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Platycodon Grandiflorus Root Extract

Platycodon Grandiflorus Root Extract

Plant Source: Dried root of bellflower
Specification: 20% Total Platycodins , 5:1
Test Method: HPLC
Appearance: Brown powder
Certifications:GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL.
MOQ: 1KG
Sample: Free sample available
Production Capacity: 1000KG/month
Delivery Time: Delivery within one day from warehouse
Shelf Life: 2 years
Payment: Multiple terms acceptable like T/T, LC, DA
Company Advantage: Kintai mainly focuses on the production of high content plant extracts and pharmaceutical intermediates all the year round
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Product Introduction

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of platycodon grandiflorus root extract in China. Please feel free to wholesale high quality platycodon grandiflorus root extract for sale here from our factory. For price consultation, contact us.

 

Product description

 

Platycodon Grandiflorus Root Extract is a natural medicinal ingredient extracted from Platycodon grandiflorus plant. Platycodon grandiflorum is a common herbal medicine widely used in China, Korea and Japan.

 

Bellflower extract mainly contains a variety of active ingredients, the most important of which is Platycodin saponins, a class of saponins with medicinal value. Platycodon saponins have anti-inflammatory, antibacterial, cough-relieving and phlegm-reducing pharmacological effects, and are widely used in the treatment of respiratory diseases such as cough, bronchitis, cold and tracheitis.

 

In addition, the bellflower extract also contains a variety of other components, such as bellflower polysaccharides, bellflower acid, bellflower acid, etc., which have certain biological activities and pharmacological effects.

 

Platycodon-Grandiflorus-Extract-Powder

 

Why choose KINTAI?

● We can do third-party testing.
● We guarantee the quality is in accordance with the certificate of analysis we provide, otherwise we accept 100% exchanges, returns and refunds.
● Any consulting questions and complaints, we can reply you within one hour.
● Independent factory production: We can strictly control the production process to ensure the quality and safety of products, and at the same time provide cheap prices.
● Sufficient inventory supply: We can process orders in a timely manner and ensure a stable supply of products required by customers.

 

Products Description

 

 Photograph of Platycodon Grandiflorus Extract process

 

 

 Product Quality Standard 

 

Product name

Platycodon Grandiflorus Root Extract

Extraction Solvent

Ethyl alcohol

Solubility

Insoluble in water, easily soluble in methanol, ethanol and other organic solvents and dilute alkali, showing weak acidity.

Identification

TLC , HPLC

Sulphated Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay 

Min. 95.0%

Residual Solvents

 

- N-hexane

NMT 290 PPM

- Methanol

NMT 3000 PPM

- Acetone

NMT 5000 PPM

- Ethyl Acetate

NMT 5000 PPM

- Ethanol

NMT 5000 PPM

Pesticide Residues

 

- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT)

NMT 0.05 PPM

- Aldrin, Endrin, Dieldrin

NMT 0.01 PPM

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 10³

- Moulds and yeasts, CFU/g, not more than

NMT 10²

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine.

Shelf life

2 years

 

Function

 

1. Anti-inflammatory and antioxidant effects:

The flavonoids in Platycodon Grandiflorus Root Extract have antioxidant activity, can neutralize free radicals, reduce oxidative damage to cells, and protect the skin from factors such as environmental pollution and ultraviolet radiation.
Saponins have anti-inflammatory effects, can inhibit the release of inflammatory mediators, reduce inflammation, and help relieve sensitivity and redness.

 

Anti-inflammatory effects of saponins derived from the roots of Platycodon  grandiflorus in lipopolysaccharide‑stimulated BV2 microglial cells


2. Improves skin health:

Platycodon grandiflorum extract has a good moisturizing effect, can increase the moisture content of the stratum corneum, enhance the water retention capacity of the skin, and make the skin softer and smoother.
Bellflower extract also has calming and soothing properties that relieve skin irritation and discomfort and have a positive effect on the repair of sensitive and damaged skin.


3. Inhibit the growth of bacteria and fungi:

Platycodon grandiflora extract has certain inhibitory effects on a variety of bacteria and fungi, which can block their growth and reproduction, thereby reducing related infection and inflammation problems.
Its antimicrobial activity makes it an ideal ingredient in products such as oral care products, skin antiseptic products and antiseptics.

 

4. Improve respiratory health:

Bellflower extract is widely used in traditional Chinese medicine to improve respiratory health. It can promote the relaxation of bronchial smooth muscle, relieve cough, reduce the viscosity of sputum, and help smooth breathing.

 

Improve Respiratory Health of Platycodon Grandiflorus Extract Powder

 

5. Immunomodulatory effect:

The polysaccharides in Platycodon grandiflorum extract have immunoregulatory effects, can stimulate the response of the immune system, enhance the body's immunity, promote the activation and proliferation of immune cells, and improve the body's resistance to pathogenic microorganisms.

 

References:
Kim JH, et al. (2015). Platycodin D, a triterpenoid saponin from Platycodon grandiflorum, inhibits LPS-induced iNOS, COX-2, and TNF-α expression through suppression of NF-κB activation in RAW 264.7 cells.
Jang S, et al. (2016). Platycodin D isolated from Platycodon grandiflorum enhances the immunogenicity of Newcastle disease vaccine.
Shim EY, et al. (2011). Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT activation.
Lee HH, et al. (2011). Decursin and decursinol from Angelica gigas Nakai enhance the immunological function of bone marrow cells and splenocytes.
Kim SH, et al. (2014). Platycodin D induces G2/M cell cycle arrest and apoptosis in hormone refractory human prostate cancer cells by targeting Akt signaling pathway.

 

Application

 

1. Pharmaceutical preparations:

  • Bronchitis and cough medicine: Platycodon Grandiflorus extract can be used to prepare medicines for acute and chronic bronchitis, cough and asthma, and other respiratory diseases. It can be used as a raw material for oral preparations, injections or local sprays, and has the effects of eliminating phlegm, relieving asthma, and reducing phlegm.
  • Oral care medicine: Platycodon Grandiflorus extract is also used in the treatment of oral diseases such as oral ulcers and gingivitis. It can be used as an ingredient in gargles, mouth sprays, or oral gels and has anti-inflammatory, antibacterial, and analgesic properties.

 

2. Cosmetic:

  • Skin care products: Platycodon Grandiflorus extract is rich in various antioxidant components, suitable for whitening, anti-aging and anti-wrinkle products in skin care products. Its moisturizing, soothing, astringent, and purifying properties improve skin texture, elasticity and radiance.
  • Sunscreen: The antioxidant substances in bellflower extract can help block the damage of ultraviolet rays to the skin, and can be used in sunscreen products, which have the properties of antioxidant, moisturizing, and repairing.

 

3. Health products:

  • Respiratory tract health: Platycodon Grandiflorus extract can be used as a component of health products to regulate respiratory system function, enhance immunity, prevent and relieve respiratory tract infection, bronchitis and other diseases.
  • Immune regulation: Platycodon Grandiflorus extract can be used to prepare immune regulation health products, promote the balance and strengthening of the body's immune function, improve the body's resistance, and prevent infection and disease.

 

Shipping & Storage

 

 

Packing and shipping

 

 

The production process of Platycodon Root Extract

 

KINTAIS PROCESSING

 

About Kintai

 

1)Kintai manufacturing base

 

Kintai manufacturing base

 

2Kintai R&D center

 

Kintai R&D center

 

3)Kintai factory

Kintai-Factory

 


Platycodon Grandiflorus Root Extract is one of our main products, we have enough stock, if you are interested, welcome to contact us by email,E-mail:cheney@kintaibio.com

 
 

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