Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of Nicotinamide Riboside NR powder in China. Please feel free to wholesale high quality Nicotinamide Riboside NR powder for sale here from our factory. For price consultation, contact us.
Nicotinamide Riboside NR powder Suppliers/manufacturer
Nicotinamide nucleoside (NR) is a higher form of vitamin B3 and a highly efficient precursor to nicotinamide adenine dinucleotide (NAD+). NAD+ is a key coenzyme involved in energy metabolism, DNA repair, and gene expression regulation within cells, supporting healthy aging by enhancing mitochondrial function and promoting cell repair and DNA maintenance.
However, NR is present in extremely small amounts in natural foods (such as some meats and milk), making it difficult to obtain effective doses through daily diet. Preclinical studies have shown that Nicotinamide Riboside NR Powder has potential in improving metabolic function, neuroprotection, and cardiovascular health, and exploratory applications have been initiated for neurodegenerative diseases and metabolic syndrome.
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KINTAIBIO®'s NRCl powder is currently the most widely adopted and recognized standard form of NR raw material in the global nutritional supplement industry. The main specification is NRCl ≥ 99%, and its production process is mature, converting NR into a more stable crystalline structure through a salt-forming process. This form has undergone comprehensive safety assessments and has obtained independent "Generally Recognized As Safe (GRAS)" certification from the US FDA, providing a solid guarantee for the safety and compliance of the end product.
In terms of biological function, Nicotinamide Riboside Chloride is completely equivalent to NR. Upon entering the body, chloride ions separate, releasing NR molecules, which are then efficiently converted to NAD+ via the same NRK enzyme pathway. The vast majority of studies on NR's ability to increase NAD+ levels and its potential health benefits use NRCl as the raw material, and its effectiveness and reliability have been validated by the market over a long period.
Our liposomal nicotinamide riboside powder is a lyophilized powder prepared using advanced liposome encapsulation technology. The main specifications include Liposomal Nicotinamide Riboside 10% and 20%. Encapsulating high-purity NR (or NRCl) within liposomes significantly improves its absorption rate and bioavailability. Key indicators include high encapsulation efficiency, controllable particle size distribution (nanoscale), and excellent reconstitution and dispersibility.
TDS Of Nicotinamide Riboside NR Powder
| ITEMS | SPECIFICATION | TEST METHOD |
| Appearance | white Powder | Visual |
| Particle Size | >95% through 80 mesh | Screening |
| Residue on Igniton | ≤0.5g100g | 3g/550℃/4hrs |
| Loss on Drying | ≤3.0g100g | 3g/105℃/2hrs |
| Bulk Density | 0.2-0.5gm1 | Average Bulk Density |
| Identification | Consistent with the control map | IR |
| PH | 2.0-4.0 | 3.5 |
| Purity | ≥99% | HPLC |
| Residue Analysis | ||
| Ethanol Solvent Residue | ≤1000mgkg | / |
| Lead(Pb) | ≤0.50mg/kg | ICP-MS |
| Arsenic(As) | ≤0.50mg/kg | ICP-MS |
| Cadmium(Cd) | ≤0.50mg/kg | ICP-MS |
| Mercury (Hg) | ≤0.50mg/kg | ICP-MS |
| Total Plate Count | ≤1000cfu/g | AOAC 990.12 |
| Total Yeast &Mold | ≤100cfu/g | AOAC 991.02 |
| E.Coli. | Negative/10g | AOAC 997.14 |
| Salmonella | Negative/10g | AOAC 998.09 |
| S.aureus | Negative/10g | AOAC 2003.07 |
| Storage | Transport at room temperature, keep the seal at 0-5 'C for a long time, away from strong light and heat source. | |
| Shelf life | 24month | |
Nicotinamide Riboside NR powder benefits
Nicotinamide Riboside NR powder benefits for skin
Based on the latest cell biology research, Nicotinamide Riboside NR Powder has shown significant potential in the fields of skin health and photoaging protection. As a highly effective precursor to NAD+, NR can penetrate deep into the skin cell level: studies have shown that in a skin cell model exposed to ultraviolet (UVB) radiation, NR treatment effectively inhibits melanin production stimulated by α-melanocyte-stimulating hormone and functionally reduces pigmentation by decreasing tyrosinase activity-a key step in melanin synthesis.
Source:https://www.mdpi.com
Simultaneously, NR can alleviate UV-induced damage to keratinocytes and inhibit the overexpression of related matrix metalloproteinase genes, thereby helping to maintain the integrity and elasticity of the skin barrier. This evidence makes it a scientifically based, endogenous skincare active ingredient that addresses cellular energy metabolism, suitable for the development of high-end anti-photoaging and skin brightening skincare products.
Nicotinamide Riboside NR powder and cancer
The potential of Nicotinamide Riboside NR Powder in cancer prevention and treatment is equally significant. NR can specifically activate the key mitochondrial deacetylase SIRT3 by increasing intracellular NAD+ levels. In research models of malignant tumors such as pancreatic ductal adenocarcinoma (PDAC), downregulation of SIRT3 activity is closely related to disease progression, and NR supplementation can restore SIRT3 function in a SIRT3-dependent manner, thereby regulating the mitochondrial metabolic network and delaying the transformation of precancerous lesions into tumors.
Source:https://www.sciencedirect.com
More importantly, NR has shown synergistic effects with standard chemotherapy drugs (such as gemcitabine), significantly enhancing chemotherapy-induced tumor cell death in preclinical studies, suggesting its potential as a promising metabolic adjuvant strategy, providing a new scientific perspective for improving treatment efficacy and addressing drug resistance. These findings provide an important preliminary research foundation for the development of adjuvant health products based on NR metabolic regulation.
Nicotinamide Riboside NR powder weight loss
In an animal model of metabolic disorder induced by a high-fructose diet, Nicotinamide Riboside NR Powder effectively slowed weight gain and significantly reduced white adipose tissue accumulation and liver weight. Its mechanism of action is closely related to the activation of the SIRT1/AMPK signaling pathway, which promotes the "browning" of white adipose tissue-its transformation from a stored energy form to a consumed energy form-thereby increasing overall energy metabolism.
Source:https://www.mdpi.com
Simultaneously, NR intervention helped reduce lipid levels in serum and liver, suggesting its potential benefit in maintaining a healthy lipid profile. Furthermore, the study found that NR supplementation was associated with changes in the abundance of specific beneficial gut microbiota, which may be another way it indirectly supports metabolic health. This demonstrates that Nicotinamide Riboside NR Powder, through multi-target regulation, provides a scientific approach based on cellular energy metabolism to address the challenges of weight and lipid management brought about by modern dietary patterns.
Reference:https://www.mdpi.com/2079-9284/11/3/73
https://www.sciencedirect.com/science/article/abs/pii/S0006295225008500
https://www.mdpi.com/2072-6643/16/22/3920
what is Nicotinamide Riboside NR powder for?
Nicotinamide Riboside NR powder supplement
In the realm of oral supplements,Nicotinamide Riboside NR Powder, in capsule and tablet forms, are the mainstream choice for dietary supplements, with their main ingredient often being the more stable nicotinamide nucleoside chloride (NRCl) powder. In recent years, NR powder supplements utilizing liposome technology have garnered significant attention in the high-end market due to their ability to significantly improve bioavailability. These products primarily serve consumers seeking to delay aging, enhance cellular energy metabolism, and improve overall health.
Nicotinamide Riboside NR powder cream
In the topical field, Nicotinamide Riboside NR Powder is also beginning to be used in high-end skincare products. Creams and serums containing it aim to leverage its ability to boost NAD+ levels in skin cells, acting on the skin to help combat photoaging, improve skin tone, and promote skin repair. Whether taken internally or applied topically, it demonstrates diverse application potential based on cellular energy metabolism.
side effects Nicotinamide Riboside NR powder
Nicotinamide riboside (NR) has been reported to be generally well tolerated at daily doses ranging from 500 mg to 2,000 mg. Mild to moderate side effects may include nausea, headache, fatigue, and gastrointestinal upset (usually limited to stomach pain, diarrhea, and indigestion).
Furthermore, the nicotinamide riboside chloride component is labeled as generally recognized as safe (GRAS) by the U.S. Food and Drug Administration.
Nicotinamide Riboside NR powder where to buy?
As a professional Nicotinamide Riboside NR Powder manufacturer, KINTAIBIO®'s high-quality nicotinamide nucleoside chloride typically boasts a purity of 99% or higher. We not only offer the best competitive pricing in the market but also rely on superior quality control as our cornerstone. Our entire production process adheres to stringent quality management systems, including GMP, ISO9001:2015, ISO22000:2018, and HACCP, ensuring compliance and controllability at every stage from raw materials to finished products.
Each batch of Nicotinamide Riboside NR Powder comes with a detailed Certificate of Analysis (COA), guaranteeing purity, safety, and clear traceability, providing solid and reliable backend support for you to create your own brand of NR supplements. If you wish to purchase high-quality nicotinamide nucleoside chloride powder, please feel free to contact us at sales@kintaibio.com or leave feedback on the next page.
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