Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of oxysophoridine powder in China. Please feel free to wholesale high quality oxysophoridine powder for sale here from our factory. For price consultation, contact us.
Bulk oxysophoridine powder manufacturer
The 98% pure Oxysophoridine (Oxysophoridine N-oxide) powder produced by Kintai is a highly active natural alkaloid extracted from bitter bean (scientific name: Sophora alopecuroides Linn). Due to its strong antioxidant, anti-inflammatory, anti-apoptotic and other multiple biological activities, it has gradually been widely used in medical fields such as antibacterial, antiviral and anti-infective, and has shown significant effects in the maintenance of cardiovascular and cerebrovascular health.
Product specifications:
assay: 98% Oxysophoridine , in line with European and American pharmacopoeia standards.
Packaging: 10kg/barrel, lined with double-layer sterile bags or 0.5-5kg/bag, aluminum platinum bag vacuum packaging.
Extraction Source: Sophora alopecuroides, after strict quality control, to ensure the stability and purity of each batch of products.
Our raw material powder has undergone strict scientific purification and quality control, with a purity of 98%. The active ingredients are tested by HPLC to ensure stability, safety and effectiveness. My current product has been widely used in the research and development of health products and cardiovascular and cerebrovascular disease prevention. Our product is suitable for drug preparation and advanced health care products.
Pharmacological effects of Oxysophoridine
1. Anti-inflammatory and anti-infective effects
Oxysophoridine has strong antibacterial and anti-inflammatory effects. Studies have shown that it can inhibit a variety of bacteria including Shigella, Sonnei, and Fusarium. Its antibacterial mechanism is mainly through regulating the activation of the NF-κB signaling pathway, thereby reducing the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2), and then significantly reducing the levels of inflammatory factors such as TNF-α, IL-6, and NO. It has a significant effect on the prevention and treatment of infectious diseases and can relieve the inflammatory response caused by bacteria and viruses.
2. Cardiovascular protection: Antioxidant and anti-apoptotic mechanism
Oxysophoridine has a good protective effect on cardiovascular and cerebrovascular diseases due to its excellent antioxidant properties. It can delay the progression of cardiovascular and cerebrovascular diseases by inhibiting oxidative stress and reducing the damage of free radicals to cells, especially in disease models such as acute myocardial ischemia, arrhythmia, chronic heart failure, and cerebral ischemia-reperfusion injury. Oxidized sophoridine effectively reduces oxidative damage and helps maintain cardiovascular and cerebrovascular health by reducing the content of malondialdehyde (MDA) in the cerebral ischemia model and increasing the levels of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px).
Oxysophoridine can also play a neuroprotective role by regulating the apoptosis pathway. It can increase the Bcl-2/Bax ratio, inhibit pro-apoptotic factors such as caspase-3 and caspase-8, reduce apoptosis, and thus protect the viability of nerve cells and cardiomyocytes. Experimental studies have shown that it has a significant inhibitory effect on apoptosis in animal models of acute myocardial ischemia and cerebral ischemia-reperfusion injury.
3. Myocardial protection: against acute myocardial ischemia and arrhythmia
Acute myocardial ischemia is a serious pathological state caused by a sudden decrease in blood supply to the heart. Oxidized sophoridine reduces the risk of myocardial infarction by enhancing myocardial contractility and reducing myocardial ischemic damage. In addition, Oxysophoridine significantly reduced the infarction range and reduced the necrosis rate of myocardial cells in the acute myocardial ischemia model. Compared with the control drug, the effect of oxidized sophoridine is more lasting and is expected to become one of the natural ingredients for myocardial protection.
In terms of the prevention and treatment of arrhythmias, oxidized sophoridine has shown the effect of stabilizing heart rate in studies, can reduce the occurrence of arrhythmias induced by aconitine and acetylcholine, has negative frequency and conduction effects, helps regulate abnormal heart rate, and improves heart tolerance.
4. Cardiovascular and cerebrovascular disease protection: an ideal choice for natural oxidized sophoridine
As modern people pay more and more attention to cardiovascular and cerebrovascular health, Xi'an Kintai's oxidized sophoridine products provide a new choice for health maintenance. Preclinical experiments have shown that oxidized sophoridine has shown excellent potential in protecting cardiovascular and cerebrovascular health through multiple biological mechanisms. It is not only suitable for the research and development of cardiovascular and cerebrovascular diseases, but also provides the market with natural plant ingredients with multiple functions.
Application areas and recommended dosages
98% oxidized sophoridine powder can be used in the field of cardiovascular and cerebrovascular health, anti-inflammatory and antibacterial formulations, and health products or functional food formulations that support nervous system health. The high-purity oxidized sophoridine powder provided by Kintai can be completely soluble in organic solvents such as methanol, ethanol and DMSO. It is easy to use and can be easily added to various pharmaceutical product formulations.
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In animal experiments, oxidized sophoridine has a high safety profile and shows minimal toxic side effects. However, further clinical trials are needed to support the dosage and safety assessment for human use. Therefore, it is recommended to follow the recommended dosage in drug development and to make corresponding scientific designs based on product needs.
Why choose 98% Oxysophoridine from xi'an kintai biotech inc?
We are committed to providing high-quality, high-purity natural plant ingredients to global customers with the most advanced extraction technology and scientific quality control standards. Our Oxysophoridine products are of high purity and stable quality. After multi-level testing and strict control, we provide customers with one-stop raw material supply services. Our Oxysophoridine powder is not only suitable for pharmaceutical development, but also suitable for development as an active ingredient for high-end health foods and drugs.
our certifications
What can KINTAI do for you?
If you want to know more about the product information of 98% Oxysophoridine powder or consult cooperation matters, please contact the professional team by Email: sales@kintaibio.com. We will provide you with detailed product information and full technical support.
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