95% Mangiferin powder Supplier
As leading manufacturers of Mangiferin, kintaibio® offers high-quality Mangiferin powder, a powerful natural polyphenol extracted from mango leaves (Mangiferina). Our sustainable extraction process uses patented technology, ensuring top-notch quality while keeping costs low. With continuous investment in R&D, we refine our processes to offer consistent, pure products at competitive prices.
Our Mangiferin Powder consistently achieves ≥95% HPLC purity and offers potent antioxidant and anti-inflammatory properties. It is scientifically linked to benefits such as blood sugar management, inflammation reduction, heart health support, and immune system boosting. The powder is widely used in pharmaceuticals, dietary supplements, and skincare formulations.
kintaibio® provides a strong price-to-performance ratio for Mangiferin powder, leveraging our efficient production process and patented technology to offer high-purity, reliable raw materials. Our ingredients help improve the effectiveness, safety, and market competitiveness of your products. Partnering with us ensures access to consistent, high-quality plant extracts, supporting your product's added value and long-term success.
KINTAI's Patent on Mangiferin
Determination method of 95% mangiferin powder
A.1 General provisions
The reagents and water used in this standard refer to analytical reagents and experimental water in compliance with the provisions of GB/T 6682, unless otherwise specified. The solution used in the experiment refers to the aqueous solution when it is not indicated which solvent is used for preparation.
A.2 Mangiferin
A.2.1 Method summary
After the sample was dissolved in 50% MeOH, it was determined by high performance liquid chromatography, and the content of mangiferin in the sample was calculated by the external standard method with mangiferin as the reference substance.
A.2.2 Instruments and materials
A.2.2.1 Analytical balance, the sensitivity is 0.01mg.
A.2.2.2 High performance liquid chromatography.
A.2.2.3 Ultrasonic cleaner.
A.2.2.4 0.45μm organic phase microporous membrane.
A.2.3 Reagents and solutions
A.2.3.1 Reference substance: mangiferin, purity ≥ 98.0%.
A.2.3.2 Methanol, analytically pure.
A.2.3.3 Acetonitrile, chromatographically pure.
A.2.3.4 Phosphoric acid, analytically pure
A.2.3.5 Water
A.2.4 Chromatographic conditions
A2.4.1 Chromatographic column: C18 reverse phase chromatographic column, 250mm×4.6mm, particle size 5μm or other equivalent chromatographic column.
A2.4.2 Mobile phase: ACN-0.4%H3PO4 (20:80)
A2.4.3 Flow rate: 1ml/min
A2.4.4 Detection wavelength: 258nm
A2.4.5 Column temperature: 30°C
A2.4.6 Injection volume: 10μL
A.2.5 Operation method
A.2.5.1 Preparation of reference substance solution
Weigh about 10mg of the reference substance, weigh it accurately, put it in a 50mL volumetric flask, dissolve it with 50% MeOH, and treat it with ultrasound (250W, 40KHz) for 5 minutes, let it cool, and dilute it to the mark with 50% MeOH, shake well, Filter through a 0.45um microporous membrane, take the filtrate, and set aside.
A.2.5.2 Sample solution preparation
Weigh about 10 mg of the sample, weigh it accurately, put it in a 50 mL volumetric flask, add an appropriate amount of 50% MeOH, treat it with ultrasound (250W, 40KHz) for 5 minutes, and dilute to the mark with 50% MeOH, shake well, and filter through a 0.45um microporous filter Film, that is.
A.2.5.3 Determination method
Precisely draw 10uL of the reference substance solution and 10uL of the sample solution respectively, inject them into the liquid chromatograph, measure and record the chromatograms.
A.2.6 Calculation of results
Calculation of sample content by external standard method:
In the formula:
W1 - content of reference substance
W2--sample content
S1-- peak area of reference substance
S2--sample peak area
m1--the weighing amount of the reference substance, in milligrams (mg)
m2--sample weight, in milligrams (mg)
Extract process of 95% mango leaves extract (Mangiferin)
The benefits of mangiferin in liver protection.
Mangiferin powder is a natural plant component extracted from the leaves of the mango tree. The role of mango glucoside in liver protection is mainly manifested in reducing liver fat content, antioxidant, regulating lipid metabolism and inhibiting inflammatory response, which can effectively protect liver health and prevent and alleviate liver diseases, and is a natural and safe nutrient for liver protection. Studies have shown that mango leaf extract has excellent liver protective effects.
a. Mango leaf extract can reduce liver fat content and reduce fatty liver lesions, thus protecting and restoring liver cell function, and reducing and preventing liver diseases.
b. Mango leaf extract has good antioxidant properties, which can scavenge free radicals in the body, reduce the damage to liver cells from oxidative stress, and protect liver cells from oxidative stress.
c. Mango leaf extract also has various benefits such as regulating lipid metabolism, inhibiting inflammatory response, and lowering blood lipids, all of which have positive effects on liver health.
Reference:https://www.sciencedirect.com/science/article/pii/S0753332219314763
The benefits of mangiferin in the treatment of bronchitis.
Mangiferin has a variety of pharmacological properties. In recent years, studies have shown that Mangiferin has positive effects in the treatment of bronchitis.
a. Mangiferin has good anti-inflammatory and antioxidant properties, which can reduce the symptoms of bronchitis patients and reduce the damage to lung tissues caused by oxidative stress, thus promoting the recovery and healing of bronchitis.
b. Mangiferin also has a variety of analgesic, antibacterial and immunomodulatory effects, which can relieve patients from discomfort and complications caused by bronchitis.
c. Mangiferin also has the ability to improve lung function, stabilize respiratory rate and reduce airway resistance, thus helping patients with bronchitis to improve their breathing capacity and promote lung health recovery.
d. The effects of Mangiferin in the treatment of bronchitis are mainly manifested as anti-inflammatory, antioxidant, analgesic, antibacterial, immunomodulatory, improving lung function and other properties, which can effectively relieve symptoms, promote healing and prevent complications, and is a more ideal natural pharmaceutical ingredient.
Other Benefits
a.Blood sugar lowering effect
Mangiferin powder can lower blood sugar level and enhance the effect of insulin, which has certain therapeutic effect on diabetes and other related metabolic diseases.
b. Antioxidant effect
Mangiferin has good free radical scavenging ability, which can prevent body aging and various diseases.
c. Anti-inflammatory effect
Mangiferin can alleviate inflammatory response, reduce cellular oxidative damage and inflammatory mediator release, which helps to treat inflammation and other related diseases.
References：https://www.sciencedirect.com/science/article/abs/pii/S0278691521000314
d. Antibacterial effect
Mangiferin can inhibit the growth and reproduction of a variety of pathogenic bacteria, and has a certain antibacterial effect.
e. Promote cardiovascular health
Mangiferin is rich in flavonoids, which can lower blood pressure and improve cardiovascular health.
f. Improve immunity
Mangiferin also has the effect of enhancing immunity and promoting physical recovery, which can help people maintain a healthy state.
g. Anti-cancer effect
Mangiferin has the ability to inhibit the proliferation and spread of tumor cells, which can be used in anti-cancer treatment.
References：https://www.sciencedirect.com/science/article/abs/pii/S0278691521000314
Mangiferin produced by KINTAI has been widely used in health care products, food additives, pharmaceuticals, cosmetics, etc. The most common applications include healthcare products, diet foods, cosmetics, etc.
Application in medicals
There are various applications of mangiferin in the field of medicine. The following are some of them:
a. Antioxidant: mangiferin is a potent antioxidant that prevents oxidative damage to body tissues by free radicals. It helps to reduce environmental stress and chemical damage.
b. Immune system booster: mangiferin strengthens the body's immune system and improves the body's resistance. It prevents infections and diseases and enhances the body's response to vaccines.
c. Anti-cancer agent: mangiferin has been shown to have preventive and curative effects on many types of cancer. It inhibits the growth of cancer cells and enhances the effects of chemotherapy and radiotherapy.
d. Analgesic: mangiferin relieves pain and inflammation, it reduces arthritis and muscle soreness, and helps with tissue repair.
e. Hypotensive agent: mangiferin can help lower blood pressure and prevent cardiovascular disease. It promotes blood flow and directs nutrients and oxygen into the body for better health.
Mangiferin has many applications in medicine, including immune system enhancement, anti-cancer, antioxidant, analgesic, and blood pressure lowering. Especially in the prevention and treatment of cancer, the application of mangiferin is very promising.
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