Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of polygonum cuspidatum extract powder in China. Please feel free to wholesale high quality polygonum cuspidatum extract powder for sale here from our factory. For price consultation, contact us.
Product Details:
1. Introduction of Polygonum cuspidatum extract polydatin
Polydatin powder is the extract of Polygonum cuspidatum. Polygonin, also known as Polygonum cuspidatum extract polydatin, sprucetin, resveratrol glycoside, is extracted from the dry rhizome and root of Polygonum cuspidatum Sieb.et Zucc, is one of the natural active ingredients.
Polygonum cuspidatum extract polydatin is a glycoside substance found in Polygonaceae Polygonum cuspidatum root, Polygonum multiflorum root, Pinaceae Sakhalin spruce bark, Myrtleaceae nuclear tree plant, Angophora cordifolia plant, which has antitussive, expectorant, and antiasthmatic properties , antibacterial, hypolipidemic effect, clinically used to treat cough, asthma and other diseases. The drug polydatin injection can treat myocardial ischemia, cerebral ischemia, shock and other cardiovascular and cerebrovascular diseases. It is the first innovative traditional Chinese medicine to submit a clinical research application in the United States.
Resveratrol glycosides are natural active ingredients mainly found in the rhizomes and roots of Polygonum cuspidatum. Molecular formula C20H22O8, molecular weight: 390.40 White needle-like crystal powder. Soluble in methanol, ethanol, ethyl acetate, alkaline solution, slightly soluble in water. Light stability is relatively poor. Resveratrol glycosides are stilbene compounds with strong biological activity. Resveratrol glycosides are widely distributed in plants with high content. Resveratrol glycosides have been found in at least 70 species of plants. Studies have shown that it has a significant effect on cardiomyocytes, vascular smooth muscle cells, anti-platelet aggregation, and improving microcirculation; in addition, it can also reduce tissue and organ damage caused by various factors, protect liver cells, reduce blood lipids, and resist lipid peroxidation wait.

【Product advantages】
1). Pure natural: The polydatin products extracted by the company are completely made of natural extracts, without adding any chemical drugs or artificial synthetics.
2). High purity: KINTAI's polydatin uses advanced extraction technology to obtain high-purity products. High-purity polydatin can provide better health effects.
3). Factory direct supply
4). Price advantage
5). ODM and OEM service
6). Ship within 3 days

Technical Data Sheet
|
Product name |
Polygonum cuspidatum extract polydatin |
|
Extract source |
Dry rhizome and root of Polygonum cuspidatum |
|
Extraction Solvent |
Water/Ethyl alcohol |
|
Appearance |
White needle crystal powder |
|
Solubility |
Soluble in methanol, ethanol, slightly soluble in water, ethyl acetate. |
|
Identification |
TLC , HPLC |
|
Sulphated Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of 98% Polydatin (HPLC test, percent, Standard in House) |
Min. 98.0% |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Shelf life |
2 years if sealed and store away from direct sun light. |
2.Production process
KINTAI has developed a simple and easy-to-operate process for purifying resveratrol glycosides, and its industrial production is the first in China. This method can not only obtain high-purity (99%) resveratrol glycosides, but also reduce production cost. The product yield is high.
①Water extraction: crush the fresh Polygonum cuspidatum, add saturated lime water to extract for 1.5-2 hours, collect the extract, adjust the acid to pH=7-8, and obtain the crude extract;
②Macroporous resin adsorption: Pass the above crude extract through a macroporous resin column for saturated adsorption, first wash with water to remove impurities, and then elute resveratrol glycosides with ethanol to obtain a resveratrol glycoside eluent;
③Ultrafiltration: the above-mentioned resveratrol glycoside eluate is passed through an ultrafiltration membrane to remove macromolecular impurities to obtain an ultrafiltrate;
④ Concentration: Concentrate the above-mentioned ultrafiltrate under reduced pressure, reclaim ethanol, and obtain extract;
⑤Recrystallization: Recrystallize the above-mentioned extract with ethyl acetate three times to obtain a white needle-like crystal product.

3. Benefits and Application
3.1Polygonum cuspidatum extract polydatin is the extract of Polygonum cuspidatum, which have many unique effects as below:
1). Polygonum cuspidatum extract polydatin has the effects of expelling wind and dampness, dissipating blood stasis, relieving pain, relieving cough and reducing phlegm; it is mainly used for joint pain, damp-heat jaundice, amenorrhea, lumps, water and fire burns, bruises, carbuncles and sores , Cough with a lot of phlegm.
2). It has the effects of strengthening the heart and dilating blood vessels, inhibiting platelet aggregation, regulating blood lipids, relieving cough and asthma, dispelling wind and dampness, dispelling blood stasis, anti-virus, and anti-tumor.
3). Polygonum cuspidatum extract polydatin has a strong antibacterial effect on Trichophyton crimson rubrum and Trichophyton interdigitae that cause stubborn tinea and hibiscus tinea.
4). In clinical application, its extract has a significant antibacterial effect on clinical pathogenic fungi, and its compound formula also has a significant effect of protecting the liver.

3.2 Application
In recent years, there have been more and more studies on the pharmacology and application of Polygonum cuspidatum extract polydatin, and Polygonum cuspidatum extract polydatin and its products are widely used in medicine, beauty, health care, food and other fields.
1) Polygonum cuspidatum extract polydatin is currently reported as a raw material used in the pharmaceutical industry. The drug Polygonum cuspidatum extract polydatin injection can treat myocardial ischemia, cerebral ischemia, shock and other cardiovascular and cerebrovascular diseases; Blood lipid drugs.
2) Polygonum cuspidatum extract polydatin, a polyphenolic phytoalexin, has various physiological and pharmacological effects, including anti-inflammatory and antioxidant activities.

4. Physical and chemical properties
White needle crystal powder. Soluble in ethanol, acetone, slightly soluble in water, ethyl acetate, butyl acetate, etc., almost insoluble in ether, petroleum ether, etc.
| CAS Number | 65914-17-2 | Molecular Weight | 407.391 |
| Density | 1.521 g/cm3 | Boiling Point | 707.7ºC at 760 mmHg |
| Molecular Formula | C20H22O8 | Melting Point | 223-226 °C(lit.) |
| Common Name | (E/Z)-Polygonum cuspidatum extract polydatin | Flash Point | 381.8ºC |

5.Introduction of plant extract source
Polygonum cuspidatum is a perennial shrub-like herb, up to more than 1m. The rhizomes lie underground, woody, yellowish brown, with obvious nodes. The stems are erect, cylindrical, tufted, glabrous, hollow, with scattered purple spots. Leaves alternate; petioles short; stipules sheaths membranous, brown, caducous; leaves broadly ovate or ovate-elliptic, 6-12cm long, 5-9cm wide, apex acute, base round or cuneate, entire, absent hair. Flowers unisexual, dioecious, axillary panicles; pedicel slender, upper part winged; perianth 5-parted, lobes 2 rounds, outer ring 3, enlarged when fruiting, back winged; male flowers stamens 8, female flowers Styles 3, stigma capitate. Achene ellipsoid, with 3 ribs, dark brown. The flowering period is August-September, and the fruiting period is September-October.
(1) Growth environment and distribution area:
The rhizome is used for medicine, and has the effects of activating blood, removing blood stasis, smoothing menstruation, and relieving cough. It is produced in Shaanxi, Gansu, East China, Central China, South China, Sichuan, etc; It is also distributed in North Korea and Japan. Born in hillside thicket, valley, roadside and farmland wetland.
(2) Functional indications:
It dispels wind and dampness, dissipates blood stasis, settles pain, and relieves cough and phlegm. It is used for arthralgia, damp heat, jaundice, amenorrhea, mass disorder, scalding by water and fire, injury by falling and flapping, carbuncle, sore and toxin, cough and phlegm.

6.Extraction process of Polydatin powder

7.Shipping and Packaging Information

7. Why choose Kintai

8.Kintai manufacturing base

9.Our R&D center

10.Contact us
★If you want to get high quality Polydatin powder, we have enough stock.For any other questions or to inquire about custom products and samples, please feel free to contact us at cheney@kintaibio.com or feedback in next page.
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