Name: Astragalus Membranaceus Extract
Brand: Kintaibio
SKU: 191756751

1. Introduction of Astragalus Extract

Astragalus membranaceus extract is the dried root extract of the leguminous plant Astragalus membranaceus

Astragalus polysaccharide is one of the main active components of Astragalus, which is obtained by high-tech extraction and separation.

It can be used as an immune enhancer or regulator. Astragalus has the functions of benefiting qi and solidifying the surface, astringing sweat and solidifying shedding, supporting sores and promoting muscle growth, and diuresis and swelling. For the treatment of qi deficiency and fatigue, depression of the middle qi, prolonged diarrhea and prolapse of the rectum, metrorrhagia, and metrorrhagia, spontaneous perspiration, carbuncle difficult to collapse, prolonged collapse, chlorosis due to blood deficiency, internal heat, and quenching thirst, chronic nephritis, proteinuria, diabetes, etc.

astragalus membranaceus extract

Product name	Astragalus Root Extract
Extract source	Dried root of Astragalus mongholicus
Extraction Solvent	Water/Ethyl alcohol
Appearance	Brown-yellow or gray-white powder
Solubility	-
Identification	TLC, HPLC
Ash	NMT 0.5%
Heavy metals	NMT 20 PPM
Loss On Drying	NMT 5.0%
Powder size	80Mesh, NLT90%
Assay	Min. 98.0%
Microbiological Quality (Total viable aerobic count)
- Bacteria, CFU/g, not more than	NMT 10³
- Moulds and yeasts, CFU/g, not more than	NMT 10²
- E.coli, Salmonella, S. aureus, CFU/g	Absence
Shelf life	This product should be sealed and shaded, avoid high temperatures, stored in a dry, cool, well-ventilated place, can be stored for 2 years

1.1 【Product Properties】

This product is a brown-yellow or off-white powder.

1.2 【Pharmacological action】

Increase immunity, increase energy, resist fatigue, resist mutations, protect the liver, and suppress osteoclasts. Ragweed polysaccharide has the effect of lowering the blood lipids, that is, lowering cholesterol and triglyceride, and increasing the high-density lipoprotein. It is used for the prevention and treatment of cardiovascular disease and cerebrovascular diseases such as atherosclerosis, coronary artery disease, peripheral vascular disease, and hyperlipidemia. Astragaloside IV has the effect of drastically lowering the blood sugar level, glycosylation hemoglobin, and urinary protein, and can reduce the AGS in the kidney cortex and serum. It shows that astragaloside IV has the effect of antioxidants, inhibition of aldose reductase, inhibition of mesangial cell proliferation, and a decrease in renal hypertrophy. Adding appropriate excipients to the astragaloside can be an oral preparation used to prevent and treat diabetic nephropathy.

2. Introduction of plant extract source

The Astragalus is also known as the Myanmar. In addition to the fruit of range and range, range, range leaf, eggplant dragonfly, range afflatus, and range Berge are also used for medicine.
Perennial grass of 50 to 80 cm. The main root is deep, long, rod-shaped, slightly woody. The dry root is cylindrical and small. It is thick and thin. Both ends are flat and are 20 to 70 cm long and 1 to 3 cm thick. The surface is yellow or light brown. They all have irregular vertical folds or grooves. The air is weak and special. It bites and the smell of the beans. The flowering period is from June to July and the fruiting period is from August to September. Excavation in autumn.
Born in the valley of the jungle, distributed in Hebei Province, Shanxi Province, Shaanxi Province, Sichuan Province, Gansu Province, etc.

Astragalus

3. Chemical & Physical Properties

Astragaloside IV（Astragaloside A）：

CAS Number	83207-58-3
Density	1.4±0.1 g/cm3
Boiling Point	895.7±65.0 °C at 760 mmHg
Melting Point	284-286ºC
Molecular Formula	C41H68O14
Molecular Weight	784.970
Flash Point	495.5±34.3 °C
Exact Mass	784.460938
PSA	228.22000
LogP	1.96
Vapor Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.621

Astragaloside IV

Astragalus polysaccharide:

CAS Number	89250-26-0
Density	1.4±0.1 g/cm3
Boiling Point	406.2±30.0 °C at 760 mmHg
Melting Point	154.5ºC
Molecular Formula	C10H7ClN2O2S
Molecular Weight	254.693
Flash Point	199.5±24.6 °C
Exact Mass	253.991669
PSA	86.95000
LogP	2.71
Vapor Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.638

Astragalus polysaccharide

4. Benefits and Application Of Astragalus membranaceus extract

The main active ingredients of Astragalus Root Extract, Wild Ginger Extract, which have many unique effects as below:

(1) Astragalus has the effects of enhancing the body's immune function, strengthening the heart and lowering blood pressure, lowering blood sugar, diuresis, anti-aging, and anti-fatigue.

Benefits of astragalus membraneceus extract

(2) Astragalus polysaccharide has the effect of lowering blood lipids, that is, lowering cholesterol and triglycerides, and increasing high-density lipoprotein; it can prevent and treat cardiovascular and cerebrovascular diseases, such as atherosclerosis, coronary artery disease, peripheral vascular disease and high blood pressure. Lipidemia, etc.

(3) Astragaloside IV has the effect of significantly reducing blood sugar, glycosylated hemoglobin and urinary protein, and can reduce AGEs in renal cortex and serum, showing that astragaloside IV has antioxidant effect and inhibits aldose reductase. Inhibit the proliferation of mesangial cells and reduce renal hypertrophy.

Astragalus-polysaccharide-has-hypolipidemic-effect

(4) Adding appropriate excipients to astragaloside IV can be made into oral preparations, which are used to prevent and treat diabetic nephropathy.

Adding appropriate excipients to make stilbinoside into oral preparations is used to prevent and treat diabetic nephropathy

Application

Astragalus Root Extract is widely used in medicine, health products, veterinary medicine and other fields.

5. Extraction Method

Take slices of Astragalus membranaceus, decoct twice with water, combine the extracts, concentrate under reduced pressure, add ethanol to the concentrate to make the alcohol content reach 60%, filter the precipitate, dissolve it with water, remove insoluble matter by centrifugation, concentrate the filtrate under reduced pressure to an appropriate amount, Add ethanol to make the alcohol content reach 80%, let it stand at room temperature overnight, pour out the supernatant, add ethanol to the precipitated part, stir, filter, wash with ethanol, and dry in vacuo. This process is suitable for the production of astragalus extract (70%), and the yield is about 2.5%.

Extraction process