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What Is Cissus Quadrangularis Extract Capsules?
Cissus quadrangularis extract capsules are dietary supplements that contain an extract derived from the Cissus quadrangularis plant. Cissus quadrangularis is a succulent vine native to certain parts of Asia and Africa. The extract is typically obtained from the stem of the plant and is known for its potential health benefits.
Cissus capsules are rich in various compounds, including vitamins, minerals, and phytochemicals such as flavonoids and triterpenes. It is believed to have anti-inflammatory properties and may help support bone and joint health. Some studies suggest that Cissus quadrangularis extract may aid in reducing joint pain, promoting bone healing, and improving overall joint mobility. These extract capsules are often used by individuals seeking natural remedies for joint-related issues, such as arthritis or sports injuries.

Products information
| Product Name | Cissus Quadrangularis capsule |
| Appearance | Brown capsules |
| Material | Cissus quadrangularis plant |
| Ingredients | 10:1 |
| Special Ingredients | Non-GMO, Vegan |
| Part Used | square-stem |
| Origin of Capsule | Veg capsule |
| Capsules Size | This product is 0#,we also provide 2#, 1#, 00# or as your request. |
| Capsules Content | This product is 500mg, we also provide 250mg, 300mg, 500mg, 700mg or as your request. |
| Package | This product is 60caps/bottle, we also provide 40caps/bottle, 55caps/bottle, 60caps/bottle, 120caps/bottle. |
| Bottle Size | This product bottle size is 120cc, we also provide 100cc, 110cc, 175cc. |
| Shipping Details | DHL /FEDEX/EMS/by sea or by air |
| Delivery Detail | Immediately |
| Nutrient Content | Vegan, Gluten-Free, Non-GMO, Natural |
| Certification | GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL |
| Place of Origin | Shaanxi, China(Mainland) |
| Contact | sales@kintaibio.com |
| OEM Service | OEM bag/bottle is available with private label. |

OEM & ODM Service
| Cooperate | OEM | Bags: Packed by 60g/bag,100g/bag, 100g/bag,500g/bag,1kg/bag, 25kg/drum according to your need. |
|
Capsule/soft gel: 40caps/bottle, 55caps/bottle, 60caps/bottle, 120caps/bottle Origin of Capsule:Vegan capsule, Gelatin capsule, or HPMC capsule |
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| Customized bag or capsule/soft gel formulations with private labeling. | ||
| Brand Name | Your brand | |
| Packaging Options | In bulk, bottle, blister or box | |
| Shipment Ways | DHL, FedEx, UPS, EMS, TNT, by Sea, By air | |
| Delivery Time | Prepare Product: About 5-7 days | |
| Shipping time | About 5~15 days | |
| Samples | Free samples | |
| Certification | GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL | |
| Supplier | Company Name | KINTAI BIOTECH INC. |
| Contact | sales@kintaibio.com | |
| Storage | Store in cool and dry places, keep away from strong light. | |
| Shelf Life | 2 years when properly stored. |

What do Cissus capsules do?
Joint Health:
Cissus quadrangularis capsules, derived from a perennial plant native to Africa and Asia, has gained attention for its potential to support joint health. The mechanism underlying its efficacy lies in its anti-inflammatory properties. Studies have shown that Cissus quadrangularis may inhibit the activity of pro-inflammatory enzymes, such as cyclooxygenase (COX) and lipoxygenase (LOX), which are involved in the production of inflammatory mediators like prostaglandins and leukotrienes (Oben et al., 2006). Modulating these pathways can help reduce inflammation and alleviate joint pain associated with conditions like osteoarthritis and rheumatoid arthritis.
Bone Healing:
The extract of Cissus quadrangularis has been investigated for its potential to promote bone healing and support bone health. Research suggests that Cissus quadrangularis may exert beneficial effects on osteoblasts, the cells responsible for bone formation. It has been reported to enhance osteoblast proliferation, differentiation, and mineralization, thereby contributing to the regeneration and repair of bone tissue (Potu et al., 2009). These findings indicate that cissus capsules could be beneficial for individuals recovering from fractures or those at risk of osteoporosis.
Weight Management:
In the context of weight management, Cissus quadrangularis extract has been studied for its multifaceted effects. It is proposed to impact weight regulation through several mechanisms, including appetite suppression, inhibition of adipocyte (fat cell) differentiation, and modulation of lipid metabolism. Additionally, research suggests that Cissus quadrangularis may improve insulin sensitivity, which is a critical factor in maintaining healthy body weight and metabolic function (Oben et al., 2006). These combined effects position cissus capsules as a potential adjunct to diet and exercise for individuals aiming to manage their weight effectively.
Exercise Recovery:
For individuals engaged in intense physical activity, cissus quadrangularis linn extract capsule may offer benefits in terms of exercise recovery. Its anti-inflammatory properties are thought to play a key role in mitigating exercise-induced muscle damage and inflammation. By reducing the extent of tissue damage and inflammation following strenuous exercise, Cissus quadrangularis extract may contribute to faster recovery and improved muscle function (Oben et al., 2006). This potential application could be particularly relevant for athletes and fitness enthusiasts seeking natural means to support their post-exercise recuperation.
Antioxidant Effects:
Cissus extract contains a range of bioactive compounds, including flavonoids and other antioxidants, which contribute to its overall health-promoting properties. These antioxidants are known for their ability to neutralize harmful free radicals and mitigate oxidative stress within the body (Jainu et al., 2006). By safeguarding cells from oxidative damage, Cissus quadrangularis extract supports overall health and well-being, potentially offering protective effects against various age-related and lifestyle-related health concerns.
References
Oben, J., Kuate, D., Agbor, G., Momo, C., & Talla, X. (2006). The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in Health and Disease, 5(1), 24. doi: 10.1186/1476-511X-5-24
Potu, B. K., Rao, M. S., Nampurath, G. K., Chamallamudi, M. R., Prasad, K., Nayak, S. R., & Dharmavarapu, P. K. (2009). Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis. Upsala Journal of Medical Sciences, 114(3), 140–148. doi: 10.1080/03009730902816979
Jainu, M., Mohan, K. V., & Devi, C. S. (2006). Protective effect of Cissus quadrangularis on neutrophil mediated tissue injury induced by aspirin in rats. Journal of Ethnopharmacology, 104(3), 302–305. doi: 10.1016/j.jep.2005.09.012
FAQ:Does Cissus capsules suppress appetite?
There is limited evidence to suggest that Cissus quadrangularis extract capsules have appetite-suppressing effects. While some animal studies have indicated that Cissus quadrangularis may reduce food intake and influence appetite-regulating hormones, the findings have not been replicated in human studies.
One study published in Lipids in Health and Disease in 2007 examined the effects of Cissus pills on body composition, metabolic rate, and appetite in overweight individuals. The randomized, double-blind, placebo-controlled trial involved 123 participants who were given either a placebo or 300 mg of Cissus quadrangularis extract twice daily for eight weeks. The researchers found no significant differences in appetite or food intake between the two groups (Oben et al., 2007).
Another study published in Phytotherapy Research in 2011 investigated the effects of a combination supplement containing cissus capsules, Irvingia gabonensis (a plant extract), and other ingredients on body weight and metabolic parameters in overweight and obese subjects. The randomized, double-blind, placebo-controlled trial involved 72 participants who were given either the supplement or a placebo for ten weeks. While the supplement group experienced significant reductions in body weight and waist circumference compared to the placebo group, there was no difference in appetite or food intake between the two groups (Ngondi et al., 2013).
Overall, the evidence on the appetite-suppressing effects of cissus quadrangularis capsules remains inconclusive and more research is needed to fully understand its potential effects in humans. Additionally, individual responses to Cissus quadrangularis extract can vary, and factors such as dosage and duration of use may influence its impact on appetite.
It's worth noting that while Cissus quadrangularis extract may not have significant appetite-suppressing effects, it has been studied for its potential benefits in promoting joint health, supporting bone healing, aiding in weight management, facilitating exercise recovery, and providing antioxidant support. However, as with any dietary supplement, individuals should seek guidance from healthcare professionals before incorporating cissus quadrangularis linn extract capsule into their wellness regimens.





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