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1.What is Gynostemma pentaphyllum extract?
1.1 Introduction
Gynostemma Extract powder is the water extract or ethanol extract of the rhizome or whole plant of the traditional Chinese medicine Gynostemma pentaphyllum. The Gynostemma pentaphyllum extract is light yellow powder. The main active ingredient is Gypenoside. It has the effects of anti-inflammatory and detoxification, cough and expectorant.
It is a natural herbal extract derived from the leaves of the Gynostemma pentaphyllum plant, also known as the "miracle herb" or "sweet tea vine." This plant is native to Asia, particularly China, Japan, and Korea, and has been used for centuries in traditional Chinese medicine.
The extract is usually taken in supplement form and is believed to have a wide range of health benefits, including clearing away heat and detoxifying, replenishing qi, relieving cough and reducing phlegm. It has clinical anticancer effect. In addition, Jiaogulan extract can inhibit the proliferation of melanosarcoma and other cancer cells.
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1.2 Source plant
Gynostemma pentaphylla, also known as five-leaf ginseng and seven-leaf gallbladder, is called Ganman tea in Japan and belongs to a plant of Cucurbitaceae. Perennial climbing herb. The leaves are alternate, often 5 to 7 leaflets, and are bird-toed-shaped compound leaves; the central one is larger, the apex is acuminate, and the leaf margin is serrated. Yellow-white flowers in summer, axillary panicles, dioecious. Round berries; seeds as big as peas, dark purple when ripe.
It has the effects of clearing heat and detoxifying, relieving cough, clearing lung and eliminating phlegm, nourishing heart and calming nerves, nourishing qi and promoting essence. It can be used for lowering blood pressure, lowering blood fat, protecting liver, promoting sleep, and gastroenteritis, tracheitis, and pharyngitis. and used in the anticancer clinical treatment of various cancers. Gynostemma pentaphyllum has also been successfully made into Gynostemma pentaphyllum tea by tea processing enterprises all over China for sale in the market, and has gained considerable market share and considerable economic benefits.
1.3 Chemical composition
Gynostemma pentaphyllum contains a variety of medicinal ingredients: saponins, flavonoids, polysaccharides, amino acids, plant proteins, steroids, pigments, organic acids, trace elements, etc., and is known as "the fairy grass on earth".
2.Chemical & Physical Properties
|
CAS Number |
15588-68-8 |
Molecular Weight |
1791.83 |
|
Density |
1.6±0.1 g/cm3 |
Boiling Point |
N/A |
|
Molecular Formula |
C80H126O44 |
Melting Point |
N/A |
|
Common Name |
Gypsoside |
Flash Point |
N/A |
3.cOA
4.Benefits and Application
4.1 Health Benefits
According to the latest pharmacological experiments,Gynostemma pentaphyllum extract has the following effects on health:
Anti cancer effect: it can inhibit the proliferation of cancer cells such as liver cancer, lung cancer, uterine cancer and melanoma.
Anti aging effect: it can enhance the immune function of the body.
Hypolipidemic effect.
Other effects, Gynostemma pentaphyllum not only has the above pharmacological effects, but also has anti-tension, anti-stress, anti-ulcer, delaying body aging, promoting appetite, anti-hypoxia, anti-acute cerebral hemorrhage, anti-cold, cough and expectorant, hypnosis, analgesia , sedation, and memory-improving effects
4.2 Application
(1) Health products and food Gynostemma pentaphyllum can also be used to make medicinal wine, capsules and granules. Gynostemma health tea, Gynostemma drink, Gynostemma beer, Gynostemma sake, Gynostemma food additives, etc. have been developed and listed.
(2) Feed and additives In terms of animal husbandry, with the development of animal husbandry and aquaculture, the problems of medicines and feed additives have attracted people's attention. Can be used as medicine and food additive.can be antibacterial, improve immunity, can regulate the nervous system and endocrine activities, help to increase the appetite of poultry, livestock, fish and shrimp, etc., and improve feed utilization. It can be seen that Jiaogulan, as a plant-based feed additive, has a good development prospect for improving the resistance of livestock and poultry and preventing and controlling infectious diseases.
(3) Cosmetics have high development value in the cosmetics industry because of their anti-aging, hair blackening and beautifying effects. For example, mixing gypenoside with stearic acid can be used to prepare lotion, cosmetic ointment, soap, etc. Although the application research of Gynostemma pentaphyllum has gradually become a hot spot, many functions of Gynostemma pentaphyllum have not been fully utilized, so Gynostemma pentaphyllum has great development value and potential.
5.Extraction method of Gynostemma Extract powder
At present, the extraction techniques of effective components of Gynostemma pentaphyllum are mainly alcohol extraction and water extraction. Comparing the microwave alcohol extraction method and the water extraction method, the purity of the total saponins extracted by the former is higher, and the quality of the latter's bold substance is higher; the purification process includes resin column chromatography and petroleum ether extraction, etc., the former has high purification efficiency, The content of total saponin extracted by water extraction is higher, and the content of total saponin obtained by microwave alcohol extraction is higher. In addition, factors such as extraction temperature and extraction times are also obvious for the extraction of gypenoside, and are significantly greater than the extraction methods such as ethanol concentration and solid-liquid ratio.
6.Research and Application Status
In 1976, Japanese scientists extracted the total saponins of Jiaogulan from Jiaogulan. Gypenoside GP is a mixture of saponins extracted from plants of the genus Gypenoside. Its chemical components are complex, and its basic chemical structure has a dammarane structure similar to the skeleton of tetracyclic triterpenes of ginsenosides, and some of the components are exactly the same as ginsenosides. After extensive pharmacological research, it has been found that it has strong anti-arteriosclerosis and blood lipid-lowering effects, and most of the new drugs developed have this effect.
Since the folks in China have the habit of drinking Gynostemma pentaphyllum tea for a long time, many manufacturers are producing Gynostemma pentaphyllum health drinks, and there are not many companies extracting Gypenosides, but in recent years there have been some new drugs for lowering blood fat and treating cardiovascular diseases was developed.
Gynostemma Gynostemma has important medicinal value, and China is rich in medicinal resources, making full use of Gynostemma pentaphyllum to develop medicines and series of health care products will have broad prospects.
7. Our advantage
8.Kintai R&D room
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10.Contact us
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