Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of macleaya cordata extract in China. Please feel free to wholesale high quality macleaya cordata extract for sale here from our factory. For price consultation, contact us.
Macleaya cordata extract Powder manufacturer
KINTAIBIO®'s Macleaya cordata extract powder (MCE) is derived from the dried pods of the plume poppy plant Macleaya cordata. Macleaya cordata has a medicinal history of at least 1200 years in traditional Chinese medicine, where it is believed to possess insecticidal, detoxifying, and anti-inflammatory properties. Modern scientific research has revealed its active nature, identifying 147 alkaloids, with sanguisorbin, Chelerythrine, allocinine, and protopine being the four isoquinoline alkaloids present in the highest concentrations.
Total Alkaloids 60% (Sanguinarine>40%,chelerythrine>15%)
Macleaya cordata Extract
Regarding specifications, our Macleaya cordata extract powder adheres to a core standard of at least 60% total alkaloid content (HPLC), with sanguisorbin exceeding 40% and celandine exceeding 15%. This quantitative indicator ensures the stable performance of the product's biological efficacy. Under a rigorous quality control system, we provide standardized products and can also customize production according to customer formulation requirements, focusing on key indicators such as sanguisorbin, to meet the precise requirements of different application scenarios.
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In application areas, our plume poppy macleaya cordata extract powder demonstrates multiple values. In animal husbandry, it effectively improves livestock and poultry production performance and health by inhibiting harmful bacteria, alleviating inflammation, enhancing immunity, and improving liver function. In clinical medicine and biopesticides, its potential for insecticidal, maggot-killing, and anti-tumor effects is receiving increasing attention. For further consultation or customization, please feel free to contact our sales team: Sales@Kintaibio.Com.
The extraction source of Macleaya Cordata Extract (MCE)
KINTAIBIO®'s raw materials are carefully selected from the mature pods of premium herb from Northeast China. The unique cold-temperate continental climate of this region, coupled with fertile soil, provides ideal natural conditions for the growth of plume poppy, particularly conducive to the natural enrichment and accumulation of core alkaloid components (such as sanguisorbin and celandine) in the fruit, thus providing a highly active material basis for the extract.
To control product quality and stability from the source, we strictly regulate seed sourcing to ensure superior germplasm quality, adhere to pesticide residue-free safety requirements throughout the process, and eliminate exogenous contamination at the source. We precisely grasp the optimal harvesting time for mature pods to ensure that the active ingredients in the raw materials are at their peak.
Each batch of raw materials entering the production process undergoes rigorous incoming inspection, testing for the content of core alkaloids and safety indicators such as pesticide residues and heavy metals. Simultaneously, we have established a complete batch traceability information file for each batch of raw materials. It is this high level of attention and meticulous management at the source that ultimately ensures the stability and reliability of our Macleaya Cordata Extract in terms of purity, active ingredient content, and long-term supply, providing a solid guarantee for our customers' applications.
How To Make Macleaya Cordata Extract?
Macleaya Cordata Extract Production process flow chart
Crush pods → Remove impurities → Dry → Acidic extraction → Filter → Make alkaline → Filter → Dissolve in ethanol → Filter → Concentrate → Dry → Crush extract.
COA of Macleaya Cordata Extract
Our Macleaya Cordata Extract testing projects include, but are not limited to:
- Total alkaloid content (HPLC method) Testing the main active ingredients of benzophenanthridine alkaloids
- Sanguinarine and chelerythrine content (HPLC method)
- Water
- Heavy metals (lead, arsenic, cadmium, mercury)
- Microbial indicators (Salmonella, total mold, etc.)
We will provide you with a complete quality inspection report (COA) for each batch. The following is pre-COA.
2025 testing technology update
We mainly use UPLC-ESI-MS coupling technology (ultra-high performance liquid chromatography-mass spectrometry) for component analysis. Its sensitivity: 0.01 μg/mL is 3 times that of conventional HPLC. The consumption of solvents is 60% lower than that of HPLC.
Quality control
To ensure batch consistency, we have tested the active ingredient content of production data for 12 consecutive months, and the fluctuation range is ≤ ±5%.For more detailed HPLC and UPLC-ESI-MS detection method documents, please contact sales@kintaibio.com to obtain them.
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Macleaya Cordata Extract benefits
Based on scientific research and experimental data, the observed biological activities of Macleaya Cordata Extract are:
Macleaya Cordata Extract Antibacterial and Antiviral
According to recent research, adding Macleaya Cordata Extract to the diet of British Shorthair cats can effectively regulate their gut microbiota structure and inhibit the proliferation of potentially harmful bacteria. Research data showed that the relative abundance of conditionally pathogenic bacteria in the feces of cats in the Macleaya Cordata Extract group was significantly reduced. These bacteria are closely related to intestinal inflammation and infection, and their decrease in abundance directly reflects the improvement of the gut microecological environment.
Source:https://www.mdpi.com
Further correlation analysis showed that the reduction of these harmful bacteria was positively correlated with the improvement of the body's antioxidant capacity and immune indicators, while negatively correlated with the level of pro-inflammatory cytokines. This finding scientifically reveals that macleaya cordata plume poppy Extract not only exerts its dual effects of antibacterial and intestinal health care by directly inhibiting pathogenic bacteria, but also by reshaping a healthy gut microbiota balance and reducing the risk of inflammation.
Macleaya Cordata Extract Antioxidant Activity
The antioxidant efficacy of Macleaya Cordata total alkali extract powder has recently been further confirmed by authoritative research. Research data showed that supplementing broiler chicken diets with Macleaya Cordata Extract resulted in positive changes in key antioxidant indicators in serum. This indicates that Macleaya Cordata Extract can effectively activate the body's enzymatic antioxidant system and enhance the body's ability to scavenge free radicals.
Source:https://www.mdpi.com
When Macleaya Cordata Extract is used synergistically with other natural ingredients, its antioxidant effect shows even greater potential, further enhancing total antioxidant capacity and reducing pro-inflammatory cytokine levels. This scientific discovery confirms that Macleaya Cordata Extract reduces oxidative damage and maintains healthy homeostasis at the cellular level through a synergistic regulatory mechanism of "antioxidant-immunity-inflammation."
Macleaya Cordata Extract Anti-inflammatory
A study demonstrated that adding Macleaya Cordata Extract to the diets of newborn piglets exhibited excellent anti-inflammatory and immunomodulatory capabilities. Research data showed that the levels of key pro-inflammatory cytokines in the serum of newborn piglets in the Macleaya Cordata Extract group were significantly reduced. Simultaneously, at the intestinal mucosal level, Macleaya Cordata Extract significantly upregulated the mRNA expression levels of anti-inflammatory cytokines transforming growth factor-β and interleukin in the ileal mucosa, and significantly downregulated the mRNA expression levels of pro-inflammatory factors IL-33, TNF-α, and IFN-γ.
Source:https://www.sciencedirect.com
Furthermore, the study also observed the regulation of the expression of anti-inflammatory proteins such as REG3γ. This series of findings, from the molecular, cellular, to whole-animal levels, systematically reveals the mechanism by which Macleaya Cordata Extract alleviates inflammation and enhances immune function by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors.
Macleaya Cordata Extract Anti-tumor
Two active components of macleaya cordata plume poppy have the ability to induce the formation of G-quadruplex structures in human telomere DNA, thereby inhibiting telomerase activity and inhibiting tumor cell proliferation.
Reference:https://www.mdpi.com/2076-2615/12/17/2197
https://www.mdpi.com/2306-7381/12/12/1206
https://www.sciencedirect.com/science/article/abs/pii/S0378113524001123
Active effect of Macleaya Cordata Extract
Macleaya Cordata Extract Feed replacement antibody
The main active ingredients of Macleaya Cordata Extract are sanguinarine and chelerythrine, which have strong anti-inflammatory activity. In animals, by inhibiting the outbreak of inflammation, improving intestinal health, and then improving animal growth performance, that is, "anti-inflammation, intestinal regulation, promoting the perfect feed-replacing mechanism for 'growth'.
Macleaya Cordata Extract Protein booster
Macleaya Cordata Extract MCE can inhibit the activity of amino acid decarboxylase and monoamine oxidase, reduce the degradation of amino acids in the intestine, and maintain the integrity of the animal intestine through "anti-inflammation and intestinal adjustment", thereby improving the digestion and absorption efficiency of protein and other nutrients in the feed.
Macleaya Cordata Extract Efficient growth
Through anti-inflammatory and intestine-regulating effects, macleaya cordata plume poppy Extract can reduce animal intestinal inflammation, reduce ineffective consumption of nutrients, and promote body anabolism; maintain intestinal integrity, optimize intestinal microbial flora, improve nutrient utilization efficiency, and promote muscle tissue nutrient deposition.
Macleaya Cordata Extract uses in animals
- As a feed additive, plume poppy macleaya cordata extract is used in pigs, poultry (chickens, ducks, etc.), ruminants and aquaculture.
- It is mainly used to support animal intestinal health and assist in improving growth performance.
- In some countries and regions, it can be used to respond to regulatory requirements to reduce the use of feed antibiotics (AGP).
- It can also be used as veterinary drug raw materials for oral preparations to prevent and treat respiratory diseases of livestock and poultry (such as swine panting disease and chicken cough and runny nose), shortening the recovery period.
- And it can be used as a biological pesticide to effectively kill pests such as mites, snails, maggots, aphids, etc.
macleaya cordata plume poppy Recommended use:
- Applicable animals: pigs, poultry, ruminants, aquatic animals, etc.
- Addition stage: It can be based on your product positioning instructions, such as: use throughout the process, or specific stages such as nursery period and fattening period.
- Recommended addition amount: Mixed with daily diet (recommended addition amount 0.1%-0.5%) to improve the weight gain rate of meat poultry and the egg quality of laying poultry. The actual amount you add should be determined based on the animal species, growth stage, feeding goals and regulatory requirements.
Where to buy Macleaya Cordata Extract?
Looking for bulk Macleaya Cordata Extract for your feed additive projects?
KINTAIBIO® Feeding manufactures and supplies pure, 100% natural Alkaloid extract and Sanguinarine powder from Macleaya Cordata. We specialize in providing high-quality, standardized Macleaya Cordata Extract products. All product claims are supported by verifiable scientific data and experimental results. We offer necessary product technical documentation (such as COA, MSDS, application guidelines) and technical support. For more information on product specifications, application solutions, test data, or to request samples, please contact Kintaibio's sales department at sales@kintaibio.com.
KINTAIBIO® macleaya cordata extract for sale and Product Features:
- Clear ingredients and stable content: The core active ingredients (sanguinarine, chelerythrine) are clear, and the content is standardized to ensure batch-to-batch consistency.
- Technology leadership: Master a variety of advanced extraction technologies, and continuously optimize the process to ensure high product activity and batch stability.
- Natural plant source: Extracted from the natural plant macleaya cordata plume poppy, it has become an ideal choice for replacing antibiotic feed additives and green pesticides.
- Regulatory compliance: The product complies with the relevant announcements of the Ministry of Agriculture and Rural Affairs, and EU Feed Additives Regulations.
- Safety: Used at the recommended dose, it has been evaluated by EFSA for safety. Metabolic studies have shown that it has a low risk of residues in animals. The Macleaya cordata total alkaloids extract we produce is completely consistent with the quality standards of plume poppy macleaya cordata Extract registered by the US EPA.
★If you want to get high-quality Macleaya cordata Extract Powder, please feel free to contact us at sales@kintaibio.com or provide feedback on the next page.
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