Apple Root Extract Powder Phloridzin

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of apple root extract powder phloridzin in China. Please feel free to wholesale high quality apple root extract powder phloridzin for sale here from our factory. For price consultation, contact us.

Phlorizin is a unique dihydrochalcone compound in apple trees. It can regulate blood sugar, resist oxidation, whiten and fight acne, enhance cognition, etc. As a leading company in the field of plant extraction for 15 years, we rely on our 10,000-acre organic apple planting base and 10,000-ton extraction production line to launch 98% and 90% high-purity phlorizin, providing standardized and cost-effective raw material solutions for global customers.

Natural source and scientific extraction

• Plant source: Our raw materials are collected from the organic apple planting base in Yantai, Shandong, China (GAP certified). The content of phloridzin in apple tree root bark is as high as 3%-5%, far exceeding that of ordinary varieties.
• Extraction process: We use ultrasonic assisted extraction + membrane separation and purification technology to avoid high temperature damage to active ingredients, increase extraction efficiency by 40%, and stabilize the purity at 90%-98% (HPLC detection), without solvent residue, in line with ISO 22000 and FDA-GRAS standards.

Core ingredients and physical and chemical properties

• Chemical name: Phloridzin
• 

• CAS Number	60-81-1	Molecular Weight	436.409
  Density	1.6±0.1 g/cm3	Boiling Point	770.0±60.0 °C at 760 mmHg
  Molecular Formula	C21H24O10	Melting Point	113-114 °C(lit.)
  Common Name	Phlorizin	Flash Point	270.7±26.4 °C

• Appearance: Brown to white fine powder (color gradient varies slightly due to different purity)
• Particle size: 80 mesh sieve pass rate ≥95%, excellent solubility and dispersibility
• Stability: It can be stored for a long time under sealed light-proof conditions, and is not easy to agglomerate when stored at room temperature

1. Medicine and health products: natural sugar control, reshaping metabolic health

• Diabetes management:

Pherorisin double blocks glucose absorption by inhibiting renal SGLT2 and intestinal SGLT1 transporters. Clinical data show that it can reduce postprandial blood sugar peak by 30% without the risk of hypoglycemia.

• Heart and brain health:

Reduce serum triglycerides (by 25%) and LDL levels, and improve memory function through the blood-brain barrier (spatial memory ability increased by 40% in mouse experiments).

2. Beauty and skin care: whitening and anti-acne, the new favorite of ingredient party
Oil control and anti-acne: inhibit epidermal cell glucose uptake and reduce sebum secretion (in vitro experiments show that sebaceous gland activity is reduced by 50%), suitable for acne essence and cleansing products.

Whitening and spot removal: tyrosinase inhibition rate exceeds 60% (equivalent to arbutin), and it has stronger light stability, suitable for daytime whitening products.

3. Functional food: Double breakthrough in anti-oxidation and sugar control

• Natural preservation: The antibacterial effect of phloridzin, a degradation product of phloridzin, is comparable to that of sodium benzoate, and can be used in baking and beverages to extend the shelf life.
• Low GI food: Adding 0.1% phloridzin can reduce the glycemic index (GI) of food by 20%, which is suitable for meal replacement powder, sugar-free chocolate, etc.

4. Innovation field: Animal health and plant pesticides

• Pet health: Adding phloridzin to pet food improves the insulin sensitivity of obese dogs, and the European and American markets report that the repurchase rate has increased by 35%.
• Green agriculture: Phloridzin has an inhibition rate of over 90% on fruit and vegetable pathogens, and can be used to develop biological pesticides to replace chemical preparations.

1. Full-link quality control system
Raw material testing: 316 pesticide residues and heavy metal screening (in compliance with EU 396/2005 standards).

Production standards: 100,000-level clean workshop, FSSC 22000, HALAL, KOSHER certified.

Batch report: HPLC-MS test spectrum is provided for each batch, and SGS and Eurofins third-party re-inspection are supported.

2. Flexible supply and rapid response
Sufficient inventory: 50 tons of spot are always available, and emergency orders can be shipped within 72 hours.

Customized service: Can provide phlorizin microcapsules (sustained release technology), nanoliposomes (transdermal absorption rate increased by 3 times) and other dosage forms.

3. Value-added service
Formula support: Free application formula white papers in the fields of medicine, cosmetics, and food.

Compliance consulting: Assist in completing regulatory declarations such as FDA, EFSA, and NMPA.

(1) Raw material pulverization: the dried apple branches or leaves are pulverized into 10-20 mesh or 20-30 mesh coarse powder;

(2) Extraction: Put the pulverized coarse powder raw materials into a round bottom flask, add 70% methanol to reflux, and extract 3 times, each time adding the liquid volume of 6, 4, 4BV, each time 1h, combine the extracts; (three extracts tan to brown respectively)

(3) Concentration: add the antioxidant VC to the combined extract by 0.2% of the total weight of the extract, distill under reduced pressure at 60°C, and recover methanol; (the concentrated solution is a brown turbid liquid) Add poly alumina to the alcohol-free concentrated solution by 0.5% by weight, adjust the pH value to 7.5 with calcium hydroxide, put it in a conical flask, keep it warm at 60°C for 30 minutes, and filter it to obtain the clear liquid; (after adding polyalumina, the bottle flocculent sediment at the bottom)

(5) Extraction: Cool the extract concentrate, extract 3 times with 1 times the amount of ethyl acetate to obtain ethyl acetate solution; (solution layered rapidly)

(6) Concentration: the ethyl acetate extract was refluxed under reduced pressure and concentrated to 10:1 to obtain a concentrated solution;

(7) Purification: Dissolve the concentrated solution in 40% methanol, filter with suction, leave the filtrate for 24 hours, and filter with suction to obtain crystals, phlorizin dried under normal pressure or reduced pressure. (Yellow powder) Decolorize the crude product with activated carbon. The reason why activated carbon is selected is that its decolorization principle is physical adsorption, which will not cause harm to the biological activity of phlorizin. Dry the activated carbon in a vacuum oven. Make it activated; then add the activated carbon into the crude product aqueous solution, stir, and filter to obtain a clear liquid. Place natural crystallization, and finally, white needle-like crystallization appears.

For any other Questions, please feel free to contact us at cheney@kintaibio.com or feedback on the next page.

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