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1. Introduction of Cornus officinalis extract
Cherry Fruit Extract is a yellow or brownish-yellow powder, extracted from the mature pulp of Nakai, Macrocarpium off-single (Sieb. etZucc.). It can nourish the liver and kidney, astringent the essence, and remove the essence. It can inhibit pathogenic bacteria. Injection can strengthen the heart, boost blood pressure, inhibit platelet aggregation, and prevent thrombosis. It has an anti-experimental liver damage effect. For leukopenia caused by chemotherapy and radiotherapy, it has the effect of raising it. It also has an antioxidant effect. It has a weak excitatory parasympathetic effect. The mixture contained has a convergence effect.
The extract of Cornus officinalis is an astringent drug, which is extracted from mature fruit pulp.
The drug combination of Cornus officinalis extract showed obvious effects on the expression of nerve growth-related proteins around the wound, the growth of axons, the reduction of free radical damage in the brain, the overload of calcium ions in neurons, the enhancement of the binding force of M-cholinergic receptors, the enhancement of choline acetyltransferase activity, the inhibition of acetylcholinesterase and monoamine oxidase B activities in various nerve injury animal models; It can reduce the loss of neurons, improve the learning and memory function, and have a good protective effect on various kinds of damage to neurons.

|
Product name |
Cornus officinalis extract |
|
Extract source |
Fruits of Cornus officinalis |
|
Extraction Solvent |
Water/Ethyl alcohol |
|
Appearance |
Brown yellow powder |
|
Solubility |
Soluble in water |
|
Identification |
TLC , HPLC |
|
Sulphated Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of Cornus officinalis extract (HPLC test, percent, Standard in House) |
Min. 98.0% |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Shelf life |
This product should be sealed and shading, avoid high temperature, store in a dry, cool, well-ventilated place, can be stored for 2 years |
1.1.Introduction of plant extract source
Cornus officinalis is also known as Shu jujube, medicinal jujube, jujube peel and cornus flesh. It is the mature pulp of Macrocarpium officinale (Sieb. etZucc.) Nakai, a plant of Cornaceae.
Distribution: Shanxi, Shaanxi, Gansu, Shandong, Jiangsu, Zhejiang, Anhui, Jiangxi, Henan, Hunan and other provinces in China. It is also distributed in North Korea and Japan. Born in the forest edge or forest with an altitude of 400-1500 meters and a sparse height of 2100 meters. It is introduced and cultivated in Sichuan.
The fruit of this species (including the Fructus Corni of Sichuan and Hubei) is called "cornus flesh", commonly known as jujube peel. It is used for medicine. It is sour in taste and mild in nature. It is a astringent and strong medicine with the effect of tonifying the liver and kidney and stopping perspiration.

1.2 Active ingredients
Contains Morningside, 7-0-methylmorroniside, seaside, login, dogwood tannin 1, 2, 3. (Cornus-tannin1,2,3) etc. Extraction and Separation.
2. Benefits and Application
2.1 The main active ingredient of Cherry Fruit Extract, Wild Ginger Extract, which has many unique effects as below:
(1)Hypoglycemic.
(2)Antineoplastic.
(3) Anti-inflammation and bacteriostasis.
(4)The extract of Cornus officinalis also has the effects of promoting immune response, anti-arrhythmia, anti-oxidation, anti-aging, liver protection, etc.

2.2 Application
Cornus officinalis extract is widely used in the medical field.
3. Extraction and Separation
1). Song Chunjing et al. took the content of Morningside as an index and used a single factor test and orthogonal test to optimize the extraction process. The sample volume, elution speed, eluent concentration, and dosage were selected as the investigation factors, and the purification process of HPD-300 macroporous adsorption resin was investigated by a single-factor experiment. Results: The best extraction process of Cornus officinalis was to add 8 times the amount of 50% ethanol to extract three times, each time for 3 hours. The purification process is 3 BV 30% ethanol to 1. 5 BV. h-1 elution, elution rate of 94.9%. Conclusion: The optimal extraction process is stable and feasible; HPD-300 macroporous adsorption resin can purify the total glycosides of Cornus officinalis well.
2). In the process research of Zhizhi Granules, Wu Chuang took the content of ursolic acid as the evaluation index and used the orthogonal test method to optimize the extraction process of the main component, Cornus officinalis. The key factor of the process and the alcohol reflux extraction time have the least influence on the extraction process of Cornus officinalis.

4.The production process of Cherry Fruit Extract

5. Kintai's advantage

6.Kintai manufacturing base

7.Kintai R&D center

8.Package and Shipment

9.Safety information
Security Statement: (Europe) 24/25
NONH for all modes of transport
Customs code: 2929909090
10.KINTAI is committed to being your best Cherry Fruit Extract supplier
★For any other Questions, please feel free to contact us at cheney@kintaibio.com or feedback in next page.
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