-inflammatory and anti-allergic: 0.1%-0.5%
Whitening effect: 1.0%-3.0%

Effects of use:

• Firming skin: Dihydromyricetin can reduce enlarged pores and tighten the skin by fighting free radicals and inhibiting collagenase to prevent collagen degradation.
• Enhancing skin activity: By inhibiting the apoptosis pathway, it prolongs cell life and keeps the skin young.
• Eliminate free radicals: DHM can significantly remove free radicals and protect the skin from environmental factors and pollution.

We have verified through many experiments that this ingredient has no obvious toxicity or allergenicity when used externally, and is very suitable for use in various types of skin care products. Especially for the conditioning of sensitive skin and acne skin, as a natural ingredient, it can gently improve the skin condition.

★As a natural and effective skincare ingredient, Ampelopsis grossedentata extract has broad application prospects in the field of skin care products due to its powerful antioxidant, anti-inflammatory, antibacterial, whitening and other effects. We are always committed to providing customers with high-quality, scientifically verified natural skincare ingredients to help you create an excellent product experience. If you have any needs or questions about our Ampelopsis grossedentata extract, please feel free to contact us at sales@kintaibio.com or feedback on the next page.

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