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Natural Glutathione Powder

Natural Glutathione Powder

Plant Source: Tripeptide containing sulfhydryl group and bound by glutamic acid, cysteine and glycine
Specification: 98%
Test Method: HPLC
CAS Registry No of Glutathione: 70-18-8
Appearance: White crystalline powder
Certifications: ISO, HACCP, HALAL, KOSHER, Technical Invention Patent Certificate
MOQ: 1KG;
Sample: Free sample available
Production Capacity: 2000KG/month
Delivery Time: Delivery within one day from warehouse
Shelf Life: Two years
Payment: Multiple terms acceptable like T/T, LC, DA
Company Advantage:Kintai mainly focuses on the production of high content plant extracts and pharmaceutical intermediates all the year round.
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Product Introduction

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of natural glutathione powder in China. Please feel free to wholesale high quality natural glutathione powder for sale here from our factory. For price consultation, contact us.

 

1. Introduction of Glutathione

 

Natural glutathione powder is a tripeptide containing glutathione, bladder ammonia and glutathione in combination with methathione, which has antioxidant and comprehensive detoxification functions. The ester of bladder ammonia is the active group of glutathione (therefore glutathione is often abbreviated as G-SH). It can easily be combined with some drugs (e.g., pyrolysis) and toxins (e.g., free radicals, iodic acetic acid, mustard, lead, mercury, arsenic, etc., heavy metals), and has a comprehensive detoxifying effect cells) can participate in biotransformation by converting harmful toxins in the body into harmless substances and excreting them from the body. Glutathione also contributes to the maintenance of normal function of the immune system.
Glutathione contributes to the maintenance of normal function of the immune system and has an antioxidant and comprehensive detoxifying effect.Cytogroup in bladder ammonia is its active group (commonly abbreviated as G-SH), which can be easily combined with some drugs and toxins.Glutathione is widely used in the fields of medicine and health care.
There are two forms of glutathione: reduced (G-SH) and oxidized (G-S-S-G) forms. Under physiological conditions, the reduced form, bladder blood predominates, and its coenzyme can provide NADPH for the bypass metabolism of phosphate penthrone.
Glutathione (GSH) is glutathione, glutathione and glutathione-bound tripeptide that contains cytophytes. It has antioxidant and extensive detoxifying activities. Abbreviated as), it is easy with some drugs (eg, acetaminophenol) and toxins (eg, free radicals, iodic acetic acid, mustard, lead, mercury, arsenic and other heavy metals) and has a comprehensive detoxification effect, therefore glutathione (especially glutathione in hepatocytes) can participate in biotransformation, Convert harmful toxins in the body into harmless substances and excrete them, helping to maintain the normal function of the immune system.

natural-glutathione-powder

Product name

Glutathione

Extract source

Tripeptide containing sulfhydryl group and bound by glutamic acid, cysteine and glycine

Extraction Solvent

Water/Ethyl alcohol

Appearance

White crystalline powder

Solubility

Soluble in water, dilute alcohol, liquid ammonia and methyl formamide, but insoluble in alcohol, ether and acetone

Identification

TLC , HPLC

Sulphated Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay of Glutathione (HPLC test, percent, Standard in House)

Min. 98.0%

Microbiological Quality (Total viable aerobic count)

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Shelf life

2 years if sealed and store away from direct sun light.

 

 

2.Content distribution

 

Glutathione exists in plants and animals. The content in baker's yeast, wheat germ and animal liver is very high, up to 100~1000 mg/100g, 26~34 mg/100g in human blood, 58~73 mg/100g in chicken blood, 10~15 mg/100g in pig blood, high in tomatoes, pineapples and cucumbers (12~33 mg/100g), and low in sweet potatoes, mung bean sprouts, onions and shiitake mushrooms (0.06~0.7 mg/100g).

Foods-Containing-Glutathione

 

3. Physiological function

 

(1) Remove toxic effects;

(2) redox agent;

(3) Protect the activity of mercaptolase: keep SH, the active group of mercaptolase, in a reduced state;

(4) Maintain the stability of erythrocyte membrane structure: eliminate the destruction of oxidants on erythrocyte membrane structure.

 

 

4.principle

 

Strengthens the body's immune system Immunological activity in your body involves multiplying unblocked lymphocytes and antibody production required to maintain normal levels of glutathione within lymphocytes.

Antioxidant and Free Radical Scavenger Glutathione has a protective effect on the environment from harmful effects, including bacterial, viral pollutants and free radicals.

Regulates Other Antioxidants - Glutathione Other important antioxidants like vitamins C and E cannot do their job adequately to protect your body from disease.

 

Glutathione is a small-molecular peptide substance that contains a metato group and has two important antioxidant and comprehensive detoxifying activities. Glutathione is a tripeptide composed of glutathione, bladder, and glutathione. The metho group of bladder ammonia is its active group (therefore, bladder gluten). is generally abbreviated as G-SH.) It has a comprehensive detoxification effect in combination with iodoethyl acid, mustard gas (a type of toxic gas), lead, mercury, arsenic and other heavy metal salts. Glutathione (especially glutathione in liver cells) ) has very important physiological functions, including integrating detoxification. It can participate in biotransformation by binding to certain drugs (e.g., blisters) and toxins (e.g., free radicals, heavy metals), thus of harmful toxins can be converted into harmless substances and excreted out of the body.
There are two forms of glutathione, the reduced form (G-SH) and the oxidized form (GSSG). Under physiological conditions, glutathione, the reduced form, dominates. Glutatide reductase catalyzes the conversion between the two forms. The coenzyme for this enzyme is NADPH, which is provided for glycophosphate bypass metabolism.

How-Glutathione-Works-in-the-Body

 

 

5. Physical and chemical properties

 

CAS Number 70-18-8 Molecular Weight 307.323
Density 1.4±0.1 g/cm3 Boiling Point 754.5±60.0 °C at 760 mmHg
Molecular Formula C10H17N3O6S Melting Point 182-192ºC
Common Name Glutathione Flash Point 410.1±32.9 °C

natural glutathione powder

 

 

 
6. Benefits and Application

 

The main active ingredients of Glutathione, which have many unique effects as below:

6.1 Protect the liver and treat various liver diseases.

6.2 Treat tumors and reduce the side effects of chemotherapy and radiation therapy.

6.3 As an antidote, glutathione can combine with toxic compounds, heavy metal ions or carcinogens entering the human body, and promote their excretion from the body to play a detoxification role; it is used for acrylonitrile, fluoride, carbon monoxide, heavy metal and organic solvent poisoning treatment etc.

6.4 Treatment of ophthalmic diseases, in particular for the treatment of cataracts.

6.5 Glutathione can correct the imbalance of acetylcholine and cholinesterase, and play anti-allergic effect.

6.6 Glutathione can prevent skin aging and pigmentation, reduce melanin formation, improve skin antioxidant capacity, and make skin shiny.

How-natural-glutathione-powder-works-on-the-skin

6.7 Recent studies have pointed out that glutathione may also have the effect of inhibiting the AIDS virus.

Application of Natural glutathione powder

(1) Clinical drugs: Glutathione drugs are widely used in clinic. In addition to the use of its sulfhydryl group to chelate heavy metals, fluoride, mustard gas and other toxins, it is also used in hepatitis, hemolytic diseases, keratitis, cataract and retinal diseases, as a treatment or auxiliary treatment drug. In recent years, Western scientists, especially Japanese scholars, have found that glutathione has the function of inhibiting HIV.

The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti allergic role, prevent skin aging and pigmentation, reduce the formation of melanin, Antioxidant, make skin more elastic. In addition, GSH also plays a very good role in the treatment of ophthalmopathy and the improvement of sexual function.

(2) Antioxidant: As an important antioxidant in the body, glutathione can eliminate free radicals in the body; Because GSH itself is easily oxidized by some substances, it can protect the sulfhydryl group in many proteins, enzymes and other molecules from being oxidized by harmful substances in the body, so as to ensure the normal physiological functions of proteins, enzymes and other molecules; The content of glutathione in human erythrocyte is very high, which is of great significance to protect the sulfhydryl group of protein on erythrocyte membrane from being reduced and prevent hemolysis.

(3) Food additives:

a. Added to flour products, it can play a reducing role, strengthen food nutrition and other functions.

b. When added to yogurt and infant food, it is equivalent to vitamin C and can act as a stabilizer.

c. Mix it in the fish cake to prevent the color from deepening.

d. When added to meat products, cheese and other foods, it has the effect of enhancing flavor.

Application of natural glutathione powder

 

 

7.Glutathione detection

 

HPLC
Principle: High performance liquid chromatography is a process of continuous separation due to the differences in the distribution coefficient, affinity, molecular size, and adsorption capacity of solutes between the fixed phase and the mobile phase.
Steps:
① Chromatographic conditions
Chromatographic column: Kromasil C18 column (4.6 mm × 250 mm, 5 μm).
Mobile phase: mixed solution of sodium dihydrogen phosphate and sodium octane sulfonate (sodium dihydrogen phosphate 3.0 g, sodium octane sulfonate 1.0 g, add water to dissolve and set the volume to 500 mL, adjust the pH of the solution to 3 with phosphoric acid): acetonitrile = 96:4 (volume ratio).
Detection wavelength: 210 nm, flow rate 0.8 mL/min, column temperature 30°C, injection volume 10 μL.
②Preparation of standard solution
Accurately weigh an appropriate amount of glutathione standard substance, dissolve it in a volumetric flask with deionized water, mix evenly, and constant volume to prepare 25 μg/mL, 50 μg/mL, 100 Vg/mL, 200 μg/mL, 400 μg/mL μg/mL, 800 μg/mL serial concentration sample solution, as the standard solution.
③Sample preparation
Accurately weigh the glutathione sample, add deionized water, mix well, and make a sample solution with a concentration of 25-800 μg/mL as the analysis solution.
④ Draw a standard curve
Draw 10 μL of the prepared glutathione standard solution and inject it into the sample for determination, draw the standard curve based on the concentration and peak area of glutathione, and obtain the regression equation of the curve according to the standard curve. The change of the peak area should have a linear relationship with the mass concentration of glutathione, and its fitting degree should be above 0.9995.
⑤Determination of samples
Take 10 μL of the glutathione sample analysis solution, inject and measure it with a high-performance liquid chromatograph, obtain the peak area of the sample solution, and calculate the glutathione content according to the regression equation.

 

 

8.Extraction process of Glutathione

 

Extraction process

 

 

9. Why choose Kintai

Why choose Kintai.jpg

 

 

10.Kintai manufacturing base

 

Kintai manufacturing base

 

 

11Production Process

 

production process

 

 

12.Our R&D center

 

★If you want to get high quality Natural glutathione powder, please feel free to contact us at cheney@kintaibio.com or feedback in next page.

 

 

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