Ophiopogonis Extract

The main components isolated and identified from Ophiopogon japonicus are steroidal saponins, isoflavones and various types of polysaccharides, primary chromogenones, and so on. More than 20 steroidal saponins have been obtained from different species of Ophiopogon japonicus.

1). Saponins: mainly Ophiopogonin A, B, C, D, B', C', D' (Ophiopogonin A, B, C, D, B', C', D') and glycosides A, B, C, D, E, F, G, H (Glycosides A, B, C, D, E, F, G, H) and so on.

2). Flavonoids: Ophiopogon japonicus and its variants from different origins contain a variety of high isoflavones.

3). Other ingredients: polysaccharides such as Ophiophogonoligosaccharide A, B, C (Ophiophogonoligosaccharide A, B, C), Ophiophogon polysaccharide , etc., as well as β-sitosterol, stigmasterol, borneol Calcium bornyl sulfate., 1-borneol-β-D-glucoside, etc.

1. Antioxidant effect: Studies have shown that the polyphenolic compounds in Ophiopogon japonicus extract powder have obvious antioxidative effects. They scavenge free radicals and reduce damage from oxidative stress. A study found that Ophiopogon japonicus extract powder can reduce malondialdehyde (MDA) content in kidney tissue and increase the activity of antioxidant enzymes SOD and GPx.

2. Anti-inflammatory effect: Taking mouse experiments as an example, the study found that Ophiopogon japonicus extract powder has an anti-inflammatory effect. It can inhibit the inflammatory response induced by lipopolysaccharide and reduce the symptoms of inflammation. This may be related to the anti-inflammatory activity of heteropolyglycosides and polysaccharides in Ophiopogon japonicus extract powder.

3. Improving immune function: Studies have found that Ophiopogon japonicus extract powder can enhance the body's immune function. Taking the mouse experiment as an example, after the administration of Ophiopogon japonicus extract powder, the immune indicators in the mice, such as white blood cell count, lymphocyte count, and serum immunoglobulin (IgG) levels were significantly increased. This may be related to the regulating effect of the polysaccharides in the Ophiopogon japonicus extract powder on the immune system of the body.

4. Anti-tumor effect: Studies have shown that some active ingredients in Ophiopogon japonicus extract powder have anti-tumor activity. One study found that Ophiopogon japonicus extract powder can inhibit the growth and proliferation of tumor cells. Using a mouse experimental model, after administration of Ophiopogon japonicus extract powder, the tumor growth in mice was significantly inhibited, and the tumor inhibition rate was higher than 50%.

References:

(1) Hu, C., et al. (2016). Protective effect of Ophiopogon japonicus polysaccharides on carbon tetrachloride-induced hepatitis in rats. Journal of Food Science and Agriculture, 96(10), 3377-3384
(2) Zhu, Y., et al. (2014). Anti-inflammatory effect of water extract of Ophiopogon japonicus and its constituent: mechanism of action due to inhibition of ERK phosphorylation. Journal of Ethnopharmacology, 153(2), 365- 373
(3) Zhang, B., et al. (2015). Immunomodulatory effect of Ophiopogon japonicus polysaccharides on cyclophosphamide-induced immunosuppression in mice. Journal of Ethnopharmacology, 161, 90-97
(4) Yang, X. W., et al. (2001). Anticancer activity of a new bisdesmosidic triterpenoid saponin from Ophiopogon japonicus. Journal of Asian Natural Products Research, 3(4), 293-297

Medicines and health care products: Ophiopogon japonicus extract powder is often used in medicine and health care products. Ophiopogon japonicus extract contains a variety of active ingredients, such as polysaccharides, mannitol, flavonoids, etc., which have various pharmacological effects such as nourishing blood, lowering blood sugar, anti-oxidation, and inhibiting tumor cell growth. It can be used to regulate immune function and improve liver and kidney functions. , Improve cardiovascular health, improve fatigue resistance, etc.

Food industry: Ophiopogon japonicus extract powder can be used in the food industry to improve the nutritional value and taste of food. Ophiopogon japonicus extract has anti-oxidation, inhibition of food oxidative deterioration, antibacterial, antiseptic, etc. It can be used as an additive for meat products, beverages, dairy products, cakes, and other foods to increase the shelf life of products and improve taste and texture.

Cosmetics and Personal Care Products: Ophiopogon japonicus extract powder can also be used in cosmetics and personal care products.

 Ophiopogon japonicus extract is rich in a variety of active substances, which have moisturizing, anti-inflammatory, anti-oxidant, soothing, and sensitive effects. It can be used in facial masks, face creams, body lotions, shampoos, conditioners, and other products to help improve skin conditions, Regulate skin water and oil balance, and enhance hair health.

Animal feed: Ophiopogon japonicus extract powder can also be used in animal feed to improve animal immunity, resistance, and growth performance, and improve the nutritional value and taste of feed. Polysaccharides and other nutrients in Ophiopogon japonicus extract can improve the digestion and absorption capacity of animals, reduce the occurrence of diseases, and improve the production performance of animals.

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