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Esculin Hydrate

Esculin Hydrate

Extract source:Buckeye bark
Specification: 98% Esculin hydrate
Test Method:HPLC
CAS Registry No:531-75-9
Appearance:White acicular crystal powder
Certifications:GMP,ISO9001:2015,ISO22000:2018,HACCP,KOSHER and HALAL
MOQ:100g;
Sample:Free sample available
Delivery Time: Delivery within one day from warehouse
Shelf Life:Two years
Company Advantage:Kintai mainly focuses on the production of high-content plant extracts and pharmaceutical intermediates all year round.
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Product Introduction

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of esculin hydrate in China. Please feel free to wholesale high quality esculin hydrate for sale here from our factory. For price consultation, contact us.

 

Esculin Hydrate supplier

 

Esculin Hydrate is a natural plant active ingredient derived from Aesculus chinensis Bunge. Aesculus chinensis Bunge, also known as the saro, is a deciduous tree of the genus Aesculus in the Sapindaceae family. Its seeds, bark, leaves and other parts have long been used in traditional medicine. As an important active ingredient, Esculin Hydrate has become a popular raw material in many industries such as medicine, food, health care and cosmetics due to its unique pharmacological properties.

 

Esculin Hydrate Extract Source
Esculin Hydrate extract source
Esculin Hydrate Powder
Esculin Hydrate powder

Aesculus chinensis Bunge contains a variety of natural compounds with biological activity, especially Esculin, which shows significant activity in anti-inflammatory, antioxidant, antibacterial and anti-tumor aspects. Kintai uses the leaves of Aesculus chinensis as the main source and produces 98% Esculin Hydrate through a unique extraction and purification process to ensure its effectiveness in various applications.

 

Plant Source of  Esculin Hydrate

 

Specification of Esculin Hydrate

 

Product name

Esculin Hydrate

Extraction Solvent

Water/Ethyl alcohol

Appearance

White acicular crystal

Solubility

Soluble in hot alcohol, methanol, pyridine, ethyl acetate, and acetic acid (hydrate)

Identification

TLC, HPLC

Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay 

Min. 98.0%

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Shelf life

This product should be sealed and shaded, and stored in a dry, cool, and well-ventilated place. The validity period is 2 years

 

Production process of Esculin Hydrate


Kintai uses a combination of advanced resin purification and concentrated crystallization technology to significantly improve the purity and yield of Esculin Hydrate. During the production process, we refine the extracted mother liquor. Through concentration, dilution, filtration and other steps, select suitable resin materials (such as D101 or T-28 resin) for adsorption and desorption to ensure a high concentration of esculin in the extract.


Through this process, we can increase the purity of Esculin Hydrate to more than 80%, and at the same time recover the by-product quercetin, further improving production efficiency and product added value. The desorbed resin is further washed with high alcohol to obtain other by-products with medicinal value. This production process is efficient and green, and makes full use of every part of the raw materials.

 

product-931-556

 

Certificate

 

product-1920-2350

 

Benefits

 

Anti-inflammation effect: Echinocetin has a significant anti-inflammatory effect, which can inhibit the inflammatory response triggered by various channels. This is very beneficial in the treatment of inflammation-related diseases such as rheumatoid arthritis, inflammatory bowel disease, etc. A study published in the "Journal of Ethnopharmacology" explored the anti-inflammatory potential of acetraxin. The study found that echinocetin can effectively inhibit the production of various inflammatory mediators, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), thereby reducing the inflammatory response.

Anti-tumor effect: Studies have shown that fenpetrol has anti-tumor activity, can inhibit the growth and spread of tumor cells, and promote the apoptosis of tumor cells. This makes afracetin a potential candidate for the development of anticancer drugs. A study published in the "Journal of Ethnopharmacology" explored the anti-inflammatory potential of acetraxin. The study found that echinocetin can effectively inhibit the production of various inflammatory mediators, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), thereby reducing the inflammatory response.

 

Anti-tumor effect of Esculin Hydrate

 

Antioxidant effect: Esculin is an effective free radical scavenger. It neutralizes free radicals in the body, reduces oxidative stress, and maintains the normal function of cells. This helps prevent many diseases associated with oxidative stress, such as cardiovascular disease, neurodegenerative diseases, and more.

Antimicrobial effect: Alopecia has an inhibitory effect on a variety of bacteria, especially because it also shows good antibacterial activity on some drug-resistant strains. This makes it promising as an important component in the development of new antibacterial drugs. A research study published in the journal Antibiotics has shown that afraetin has antibacterial activity against a variety of bacteria. The study found that afracetin can effectively inhibit the growth of a variety of bacterial strains, including some drug-resistant strains.

Antimicrobial effect

 

Application

 

Pharmaceutical industry: Esculin powder can be used as a raw material for Chinese herbal medicines and used in traditional medicine formulas and preparations. It is believed to have anti-inflammatory, anti-tumor, antibacterial, and antioxidant properties, and thus can be used in the treatment of inflammatory diseases, tumors, and infections.

Food and health care products industry: Esculin powder can be added to food and health care products to enhance the antioxidant properties of the products. It can be used as a food additive such as an antioxidant and preservative to keep food fresh and stable during storage and processing.

Cosmetics industry: Due to its anti-inflammatory and anti-oxidative properties, Esculin can be used in skincare products and cosmetics. Alopecia powder can be used as an active ingredient in cosmetic formulations for reducing skin inflammation, anti-aging, and improving skin texture.

Agricultural field: Esculin powder can be used in the agricultural field as a plant protection agent. It inhibits the growth of phytopathogenic bacteria and provides an environmentally friendly method to control crop diseases without the use of chemical pesticides.

 

Dosage and Formulation

 

Dosage

For personal skin care or cosmetics, it is generally recommended to use escin hydrate powder at a concentration of 0.5%-2%.

The appropriate dosage should be determined according to the specific product type, desired efficacy, and individual characteristics, and follow relevant safety guidelines.

Reference formula

Here is a simple reference recipe that can be used as a starting point for using flax lignan powder for your reference: Soothing and repairing lotion

Element

Escin Hydrate Powder Mask Formula

1 g escin hydrate powder

20ml hyaluronic acid stock solution

10ml glycerin

5 drops of rose essential oil

Escin Hydrate Powder Eye Cream Formula

Escin Hydrate Powder Eye Cream Formula:

0.5g escin hydrate powder

10ml hyaluronic acid serum

5ml vitamin E oil

5ml strawberry seed oil

Note: These formulations are for reference only, and the specific dosage and formulation should be adjusted according to individual needs and skin conditions. When preparing and using any cosmetic product, always follow relevant regulatory and safety guidance and seek the advice of a professional cosmetic scientist or relevant professional.

 

why choose us?

 

 

Why choose Kintai.jpg

 

Kintai-Factory

 

Kintai-Factory

 

Kintai R&D center

 

Kintai R&D center

 

★KINTAI is committed to being your best Escin supplier. If you want to get high-quality Esculin Hydrate, please feel free to contact us at cheney@kintaibio.com or feedback on the next page.

 

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