Part1:What is Centella asiatica extract and its active ingredients?
Centella asiatica , a dried whole herb of Centella asiatica plant in the family Apiaceae, was originally published in the 《Shennong Materia Medica》, with the effect of clearing heat and dampness, detoxifying and reducing swelling, and clinically used to treat bruises, skin diseases, etc.The main active ingredients in Centella asiatica extract extract that can be used in cosmetics are asiatica acid, madecassic acid, asiaticoside and madecassoside. Madecassoside which is a triterpene saponin compound of Centella asiatica extract, accounts for about 30% of total asiatica glycosides, and is one of the active ingredients with the highest proportion.
Part2: What are the effects and functions of Centella asiatica extract?
(1)Antibacterial activity
Centella asiatica extract extract contains asiatica acid, madecassic acid, these active saponins will acidify the cytoplasm in plant cells, this antibacterial activity can protect the plant itself against mold and yeast invasion.Experiments have shown that Centella asiatica extract extract has a certain inhibitory effect on Pseudomonas aeruginosa, Staphylococcus aureus, Propionibacterium acnes.
(2)Anti-inflammatory activityCentella asiatica extract total glycosides have a pronounced anti-inflammatory effect, reducing the production of pre-inflammatory mediators (L-1, MMP-1), improving and repairing the skin's own barrier function, thereby preventing and correcting skin immune disorders.
(3)Healing wounds and scars
This effect of Centella asiatica extract is widely used in dermatological clinical treatment.Asiaticoside and madecassoside are the active ingredients of Centella asiatica extract herbal medicine in the treatment of burns and wounds, which can promote collagen synthesis and new angiogenesis in the body, stimulating granulation growth, etc, so it is conducive to wound healing.At the same time, asiaticoside has a proliferative effect on epidermal keratinocytes, vascular endothelial cells, and has an inhibitory effect on fibroblasts, so as to promote granulation tissue formation in the early stage of wound healing and inhibiting scars in the late stage .Finally, asiaticoside promotes KGF-2mRNA synthesis on vascular endothelial cells at a certain concentration, thereby exerting KGF-2 in promoting keratinocyte proliferation, differentiation, chemotaxis, promoting wound healing, and indirectly promoting granulation tissue production, forming a virtuous cycle of wound healing.
(4)Anti-aging
Studies have shown that asiaticoside, asiatitic acid and madecassic acid can promote the secretion of more type I collagen by human fibroblasts in vitro, which is the main component of collagen in the dermis layer of the skin.Other studies have shown that assoside can both promote the production of type I collagen and is the only component of all triterpenoids that can promote the synthesis of type III collagen, which is the main component of many organs and the extracellular matrix of the skin.What’s more, DNA arrangement tests have found that Centella asiatica extract extract also has the activation effect of fibroblast genes, which can enhance the vitality of the cells of the basal layer of the skin, maintaining the elasticity and firmness of the skin, smooth -ing the fine wrinkles of the face. Additionally,Studies have shown that the combination of 0.1% of assoside and 5% vitamin C can effectively improve skin aging.
(5)Antioxidant
Asiaticoside, asiatica acid and madeasiatic acid all have obvious antioxidant activity, and animal experiments have shown that asiaticoside can induce a significant increase in the level of local peroxidoxidase, glutathione, catalase, VitChing, VitE and other antioxidants in the early stage of wound healing, and reduce the level of lipid peroxide on the wound surface by 7 times.In addition, Centella asiaticoside is also a good inhibitor of apoptosis, which has a significant biological effect on tissue cells by reducing the concentration of oxygen radicals in tissue cells.
(6)Whitening
Asiaticoside can inhibit tyrosinase activity dose-dependently, and the inhibition rate of Centella asiatica extract on tyrosinase by 4 μg/ml is 4%. The effect of using Centella asiatica extract cream for pigmentation was significantly better than that of hydroquinone cream, and the incidence of adverse reactions was significantly lower than that of the latter, but the onset of action was slightly slower than that of the latter.
Part3: Why is the Centella asiatica extract so hot in beauty skin care market?
《Indian Medical Magazine》has published research reports on Centella asiatica extract extract, which mentioned that in Centella asiatica extract extract, it does not contain caffeine or other irritating ingredients, which can be applied to almost any skin type and skin condition. Moreover, Centella asiatica extract extract extraction through high -purity extraction technology is more obvious for the repair of the skin dermis. Technically overcome the disadvantages of cedarcin unstable and easy to work, it greatly improves the permeable skin efficiency of cedarcoside.
On account of people are affected by multiple factors such as air, environment, pressure, and irritating food in their daily lives, the incidence of skin sensitivity is gradually increasing.Furthermore,frequent makeup removal and skin care products also bring certain pressure on skin barriers. Therefore Centella asiatica extract extract are favored by consumers with their strong skin repair forces .
