Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of pure alpha arbutin powder in China. Please feel free to wholesale high quality pure alpha arbutin powder for sale here from our factory. For price consultation, contact us.
alpha arbutin powder supplier
Arbutin is a hydroquinone-derived glycoside compound, which is divided into β-arbutin and α-arbutin according to the different configurations of the glycosidic bond. Arbutin is widely used in the cosmetics field as a safe and stable whitening agent. It is also used in the medical field because of its pharmacological activities such as antioxidant, antibacterial, anti-inflammatory and anti-tumor.
Kintai mainly produces arbutin by plant extraction, and the extraction source is Bearberry Plant. Our main product is 98% Pure Alpha Arbutin Powder. In recent years, we have optimized the extraction process, mainly using plant transformation and biosynthesis for large-scale production, thus solving the problem of low yield.
Extraction source Bearberry plant
Main production process improvement: plant transformation method
The kintai R&D team obtains these natural products β-arbutin by extracting from Bearberry Plant, and then transforming it to obtain α-arbutin. In addition, in 2023, we obtain α-arbutin by culturing cells, tissues or organs of Plant in vitro and transforming the added substrate as a biocatalyst. This plant transformation technology makes our α-arbutin less susceptible to the impact of climate, environment, and raw material supply, and has therefore become a major method for our company to biosynthesize arbutin.
Synthesis of α-arbutin by plant conversion
Pure Alpha Arbutin Powder feature
★ Quickly whitens & brightens the skin, the whitening effect is stronger than β-arbutin, suitable for all skin types.
★ Effectively lighten spots (age spots, liver spots, post-sun pigmentation, etc.).
★Protects the skin and reduces skin damage caused by UV rays.
★Safe, less dosage, lower cost.
★It has good stability and is not affected by temperature, light, etc. in the formula.
COA OF Pure Alpha Arbutin Powder
Safe use and supervision of arbutin
On August 22, 2023, the China National Medical Products Administration promulgated the "Test Methods for Four Raw Materials Including α-Arbutin in Cosmetics", which was officially implemented on March 1, 2024. The addition standard of arbutin is clarified: the addition amount of α-arbutin is usually between 0.1%-1.0%, and the addition amount of α-arbutin in some whitening and freckle removal products is between 1.0%-3.0%; the addition amount of β-arbutin is generally between 1%-10%.
The European Union Scientific Committee on Consumer Safety (SCCS) believes that the maximum safe use concentration of α-arbutin in face creams is 2%, the maximum safe use concentration of α-arbutin in body lotions is 0.5%; the maximum safe use concentration of β-arbutin in face creams is 7%.
arbutin powder benefits
1 alpha arbutin powder for skin whitening
Related studies treated B16 F10 cells by changing the culture method to stimulate stimulate the activity of tyrosinase, and finally established a cell model with high melanin content. The experimental results show that compared with Pure Alpha Arbutin Powder as a single component, a-arbutin is and a combination of multiple active ingredients have inhibitory effects on tyrosinase activity The effect is significantly improved by 17%, and the melanin content is suppressed and reduced by 30%. At the same time, through spots In the horsefish model, it was verified that a-arbutin can significantly inhibit zebrafish at low concentrations. Expression of melanin, melanin production is almost unobservable at high concentrations.
2 Photodamage protection
To determine the protective effect of a-arbutin on HaCaT cells after UVA irradiation Whether the protective effect is related to its inhibition of apoptosis, we used Annexin Effects of V-FITC and P| double staining methods on treatment with different concentrations of a-arbutin Apoptosis detection of HaCaT cells. The results showed that compared with the blank group, UVA irradiation irradiation significantly increased the cell apoptosis rate. Compared with the model group, different concentrations of Pure Alpha Arbutin Powder for Photodamage Protection The apoptosis rate of HaCaT cells was significantly reduced after the action of glycosides (25, 50, 100umol·L-1). decreased, and showed a certain dose dependence. Therefore, a-arbutin may inhibit The apoptosis rate of HaCaT cells thus plays a protective role against light damage.
alpha arbutin powder uses
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