D-biotin Powder

Product Details:

D-biotin powder is the eighth form of water-soluble vitamin B7. Coenzyme or coenzyme component used in many metabolic reactions of the body. D Chemicalbook.Biotin is involved in lipid and protein metabolism, helping to convert food into glucose that the body can use as energy. It is also important for the maintenance of skin, hair and mucous membrane.
Vitamin H and coenzyme R, also known as vitamins, are water-soluble vitamins and belong to vitamin B soldier B7. It is essential for the synthesis of vitamin C and for normal fat and protein metabolism. It is a nutrient required for the natural growth, development and maintenance of normal human function and health.
Biotin is one of the vitamin B groups, also known as vitamin H, vitamin B7, coenzyme R, etc. Vitamin B belongs to water-soluble vitamin B. It is more abundant in liver, kidney, yeast and milk, and is an important factor for the body to fix carbon dioxide. It is easy to combine with protein in egg white. Large intake of crude protein will hinder the absorption of vitamins, leading to hair loss, weight loss, dermatitis and other vitamin deficiencies. Vitamins play an important role in biochemical pathways such as fat synthesis and glucose production.
Viotine is the savior of baldness. It can not only prevent hair loss and luster on the top of the head, but also prevent the common white hair of modern people. It also plays an important role in maintaining skin health. Although the effect of stabilizing the nervous system has not been confirmed, it does help depression and insomnia.
Vitamin is the coenzyme of various decarboxylase, and plays the role of CO2 carrier in decarboxylase reaction.

Biotin is widely distributed in animals and plants, and the naturally occurring biotin exists mainly in the form of combinations with other molecules. The chemical structure of biotin includes a shuttle base side chain containing five carbon atoms and two five-headed heterocycles. In vivo, the shuttle base on the side chain is combined with the lysine s residue of the enzyme protein to play the role of coenzyme. Biotin can have eight different isomers, only DChemicalbook-Biotin being biologically active. In general, biotin is fairly stable and is only destroyed when treated with strong acid, strong alkali, formaldehyde, and ultraviolet light. Biotin is the carrier of the carboxyl group in many ATP-required carboxylation reactions, and the carboxyl group transiently binds to a nitrogen atom on the biotin bicyclic system, as in the carboxylation of pyruvate to oxaloacetate catalyzed by pyruvate carboxylase.

Physical and chemical properties: colorless to nearly colorless crystalline powder. The melting point is 232-233 ℃. Solubility at 25 ℃ (mg/100ml): water - 22; 95% ethanol - 80. Easily soluble in hot water and dilute alkali liquor, insoluble in other common organic solvents. It decomposes by strong alkali or oxidizer.

5.1 The main active ingredients of D-Biotin, which have many unique effects as below:

(1) Vitamin H is a key regulatory element for the heterogenesis of glycogen, the comprehensive effect of fatty acids and the metabolism of some amino acids, and can promote the synthesis of some proteins by helping to generate energy;

(2) At the same time, it can help cells grow, produce fatty acids, metabolize carbohydrates, fats and proteins, and help the utilization of vitamin B group;

(3) Promote the health of sweat glands, nervous tissues, bone marrow and male gonads;

(4) Maintain the normal operation and growth of skin and hair, and reduce eczema and dermatitis symptoms;

(5) Prevent white hair and hair loss, and help to treat baldness; Relieve muscle pain; It is really helpful for depression and insomnia;

(6) It also participates in the metabolism of vitamin B12, folic acid and pantothenic acid;

(7) Promote urea synthesis and excretion;

(8) Improve the immune function of the human body.

5.2 Application

Biotin, known as vitamin H, enables the body to convert food into its own energy. Biotin is beneficial to the health and regeneration of cells. Diabetes patients can improve the regulation of blood sugar through biotin. Biotin is also needed for the health of hair and nails.

1). Health use

(1) Diabetes. Biotin supplements help improve the regulation of blood sugar by improving the use of insulin and blood sugar.

(2) Hair and nails. Biotin supplements can repair weak and cracked toenails and fingernails, and improve hair health. Biotin can also repair gray hair that is prematurely caused by low levels of biotin.

(3) Genetic problems; Some infants cannot make good use of biotin and need to supplement biotin.

(4) Skin problems; Some skin diseases, such as milk scab, can be improved by supplementing biotin.

(5) Muscular dystrophy; Biotin can be used to treat certain muscle related diseases as part of the treatment course.

(6) Nutritional health; Biotin can help people who lose weight carry out more effective metabolism.

(7) Infectious diseases; Biotin can be used to treat intestinal candidiasis, an infection of yeast.

(8) According to research, folic acid and biotin can effectively prevent teratogenesis. 

(9) American researchers also found that biotin can promote the decomposition of fats and carbohydrates, so that they can be quickly converted into energy needed for human activities; When the amount of biotin in the body is insufficient, fat accumulates in the body, and causes obesity.This new discovery has laid a solid foundation for the application of biotin in weight loss and slimming health products, and opened up a broader market for biotin.

2). Beauty use

(1) Japanese scholars reported that biotin has excellent cosmetic effect, which can keep skin white and nails smooth. This finding also opens a new pharmaceutical application of biotin products.The beauty and cosmetics industry is one of the major international industries. The total sales volume of the international market of beauty and cosmetics is far higher than the sales volume of drugs. The new application of biotin in skin, nail (nail) and hair beauty will inevitably lead to an increase in the sales volume of pharmaceutical grade biotin.

(2) Vitamin H is used as a nutritional supplement. According to Chinese GB2760-90, it can be used in food industry as processing aids.A large amount of raw protein can lead to biotin deficiency.

(3) For cosmetics, it can improve the speed of blood circulation in the skin blood vessels, and is easy to mix the oil phase in the formula within the concentration range of 0.1%~1.0%. It can be used in skin care cream, sports medicine liquid, foot pain relieving cream, shaving liquid and shampoo.

3). As a drug, it is used to treat arteriosclerosis, stroke, dyslipidemia, hypertension, coronary heart disease and blood circulation disorders.

4). Scientific research purpose

Biotin can be used in the nucleic acid industry. It can bind to the UTP or the C at the 5 'position of dUTP of nucleic acid molecule, and can be detected by binding with avidin. In the process of detection, biotin is only used for fixed connection, not for signal detection.

Biotin, as the coenzyme of acetylide-CoA shuttlease, participates in the synthesis of fatty acids, and catalyzes the formation of malonate CoA from acetylidene CoA. This reaction is the first step of fatty acid synthesis, and then through the cytoplasmic multi-enzyme complex and fatty acid synthase, palmitic acid is synthesized from malondiphthalein-CoA. In the elongation reaction of fatty acid carbon chain, malondiphthalein-ACP participates in the reaction as a donor of two carbon units, and malondiphthalein-ACP is derived from malondiphthalein-CoA. It can be seen that biotin plays an important role in the initiation of fatty acid synthesis. And the elongation of fatty acid carbon chain is necessary. Biotin deficiency and abnormal lipid metabolism cause changes in the fatty acid composition of the body, decrease in the synthesis of saturated fatty acids, increase in the synthesis of triphthalglycerol, and increase the fat content in the liver and kidney by 2 to 5 times. Biotin-deficient diets increased the rate of palmitic acid desaturation in liver tissue by a factor of five. Palm oleic acid increases, stearic acid decreases, and biotin is also an essential substance for the normal synthesis of long-chain unsaturated fatty acids and fatty acid metabolism. 

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