Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of pueraria lobata root extract in China. Please feel free to wholesale high quality pueraria lobata root extract for sale here from our factory. For price consultation, contact us.
Pueraria Lobata Root Extract Factory
As a leading supplier of standardized botanical extracts, kintaibio® provides a comprehensive specification of Pueraria lobata root extracts. Our products are manufactured under cGMP, ISO 22000, ISO 9001, and HACCP certifications, ensuring batch-to-batch consistency for your formulation requirements.
Here are our full specifications: For Pharmaceutical, Nutraceutical & Functional Food Applications
1. High-Purity Puerarin Isolates
Pharmaceutical intermediates for cardiovascular/diabetic neuropathy formulations
| Property | Puerarin 98% (HPLC) | Puerarin 95% (HPLC) |
|---|---|---|
| Appearance | Off-white powder | Light yellow powder |
| Purity | 98.0-99.5% (HPLC-UV) | ≥95% |
| Loss on Drying | ≤5.0% | ≤5.0% |
| Heavy Metals | ≤10 ppm | ≤10 ppm |
| Residual Solvents | Meets ICH Q3C guidelines | Meets ICH Q3C guidelines |
| Particle Size | 90% passing 80 mesh | 90% passing 80 mesh |
2. Water-Soluble Pueraria lobata Extract Specifications
| Parameter | Water-Soluble Puerarin 30% | Water-Soluble Puerarin 15% | Test Method |
|---|---|---|---|
| assay( Puerarin) | ≥30.0 % | ≥15.0 % | HPLC (EP 10.0) |
| Solubility Profile | |||
| - Water (25°C) | ≥50 mg/mL (clear solution) | ≥30 mg/mL (clear solution) | USP <1236> |
| - PBS Buffer (pH 7.4) | ≥45 mg/mL | ≥28 mg/mL | Centrifugation 3000rpm/10min |
| - Ethanol (10%) | ≥60 mg/mL | ≥35 mg/mL | Visual inspection |
| Carrier System | β-cyclodextrin complexation (1:2.5 molar ratio) | β-cyclodextrin + natural phospholipids | NMR validation |
| Physical Properties | |||
| - Appearance | Brown powder | Brown powder | Visual |
| - Particle Size | D90 ≤ 80μm | D90 ≤ 100μm | Laser diffraction (ISO 13320) |
| - Bulk Density | 0.45-0.55 g/cm³ | 0.40-0.50 g/cm³ | USP <616> |
| - Moisture Content | ≤ 7.0% | ≤7.0% | Karl Fischer (EP 2.5.12) |
| Microbiological | |||
| - Total Aerobic Count | ≤1,000 CFU/g | ≤1,000 CFU/g | USP <61> |
| - Yeast & Mold | ≤100 CFU/g | ≤100 CFU/g | |
| - E. coli/Salmonella | Absent | Absent | |
All specifications are subject to Certificate of Analysis (COA) with batch-specific data. Customization available for particle size distribution, carrier ratios, and excipient systems.
3. Standardized Flavonoid Complexes:
| Product | Composition | Features |
|---|---|---|
| Puerarin 30% + Total Flavonoids 60% | 30% Puerarin + 60% Total Flavonoids | HPLC-validated, Ratio-optimized for synergistic activity |
| Puerarin 15% + Total Flavonoids 40% | 15% Puerarin + 40% Total Flavonoids | Cost-effective option for dietary supplements |
| Total Kudzu Isoflavones 40-90% (UV) | Puerarin, Daidzin, Genistin, Daidzein | Includes multiple isoflavones (UV-validated) |
4. Daidzein Specialties:
Daidzein 95% (HPLC): White crystalline powder. Melting Point: 315-323°C. Confirmed by NMR & LC-MS.
Daidzein 98%: Pharmaceutical-grade. Residual solvent: ≤0.1% ethanol.
how to use kintaibio® Pueraria Lobata Root Extract ?
1 Puerarin (Purity 98%+, Puerarin 10%–99.5%)
As an isoflavone compound extracted from Pueraria root, kintaibio provides high-purity puerarin, a key raw material for pharmaceutical preparations and cutting-edge scientific research. Our quality standards strictly adhere to the requirements of the Chinese Pharmacopoeia for injectable-grade raw materials (HPLC testing, purity minimum 98%). This product is primarily used in the following areas:
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.771793/full
1.1 Cardiovascular and Cerebrovascular Disease Treatment: As the core ingredient in injections, it is used in the clinical treatment of acute and severe conditions such as coronary heart disease, angina pectoris, and myocardial infarction. Studies have shown that its clinical efficacy can reach 93%–96%, with mechanisms including coronary artery dilation, improved myocardial metabolism, and inhibition of platelet aggregation.
1.2 Ophthalmic and Otological Drugs: Used in the treatment of conditions such as retinal artery/venous occlusion and sudden deafness, clinical reports indicate efficacy rates of 70%–80%, with mechanisms of action related to improved microcirculation, antioxidant activity, and neuroprotection.
1.3 Adjunctive Analgesia: Recent patent research indicates that puerarin can enhance the analgesic effect of opioids by inhibiting microglial activation, reducing drug tolerance and dosage, offering a new strategy for pain management.
2. Daidzein (95%/98% purity)
In addition to puerarin, we also extract daidzein from Pueraria root, a natural phytoestrogen receptor modulator. Our 98% daidzein has a wide range of applications in scientific research, high-end health products, and new drug development:
2.1 Development of functional health products: This product is used in functional foods such as those for alleviating menopausal symptoms and preventing osteoporosis. Its mechanism involves regulating cytokine secretion (e.g., promoting IL-10 and inhibiting IL-6).
2.2 Anti-tumor drug development: As a lead compound, it has demonstrated the potential to induce tumor cell apoptosis and inhibit angiogenesis in vitro and in animal models, and is widely used in anti-tumor drug screening and mechanism studies.
3. Standardized Extracts Puerarin 30% (Total Flavonoids 60%) and Puerarin 15% (Total Flavonoids 40%)
These extracts, while retaining key active ingredients, offer superior industrial economics and are widely used in oral preparations and consumer health products:
- Cardiovascular Oral Preparations: As a raw material for various Chinese patent medicines (such as tablets, capsules, and granules), Pueraria root total flavonoids can provide auxiliary therapeutic benefits by dilating coronary arteries and improving microcirculation.
- Chronic Disease Health Management: Developed for health food products that assist in regulating blood pressure and blood lipids, relevant regulations require a total flavonoid content of no less than 40% (as determined by UV light).
- Hangover and Liver-Protecting Foods: Pueraria root flavonoids can accelerate ethanol metabolism and mitigate alcohol-induced liver damage. They are widely used in hangover-relief chewable tablets, solid beverages, and functional drinks.
5. Water-soluble Puerarin (15%/30%, phosphorylated/sulfonated)
In 2019, we significantly improved the solubility and bioavailability of our Puerarin through chemical modification. Currently, this grade is primarily suitable for the following innovative dosage forms:
- Ready-to-drink functional beverages: These can be used for sports fatigue relief and hangover relief, and our water-soluble technology effectively eliminates sedimentation and mouthfeel issues.
- Oral fast-dissolving films: Suitable for sublingual administration, they avoid first-pass effects and improve drug utilization efficiency.
- Transdermal cosmetic preparations: Their water-soluble properties make them suitable for products such as hydrating injections and microcrystalline patches, enabling the skin delivery of active ingredients.
6. Pueraria Isoflavones (Purity 40%–90%)
This specification retains the various isoflavones naturally present in Pueraria (such as puerarin, daidzein, and genistein), making it suitable for the health and personal care sectors:
- Women's Health Products: Used in the development of natural phytoestrogen replacement therapy products, such as breast enhancement creams and menopausal conditioning capsules.
- Anti-Aging Skincare: Thanks to its antioxidant and photoprotective properties, it is added to serums, creams, and other products to inhibit collagen degradation and delay photoaging.
What can KINTAIBIO® do?
Why choose KINTAIBIO®?
★If you want to PURCHASE high-quality Puerarin Powder, please feel free to contact us at sales@kintaibio.com to provide or feedback on the next page.
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