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What is NMN Nicotinamide Mononucleitide?
β-Nicotinamide Mononucleotide is a biomolecule also known as NAD. It is synthesized from nicotinamide and adenine dinucleotide through a series of chemical reactions. As an important cofactor, nicotinamide mononucleotide exists widely in organisms and participates in many key biological processes, including energy metabolism, DNA repair, and signal transduction. In addition, nicotinamide mononucleotide also has antioxidant effects, which can protect cells from damage by oxygen free radicals. In medical research, nicotinamide mononucleotide is also an important research object because it is closely related to the occurrence and development of many diseases, such as cancer, diabetes, and neurodegenerative diseases.

In recent years, NMN and its derivatives have been widely used in the treatment of cardiovascular diseases, cancer, neurometabolic diseases, and other diseases, and will become one of the important research directions in the field of life sciences in the future.
Physicochemical properties
| CAS Number | 1094-61-7 | Molecular Weight | 334.219 |
| Density | N/A | Boiling Point | N/A |
| Molecular Formula | C11H15N2O8P | Melting Point | N/A |
| Common Name | β-Nicotinamide mononucleotide | Flash Point | N/A |

Specification
|
Product Name |
Beta Nicotinamide Mononucleotide |
|
Assay(HPLC) |
≥99.0% |
|
Appearance |
White Powder |
|
Particle Size |
100% pass 40 mesh |
|
Ethanol(GC) |
0.020% |
|
Heavy Metals |
|
|
Lead(Pb) |
≤0.5ppm |
|
Arsenic(As) |
≤0.5ppm |
|
Mercury(Hg) |
≤0.5ppm |
|
Cadmium(Cd) |
≤0.5ppm |
|
Microbiological Tests |
|
|
Total Microbial Count |
≤750cfu/g |
|
Coliforms |
≤3.0MPN/g |
|
Conclusion |
Conforms to the In-house Standard |
What is the source of NMN?
- A: NMN is a natural substance in the human body and some foods, which can participate in various biological reactions. In the human body, NMN is mainly converted from ribonucleotides (RNA) and nucleic acid hydrolysis products (NAD+) ingested in food. When the body needs NAD + for energy metabolism and DNA repair, NMN will be synthesized and then converted into NAD + to enter the metabolic process of cells.
- B: NMN can also be ingested through certain foods such as milk, asparagus, and tomatoes.
- C: NMN is also found in some plants, including Viola Rutaceae, which can positively affect the human body through antioxidant and vasodilation effects.

Why does the human body need to supplement NMN?
NMN can participate in the process of cellular energy metabolism, helping cells generate enough ATP to supply the body's various metabolic and biological activities. With age, the content of NAD + (the precursor of NMN) in the human body gradually decreases, which leads to a series of aging and metabolism-related problems.
The supplementation of NMN can help increase the content of NAD +, thereby improving the energy metabolism of cells, delaying the aging process, and maintaining the health of the body. In addition, NMN also has other important biological and therapeutic applications, such as improving cellular DNA repair function, regulating the cAMP signaling pathway, enhancing immune system resistance, reducing inflammatory response, etc. Therefore, the human body needs to supplement NMN powder to increase the NAD + content, which will better meet the needs of the body's various metabolic and biological activities, and can also slow down the aging process and maintain the body's health.
NMN Nicotinamide Mononucleotide Benefits
1. Anti-aging function.
As a precursor of NAD+, NMN can promote the increase of NAD+ levels in cells. NAD+ is an important energy substance in cells, participates in many metabolic pathways, and is widely used in many aspects such as energy metabolism, DNA repair, and neuron homeostasis. However, with age, the level of NAD+ in the human body will gradually decrease, which will lead to the decline of cell function and the occurrence of aging. The supplementation of NMN can increase the level of NAD+ in cells, thereby preventing the occurrence of aging, and can also increase the ability of cell metabolism to improve the self-repair ability of cells.
2. Enhance immunity.
NMN has a certain effect on improving human immunity. Researchers have found that NMN can increase the number of lymphocytes and monocytes, increase the activity of NK cells, and enhance the lethality of NK cells, thereby enhancing the body's disease resistance. Moreover, NMN can also increase the production of GSH in the human body, and activate the activity of glutathione peroxidase, thereby enhancing the antioxidant capacity. In addition, NMN also has a certain regulatory role in pathological metabolic reactions such as inflammatory reactions and cell apoptosis.

3. Improve cardiovascular and cerebrovascular diseases.
NMN can stimulate endothelial cells to synthesize NO, promote blood vessel expansion, and strengthen blood circulation, thereby lowering blood pressure and improving cardiovascular and cerebrovascular diseases. Studies have found that NMN supplementation can increase the activity of angiotensin-converting enzyme 2 (ACE2), reduce the level of angiotensin II (Ang II) in the blood, reduce inflammation and vascular tension, and delay the progression of vascular aging and atherosclerosis. occur. At the same time, NMN can also stimulate dopamine D1 receptors, reduce heart pressure and pain, and relieve symptoms of coronary heart disease and other diseases.

4. Enhance muscle strength.
NMN can increase the level of muscle growth factor (IGF-1), and increase the protein content of muscles in the body, thereby increasing muscle strength and endurance, and promoting muscle repair. At the same time, NMN can also inhibit the production of key inflammatory factors, and reduce muscle pain and damage.
Dosage & Formulation
Generally speaking, for healthy adults, the recommended daily oral dose of NMN powder is 1000 mg to 1500 mg, taken in divided doses. At the same time, sufficient water intake should be ensured to promote the absorption and utilization of NMN. For people who are older or have other diseases, the dosage and formula of NMN powder can be customized under the guidance of a professional doctor or nutritionist to ensure its safety and effectiveness.
The vitamin B family is one of the necessary components for the human body to synthesize NAD+, which can improve the effect of NMN powder. It is recommended to add additional vitamin B nutrients, such as vitamin B1, B2, B3, B6, and B12, on the basis of NMN powder dosage, to assist the synthesis of NAD+.
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