Seaweed Polysaccharide

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of seaweed polysaccharide in China. Please feel free to wholesale high quality seaweed polysaccharide for sale here from our factory. For price consultation, contact us.

Seaweed polysaccharides are marine natural active polysaccharides, mainly from a mixture of multiple components of seaweeds such as kelp, deertail (amaranth), giant algae, vesicular algae, and musselweed. It can be divided into 4 major categories: brown algae polysaccharide, red algae polysaccharide, green algae polysaccharide and cyanobacterial polysaccharide. Algal polysaccharides are polymeric carbohydrates made of multiple identical or different monosaccharide groups connected by glycosidic bonds, which have high application value, such as agar, carrageenan and fucoidan have been used in industry for a long time. In addition, it has various effects such as immunomodulatory effect, antitumor effect, antimutagenic effect, induction of cell differentiation and antiviral.

The vast ocean, which covers 71% of the earth's total area, is rich in biological resources and is the largest producer of organic matter. Seaweeds (Algae or AeaweedsChemicalbook) are an important part of marine biological resources. Taxonomically, algae belong to the lower cryptogams and are divided into four main groups - cyanobacteria, green algae, red algae and brown algae, and also include diatoms, methanogens, golden algae and other microalgae. It is estimated that there are more than 15,000 species of seaweeds growing in the world's oceans. Seaweeds are the original producers of organic matter and natural enrichment of inorganic matter (including chlorine, bromine, iodine and other halogens) in the ocean ecosystem, it is at the bottom of the pyramid - eaten by predators, seaweeds and epiphytic, symbiotic microorganisms also exist in a complex antagonistic, symbiotic relationship, so seaweeds can often synthesize some cytotoxic, antibacterial and other activities of the The algae often synthesize some secondary metabolites with cytotoxic and antibacterial activities to adapt to survive and protect themselves. Seaweed is rich in polysaccharides, accounting for more than 50% of the dry weight of seaweed. Fucoidan, fucoidan and fucoidan starch crude products isolated from kelp are white and slightly yellow powder. The purified sodium fucoidan is a white filament; fucoidan is a milky white powder; both are soluble in water, insoluble in ethanol, acetone, chloroform and other organic solvents.

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seaweed polysaccharides extract is a kind of seaweed extract, seaweed belongs to lower plants, mainly divided into four categories: cyanobacteria, green algae, red algae and brown algae. Seaweed bioactive substances can be roughly divided into two kinds, one is the intercellular sticky polysaccharide which is difficult to be digested and absorbed, mainly including alginic acid, fucoidan in brown algae, agaric gum and carrageenan in red algae. The other is a small relative molecular mass, which can directly or indirectly affect the metabolic substances in the body after absorption, mainly including terpenoids, seaweed tannins, kombucha, etc. Seaweed Extract Powder is a multi-component mixture formed by different monosaccharide groups linked by glycosidic bonds (generally C1,3-bonds and C1,4-bonds), which is the general name of various polymeric carbohydrates contained in inter- and intracellular seaweed cells. Generally water-soluble, most of the large Chemicalbook contain sulfate groups and have the ability to be highly viscous or coagulated. There are many types of algal polysaccharides, which can be divided into red algal polysaccharides, green algal polysaccharides and fucoidan according to their sources, among which fucoidan has the most types and quantities. At present, the research on the structure of algal polysaccharides mainly focuses on the sugar units and contents they contain. For example, the polysaccharide of brown algae cell wall contains 25% L-fucose, 26% D-xylose, 19% D-glyoxylate, 13% sulfate and 12% protein. The molar ratio of L-fucose, sulfate, and acetate was 1:2.22:0.08, and the sugar chain structure was formed by the polymerization of several disaccharide units, with a relatively high content of sulfate, when the structural composition of some fragments was determined from brown algae.

Water extraction, acid extraction and alkali extraction: water extraction condition is 1h at 80 ℃ and repeat 3 times; acid extraction condition is 0.2 mol/L HCl at 60 ℃ 0.5h repeat 3 times; alkali extraction condition is 15%, 10%, 5% NaOH at 60 ℃ 0.5h. The extraction process to prevent polysaccharide degradation, so the acid and alkali methods of extraction temperature and time should be controlled. In order to improve the polysaccharide extraction Chemicalbook yield, according to the nature of polysaccharides, the application of some new separation and extraction techniques is also necessary, such as ultrasonic extraction, solvent-assisted extraction, double aqueous phase extraction, microwave extraction supplemented with enzymatic methods, or through molecular sieve or anion exchange column can achieve the purpose of polysaccharide and protein separation. To obtain polysaccharide pure products with higher purity, it is necessary to achieve it by high performance liquid chromatography, gas chromatography, capillary electrophoresis and other methods.

(1) Moisture-absorbing and moisturizing effect
Seaweed polysaccharides extract molecules contain a large number of hydrophilic groups such as hydroxyl and carboxyl groups, which can be combined with water molecules in the form of hydrogen bonds, so it has good hygroscopicity. The molecular chain of Seaweed Extract Powder and water molecules can be spatially cross-linked and entangled to form a network structure, so it has good moisturizing property.

(2) Antioxidant effect
The hemiacetal hydroxyl group in algal polysaccharide molecule has weak dissociation energy, which can provide electrons to oxidative radicals directly and quench them. Seaweed polysaccharide  extract can increase the activity of antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase and other enzymes to exert antioxidant effects.

(3)Whitening effect
Competitive inhibition: seaweed polysaccharide extract can compete with substrate for the active site of tyrosinase, such as chelating copper ion on the active site. Non-competitive inhibition: Algal polysaccharides can bind to tyrosine residues outside the active center of the enzyme, preventing further conversion of the substrate to the enzyme. Mixed inhibition: Some algal polysaccharides can bind to both the active site of the enzyme and the amino acid residues outside the active center.

(4) Bacteriostatic effect
Seaweed polysaccharide  extract has broad-spectrum bacterial inhibitory activity, and its inhibition mechanism is mainly based on good surface activity, which can bind to protein receptors on bacterial cell membranes and destroy phospholipids, proteins and fatty acids on bacterial membranes, and enhance the lysozyme's removal of bacteria. The molecular weight of rockweed polysaccharide below 6 kDa could inhibit the growth of Escherichia coli at a concentration of 8.00 mg/mL, and the growth of Staphylococcus aureus at a concentration of 6.25 mg/mL. After selenization modified marshmallow polysaccharide inhibition performance is better, marshmallow polysaccharide at a concentration of 6.80 mg/mL will inhibit the growth of Escherichia coli, Staphylococcus aureus, while selenized marshmallow polysaccharide inhibition of these two bacteria required concentration of only 1.70 mg/mL.

(5) Skin barrier repair
Seaweed polysaccharide  extract can activate the EPK and JNK signaling pathway by inducing EPK and JNK phosphorylation, promote the proliferation, migration and differentiation of skin keratinocytes, and accelerate the healing of skin wounds, thus repairing the skin barrier. Seaweed polysaccharide extract can promote the proliferation of human skin fibroblasts by activating cell growth factor, which can increase the synthesis and secretion of extracellular matrix such as hyaluronic acid and collagen fibers, thus repairing the skin barrier.

(6) Anti-UV radiation effect
Seaweed polysaccharide extract can improve the survival rate of skin fibroblasts after being damaged by UV radiation. Seaweed polysaccharide extract can strengthen the immunity of the body and resist the damage to the immune system caused by UV radiation. Seaweed polysaccharide extract can regulate the metabolism of collagen after UV radiation, and reduce the damage of skin by UV radiation.

Seaweed polysaccharide  extract has anti-viral, anti-tumor, anti-mutagenic, anti-radiation and immunity enhancing effects. Seaweed resources have a broad prospect of development and application in the fields of medicine, food, feed, chemical and cosmetics.

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