Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of polydatin powder in China. Please feel free to wholesale high quality polydatin powder for sale here from our factory. For price consultation, contact us.
98% Polydatin Powder Supplier/Manufacturer
KINTAIBIO®'s Polydatin powder is a natural active ingredient derived from the dried rhizome of Polygonum cuspidatum. Physically, it is a white, needle-like crystalline powder, readily soluble in organic solvents such as methanol and ethanol. We routinely supply 98% high-purity Polydatin powder, analyzed by HPLC to ensure consistent quality and controllable impurities in each batch, meeting high quality standards.
Based on solid scientific evidence, our polygonum cuspidatum root extract powder has broad application prospects. In the pharmaceutical field, it is a high-quality raw material for the research and development of drugs for cardiovascular diseases, metabolic diseases, neurodegenerative diseases, and anti-tumor diseases. In the health food field, it can be used to develop products with liver-protective, lipid-regulating, and antioxidant functions. In the cosmetics field, due to its excellent antioxidant and anti-radiation capabilities, it can be used as a core ingredient in functional skincare products.
We are committed to providing you with high-purity, high-quality, and highly stable polydatin powder to support your product development and marketing. You can contact us at sales@kintaibio.com.
COA Of Polydatin Powder
Specification Of Polydatin Powder
| Assay | 20%,50%,98% Polydatin by HPLC |
| Appearance | White Powder |
| Loss on Drying | < 5 ppm |
| Heavy Metals | < 10ppm |
| Total Plate Count | < 10,00cfu/g |
| Yeast & Mold | < 1,000cfu/g |
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You May Also Like Other Polygonum Cuspidatum Extract Powder
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Polydatin
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More detailes about our polydatin
polydatin vS resveratrol
Higher stability and bioavailability: Resveratrol has an oral bioavailability of less than 1% due to its easy oxidation and low water solubility. However, polydatin has significantly improved its water solubility and metabolic stability through the glucose modification at the C3 position, and its bioavailability can reach more than 5 times that of resveratrol (Pharmacological Research, 2018).
Enhanced antioxidant capacity: The antioxidant activity of polydatin antioxidant polydatin (measured by ORAC value) is 20%-30% higher than that of resveratrol, which can more efficiently scavenge free radicals and delay cell oxidative damage (Journal of Agricultural and Food Chemistry, 2016).
Targeted anti-tumor potential: Many studies have shown that polydatin inhibits cancer cell proliferation and induces apoptosis by regulating the PI3K/AKT and NF-κB pathways. Its anti-cancer activity is particularly prominent in colon cancer and breast cancer models (Cancer Letters, 2020).
polydatin Diversified benefits verified by the market
Cardiovascular health: regulating blood lipids (lowering LDL-C, increasing HDL-C), inhibiting platelet aggregation, and reducing the risk of atherosclerosis (Atherosclerosis, 2019).
Anti-inflammatory and immune regulation: inhibiting the expression of COX-2 and TNF-α, effectively relieving chronic inflammation (such as arthritis, intestinal inflammation) (International Immunopharmacology, 2021).
Metabolic support: improving insulin sensitivity and reducing the risk of diabetic complications (Diabetes Research and Clinical Practice, 2017).
Skin protection: enhancing skin barrier function and reducing UV damage by activating the Nrf2 pathway (Journal of Cosmetic Dermatology, 2022).
How to make Polydatin Powder ?
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Polydatin powder benefits
Polydatin Powder in skincare
Recent research confirms the significant efficacy of polydatin powder in protecting skin from photoaging. UVA radiation penetrates deep into the dermis, inducing mitochondrial dysfunction and oxidative stress, which are major factors contributing to photoaging. Polydatin effectively combats this damage through multiple mechanisms: it not only significantly reduces UVA-induced intracellular reactive oxygen species levels, protecting cell vitality, but also maintains mitochondrial integrity at a core level-ensuring cellular energy supply by protecting mitochondrial membrane potential and improving respiratory function, while simultaneously regulating mitochondrial homeostasis, inhibiting excessive mitochondrial division, and promoting fusion.
Source:https://www.mdpi.com/
Furthermore, polydatin activates the intracellular Nrf2 antioxidant pathway, increases reduced glutathione levels, and enhances the skin's own defense capabilities. These findings demonstrate the important role of polydatin powder in functional skincare products that combat photoaging and oxidative skin damage.
Polydatin Powder cancer
Related research has revealed the immense potential of polydatin powder as a natural multi-target anticancer compound. Studies have confirmed that polydatin glycoside exhibits significant inhibitory activity against various malignant tumors, including colorectal cancer, breast cancer, lung cancer, liver cancer, osteosarcoma, cervical cancer, and ovarian cancer. Its mechanism of action covers multiple key stages of cancer development: it effectively inhibits cancer cell proliferation, induces apoptosis, and weakens the migration and invasion capabilities of cancer cells by reversing the epithelial-mesenchymal transition process.
Source:https://www.sciencedirect.com/
Polydatin glycoside can also regulate inflammatory factors in the tumor microenvironment and interfere with key pro-cancer signaling pathways such as PI3K/AKT and JAK/STAT3. Of particular note, polydatin glycoside can enhance the sensitivity to chemotherapeutic drugs such as 5-fluorouracil and paclitaxel, and reduce the cardiotoxicity of certain drugs, demonstrating excellent synergistic and detoxification potential. These research findings provide a solid scientific basis for polydatin powder as a functional raw material for adjuvant cancer therapy and recurrence prevention.
Reference:https://www.mdpi.com/2073-4409/14/21/1702
https://www.sciencedirect.com/science/article/pii/S2225411024000713
Polydatin Powder uses
Polydatin Powder Supplements
In the health supplement industry, polydatin powder can be developed as a core active ingredient into polydatin supplements. For example, it can be formulated into easily swallowed polydatin capsules, softgels, or compressed tablets, targeting middle-aged and elderly individuals or those with cardiovascular sub-health. Through scientific formulation at the recommended daily intake, long-term use can help regulate lipid metabolism, protect vascular endothelial function, and achieve daily cardiovascular health maintenance.
Simultaneously, based on its proven hepatoprotective activity, polydatin can also be used in liver-protecting solid beverages and meal replacement powders. It provides more comprehensive liver support than traditional single detoxification ingredients, addressing the metabolic burden on the liver caused by modern lifestyles such as staying up late and drinking alcohol.
Polydatin Powder in Skincare product
In the cosmetics and skincare industry, polydatin powder effectively scavenges free radicals, inhibits skin collagenase activity, and reduces collagen loss, thereby slowing down the skin aging process. It is suitable for addition to anti-aging serums and firming creams to improve fine lines and sagging. Especially due to its gentle effects, it is suitable for use in anti-aging products for sensitive skin.
On the other hand, it has an inhibitory effect on skin inflammatory factors and can be used in products such as sensitive skin repair masks and acne gels to help relieve skin inflammation reactions such as acne redness and swelling and sunburn. At the same time, it helps to enhance the skin barrier function and improve the skin's ability to resist damage from the external environment.
where to buy Polydatin Powder?
As a professional polydatin powder supplier in China, we are committed to providing a stable supply of wholesale polydatin powder to our global partners through innovative technology and reliable quality. We routinely offer 98% high-purity polydatin powder, with each batch undergoing rigorous HPLC testing to ensure stable content and controllable impurities. Our entire production process adheres to international GMP standards, from raw material traceability to finished product packaging, with each step monitored by advanced testing laboratories, providing a solid raw material foundation for your product development and marketing.
Regarding the polydatin powder price, we adhere to the principle of combining high quality with reasonable costs. Leveraging our complete plant extraction production line and strong R&D support, we can not only offer highly competitive prices but also provide technical information and formulation development assistance to meet customized needs from pilot-scale to large-scale production. If you require samples, customized solutions, or wish to discuss cooperation, please contact us at sales@kintaibio.com.
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