Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of natural d mannose powder in China. Please feel free to wholesale high quality natural d mannose powder for sale here from our factory. For price consultation, contact us.
1.Products Description
natural d mannose powder that is a component of many polysaccharides, a sugar related to glucose, which, like glucose, can be produced naturally in the body and exists in some plants in the form of starch. It is less sweet than sucrose (about 0.6 of sucrose, and about the same sweetness as erythritol, which is currently on the market) and can be used as a sugar substitute for diabetics because it is also a monosaccharide and cannot be hydrolyzed into glucose. Several fruits and vegetables contain mannose, including cranberries, apples, oranges, peaches, cauliflower, string beans, etc. Mannose is also found in some nutritional supplements, available in capsule or powder form.


2. Product quality specification & standard
|
Product name |
natural d mannose powder |
|
Extraction Solvent |
Water/Ethyl alcohol |
|
Appearance |
white powder |
|
Solubility |
Water soluble |
|
Identification |
HPLC |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of 99%alpha-D-mannopyranose (HPLC test, percent, Standard in House) |
Min. 95.0% |
|
Residual Solvents |
|
|
- Ethanol |
NMT 5000 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China |
|
Shelf life |
3 years |
3.What can KINTAI do?


4. Distribution
Mannose is important in human metabolism and is widely distributed in body fluids and tissues, especially in the nerves, skin, testes, retina, liver and intestine, where it is directly used to synthesize glycoproteins. Mannose is used as an additive in food and beverages, and is also used in medicine as an aid in the treatment of patients with diabetes, obesity, constipation and high cholesterol.

5.Chemical & Physical Properties
| CAS Number | 3458-28-4 | Molecular Weight | 180.156 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 527.1±50.0 °C at 760 mmHg |
| Molecular Formula | C6H12O6 | Melting Point | 133-140ºC |
| Common Name | natural d mannose powder | Flash Point | 286.7±26.6 °C |

6.Preparation
natural d mannose powder can be prepared by hydrolysis of D-mannopyranose-rich glycans (ivory palm seeds, yeast mannose, etc.). It can also be synthesized from D-mannitol (a by-product of the kelp iodine industry) by oxidation with hydrogen peroxide in the presence of ferrous ions. It can also be prepared by differential isomerization of D-glucose, or by growing the carbon chain of D-arabinose, etc.
7. Benefits and application
Benefits
1. Prevention of recurrent urinary tract infections
This is one of the most widely studied uses of D-(+)-Mannose, including cystitis, urethritis and other urinary tract problems. A large number of studies have shown that D-(+)-Mannose can effectively relieve the symptoms of urinary tract infections (reduce the frequency, urgency and pain of urination, reduce white blood cells and the number of bacteria in the urine, etc.); Adherence to D-(+)-Mannose can effectively prolong the recurrence cycle of urinary tract infections.

2. Inhibit the growth of cancer cells
Mannose has a significant inhibitory effect on common cancer cells such as ovarian cancer, breast cancer, prostate cancer, colorectal cancer, and kidney cancer. If mannose is used in combination with chemotherapy, it can have a better anti-cancer effect.

3. Treatment of immune system diseases
D-mannopyranose can regulate regulatory T cells (Treg) to suppress autoimmune diseases. Mannose can induce the differentiation of human initial T cells to regulatory T cells (Treg), in which D-mannopyranose induces Treg cell production through fatty acid oxidation and increasing free radical levels.

4. Improving the balance of intestinal flora
Mannose is an excellent prebiotic that enhances host health by selectively stimulating the growth or activity of one or a few bacteria in the colon and exerting beneficial effects on the host. It can prevent harmful bacteria from forming a bacterial biofilm in the human intestine.

Application
Beta-D-mannopyranose is a hexose with applications in food, cosmetics, medicine, and feed. It is found in a variety of fruits and plants and is an important component involved in human metabolism, especially in the glycosylation of certain proteins. As a naturally occurring bioactive monosaccharide, Alpha-D-mannopyranose is a popular nutritional and health food supplement, especially for use in dietary supplements as a phytonutrient supplement related to human health.
a.Food field
As a naturally occurring bioactive monosaccharide, L-glucopyranose is a popular nutritional and health food supplement, especially for use in dietary supplements as a health-related glycoconutrient supplement for the human body. When excreted through the kidneys, bladder, and urethra, mannose envelops the cells of the passing tissues and the bacteria that attempt to adhere to them, preventing the bacteria from adhering to the cells of the bladder and urethra, and blocking the pathway for bacterial infection. Alpha-D-mannopyranose has been proven in clinical trials to be as effective as antibiotics for the prevention of recurrent urinary tract infections (UTIs), with significantly fewer side effects.
b.Chemical synthesis
alpha-D-mannopyranose can also be used in the field of synthesis, such as methyl-α-D-mannopyranoside, nitrobenzyl-α-D-mannopyranoside, alkyl-α-D-mannopyranoside, D-mannuronic acid-1,4-lactone, L-ribose, etc.
c.Pharmaceutical field
d.Cosmetic field
L-glucopyranose has excellent effects on skin conditioning, making the skin feel less tight or dry, softer and smoother after washing. Alpha-D-mannopyranose was listed in the list of cosmetic ingredients by Environment and Climate Change Canada in 1994.

8.Properties of D-mannopyranose
Physical properties of D-mannopyranose
D-(+)Mannose is easily soluble in water, slightly soluble in ethanol, and insoluble in ether. Its pure product is white crystal or powder, a sweet taste, and slightly bitter taste, melting point is 132C (a-type crystal form) ~133C (beta-type crystal form), two configurations of D-(+)Mannose a-type (methyl Crystallization) The specific rotations of β-type (ethyl crystal) in aqueous solution are [a]p20+29.3->+14.6*, [a]p20-293-→+14.6°%.
Chemical Properties of D-(+)Mannose
alpha-D-mannopyranose is a reducing monosaccharide with reducing properties. It can generate metal or metal subvalent oxide under the action of weak alkaline oxidant, and generate mono- or binary D-mannonic acid or this produces formic acid and methanol. alpha-D-mannopyranose can also react with alcohol or molecules with hydroxyl groups to form glycosides, and at the same time, multiple hydroxyl groups of alpha-D-mannopyranose itself can also undergo esterification reactions with acids. When alpha-D-mannopyranose interacts with three molecules of phenylhydrazine, alpha-D-mannopyranose is produced.Alpha-D-mannopyranose has a characteristic crystal shape and a certain melting point, and the properties of sugar can be used to identify Alpha-D-mannopyranose. When the reducing agent acts on alpha-D-mannopyranose, alpha-D-mannopyranose is reduced to D-mannitol. D-mannitol is a hypertonic tissue dehydrating agent, which has been widely used clinically.
9. KINTAI'S PROCESSING

10.Why choose Kintai?

11. Kintai manufacturing base

12.Kintai R&D center

13.Package

TIPS
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