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1.What is Aloe vera extract?
Aloe Vera Barbadensis Leaf Extract is a colorless, transparent to brown, slightly viscous liquid and becomes a yellow fine powder after drying. No or slight odor. Has strong moisturizing properties.
The anthraquinone compounds of aloe have astringent, softening, moisturizing, anti-inflammatory and skin bleaching properties. It can also relieve hardening and cornification and improve scarring. It can not only prevent small wrinkles, bags and sagging skin, but also keep the skin moist and tender. It also has a good healing effect on wounds and insect bites. It is also effective on the hair, which can keep the hair moist and smooth and prevent hair loss.
After the aloe vera extract has been processed into aloe vera gel, it can be applied to the skin.It contains other moisturizing factors that can restore moisture to the skin and help improve the symptoms of dry skin. In addition, it can also form a water-binding film on the skin, which helps reduce water loss in the skin and help the skin become supple and shiny.
When aloe vera extract acts on the intestinal tract, it can help relieve digestive disorders caused by acute enteritis, colitis, proctitis and other diseases. It can also improve symptoms such as increased stool frequency and diarrhea and can also be used to support treatment local inflammation of the intestine.

1.1 Source plant
Aloe vera has therapeutic effects such as detoxification, hemostasis, anti-infection and anti-tumor. Ancient medical books such as "Ben Jing Feng Yuan" report that aloe treats children with "contagious malnutrition and heat stagnation, which cannot be cured without treatment." "Aloe contains aloe-emodin, which has the effect of resisting pathogenic microorganisms. Angelica Aloe Vera Pills have a certain therapeutic effect on chronic myelogenous leukemia. According to foreign literature reports, aloe extract can promote the regeneration and healing of damaged tissues, including X-ray burns, and has pharmacological effects such as detoxification. ng, lowering blood fat, anti Atherosclerosis and promotion of hematopoietic recovery in experimental anemia.
Aloe (scientific name: Aloe Vera): is a perennial evergreen herb of Liliaceae and Liliaceae. Also known as Curacao Aloe, Chinese Aloe, Onion, Aloe, Aloe, American Aloe, etc. The leaves are grouped, large and thick, sitting on or at the tip of the stem, and the leaves are usually lanceolate or short and wide, with sharp spines on the edge. Inflorescences are umbels, grapes, ears, cones, etc. , red, yellow or speckled with red, with six petals and six stamps. The bottom of the flower envelope is joined several times to form a tube.
1.2 Active substances in aloe vera extract
Aloe vera stems and leaves are rich in anthraquinones, and others include vitamins, polysaccharides, and essential amino acids. Anthraquinone compounds include aloin, aloe-emodin, isoaloein, emodin, rhubarb root acid, etc.; vitamins include vitamin B1, folic acid, vitamin B2, vitamin C, niacinamide, vitamin E, vitamin B6, vitamin choline and β-carotene; essential amino acids include lysine, leucine, threonine, isoleucine, phenylalanine, valine, etc. It also contains aloe vera, aloe polysaccharide and so on.
2.Benefits and Application
2.1 Health Benefits
According to the latest pharmacological experiments, Aloe vera barbadensis leaf extract has the following effects on health:
2.1.1 Bactericidal and anti-inflammatory effects
Aloe vera extract contains anthraquinone compounds, which can reduce inflammation and inhibit bacteria to a certain extent, and can help improve skin inflammatory lesions. After being applied to the wound, it can also promote wound healing.
2.1.2 Stomach strengthening and laxative effect
When the aloe extract acts on the intestinal tract, it has the effect of invigorating the stomach and laxative, and plays the role of increasing appetite and large intestine laxative. It can help relieve indigestion symptoms caused by acute enteritis, colitis, proctitis and other diseases.
2.1.3 Anti cancer effect
Aloe extract has inhibitory effect on sarcoma sl80 and Ehrlich ascites carcinoma. The active ingredients of aloe vera can not only prevent the growth of cancer cells, but also kill bacteria, neutralize exotoxins, and significantly improve the immune function of the body.
2.1.4 Beauty efficacy
In the application of cosmetics, there are records of aloe vera as a beauty product in ancient my country. Aloe vera juice is a natural extract, which contains a variety of moisturizing ingredients and nutrients that are beneficial to the human body. According to scientific research, because aloe vera contains glucose, mannose, uronic acid, calcium, hydratase, biological hormones, hormones, proteins, amino acids, vitamins, minerals and other trace elements, it has nutritional moisturizing, sunscreen, hang inflammation, At the same time, it has significant effects on softening the skin, astringent, preventing acne, preventing rough skin, anti-inflammatory and anti-itching, hair care, and keeping the skin tender and white. Aloe vera has good compatibility, can cooperate well with various cosmetic crystal raw materials, and can eliminate the damage of various surfactants to the skin. Cosmetics made with aloe extracts include health toothpaste, skin cleansing and skin care products, series of hair products, moisturizing cream, youth cream and other products. According to the report of the American Cosmetic Association, aloe vera is the most popular cosmetic in the United States, with more than 33% of consumers Use this makeup.
2.1.5 Enhance the immunity of the body
Regulate human immunity (resistance), aloin A, wound hormones and polysaccharide peptide manna (Ke-2) have anti-viral infection, promote wound healing and recovery, anti-inflammatory and bactericidal, heat-clearing and swelling, softening the skin, The function of maintaining cell viability, curdlan combined with callicoic acid also has wound healing activity.

aloe vera

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2.2 Application
Aloe vera extract is widely used in medical care, beauty and skin care, and health food therapy.

3.Chemical & Physical Properties
|
CAS Number |
1415-73-2 |
Molecular Weight |
418.394 |
|
Density |
1.6±0.1 g/cm3 |
Boiling Point |
752.6±60.0 °C at 760 mmHg |
|
Molecular Formula |
C21H22O9 |
Melting Point |
148-149ºC |
|
Common Name |
Aloin |
Flash Point |
268.0±26.4 °C |
4.Determination of Aloe Vera by RP-HPLC
【Instruments and reagents】
American Waters501 pump, U6K sample injector, American Beckman163 variable wavelength ultraviolet detector and 427 integral recorder; the ultraviolet absorption spectrum was determined by Hitachi 557 spectrophotometer.
Acetonitrile: chromatography pure; water: Millipore-Q filtered high-purity water; trifluoroacetic acid: Merck reagent; aloin standard crystal.
【Chromatographic conditions】
American SUPELCOLC-18 column (250mm×4.6mm, 5μm), column temperature is room temperature; mobile phase: acetonitrile-0.01moL/L trifluoroacetic acid (22:78), flow rate: 1.0mL/min; detection wavelength: 359nm, detection Sensitivity: 0.05AUFS; injection volume: 10μL.
【Standard curve preparation】
Accurately weigh an appropriate amount (about 12.5mg) of aloin standard substance dried to constant weight, put it in a 20mL volumetric flask, add methanol to dissolve to the mark, shake well, and make a 0.5mg/mL solution; Put 2.0mL, 3.0mL, 4.0mL, 5.0mL in a 10mL volumetric flask, add methanol to dilute to the mark, and shake well. Inject the sample to measure the absorbance.
【Sample measurement】
Accurately weigh 50 mg of the sample, put it in a 50 mL volumetric flask, add 45 mL of methanol, ultrasonically extract for 30 min, add methanol to dissolve to the mark, and shake well. Filter through a 0.45 μm microporous membrane, take the filtrate and measure it according to the standard method, and calculate the aloin content of the sample by the external standard method.

5.Product quality specification & standard
|
Product name |
Aloe vera extract |
|
Extract source |
Aloe vera, aloe vera of Cape of Good Hope or aloe vera leaf of Liliaceae |
|
Extraction Solvent |
Ethyl alcohol |
|
Appearance |
Yellow or yellowish powder |
|
Solubility |
Soluble in pyridine, glacial acetic acid, formic acid, acetone, methyl acetate, ethanol, etc |
|
Identification |
TLC , HPLC |
|
Sulphated Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay of Aloe vera extract (HPLC test, percent, Standard in House) |
Min. 95.0% |
|
Residual Solvents |
|
|
- N-hexane |
NMT 290 PPM |
|
- Methanol |
NMT 3000 PPM |
|
- Acetone |
NMT 5000 PPM |
|
- Ethyl Acetate |
NMT 5000 PPM |
|
- Ethanol |
NMT 5000 PPM |
|
Pesticide Residues |
|
|
- Total DDT (Sum of p,p'-DDD,P,P'-DDE,o,p'-DDT and p,p' -DDT) |
NMT 0.05 PPM |
|
- Aldrin, Endrin, Dieldrin |
NMT 0.01 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China |
|
Shelf life |
24 months |
6. Aloe Vera Barbadensis Leaf Extract Extraction Process

7. Production process

8.Kintai-Factory

9.Kintai R&D room

10.Parcel delivery

12.Contact us
★If you want to get high quality Aloe Vera Barbadensis Leaf Extract, please feel free to contact us at cheney@kintaibio.com or feedback in next page.
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