Glycyrrhiza Uralensis Extract

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of glycyrrhiza uralensis extract in China. Please feel free to wholesale high quality glycyrrhiza uralensis extract for sale here from our factory. For price consultation, contact us.

KINTAI is committed to becoming your best supplier of glycyrrhiza uralensis extract,which is an ingredient with medicinal value extracted from licorice.It generally includes: glycyrrhizin, glycyrrhizic acid, glycyrrhizin, glycyrrhizic flavonoids, posttential sandalwood extract, oleoresin, quercetin, etc. It is yellow to brownish yellow powder.

It has the effects of tonifying spleen and qi, clearing heat and detoxification, eliminating phlegm and cough, relieving pain slowly and harmonizing various medicines. It is used to treat spleen and stomach weakness, fatigue, palpitation and shortness of breath, cough and phlegm, abdominal pain, limb contracture and other diseases.

Glycyrrhiza uralensis Fisch

Glycyrrhiza uralensis roots

Glycyrrhiza uralensis  slices

Glycyrrhiza uralensis extract 

 

Distribution area: China, Afghanistan, Kazakhstan, Kyrgyzstan, Pakistan, Tajikistan, Mongolia and Siberia of Russia; In China, it is distributed in northeast, north and northwest provinces and regions as well as Shandong. It often grows in dry sandy land, river bank sandy land, hillside grassland and saline soil.

Morphological characteristics: Glycyrrhiza uralensis Fisch. is a leguminous and licorice plant. Perennial herb, roots and rhizomes thick, 1-3 cm in diameter. It tastes sweet. Stems erect, much branched, 30-120 cm high. Leaves 5-20 cm long, stipules triangular lanceolate. Racemes axillary, with many flowers, total pedicels shorter than leaves, densely covered with brown scaly glandular spots and pubescence; Bracts oblong lanceolate, 3-4 mm long; Calyx campanulate, 7-14 mm long, densely covered with yellow glandular spots and pubescence; Corolla purple, white or yellow; Ovary densely prickly hairy glands. The pod is curved like a sickle or a ring. Seeds 3-11, dark green, round or reniform, ca. 3 mm. The flowering period is from June to August, and the fruit period is from July to October.

Medicinal value: roots and rhizomes are used for medicine. In addition to the effects of tonifying the spleen and Qi, moistening the lung and relieving cough, clearing away heat and toxic substances, and harmonizing various medicines, licorice is also used for sore throat, spleen and stomach deficiency, peptic ulcer, poisoning and other symptoms.

The active ingredients are glycyrrhizin, glycyrrhizic acid, glycyrrhizin, licorice flavonoids, bistanol, formononetin, quercetin, etc.

Security Statement: (Europe) 24/25

NONH for all modes of transport

Customs code: 2932999099

Figour1.HPLC-UV chromatogram of G. uralensis (Tohoku licorice) EtOAc extract at 280 nm a−c

.

Each component of the HPLC profile was identified by comparing its retention time, UV and MS spectra (data not shown) with those isolated.

The elution order of the identified components was as follows: demethylated homopulp (10,tR 38.6 min), 7-O-methylbutanone (3, tR 41.2 min), glycyrrhizin (12, tR 46.0 min), glycyrrhizin benzofuran (16, tR 46.6 min), glycerol (18, tR 52.9 minutes), glycylarylcoumarin (19, tR 68.0 minutes), glycyrrhizin (9, tR 73.2 minutes), glycerotriose (20, tR79.4 minutes), glycyrrhizin coumarin (21, tR85.9 minutes), liquorice ketone (22, tR 91.8 minutes), new glycyrrhizinose benzofuran (14, tR 98.1 minutes), licorice isoflavone B (15, tR102.4 min), gliasperin D (23, tR107.4 min), gancaonin G (24, tR112.1 min), gliasperin C (13, tR121.0 min), 8-(γ,γ-dimethylallyl)-wighteone (17, tR 141.1 min), licoricidin (2, tR147.9 min), 4'-O-methylglycybenzofuran (8, tR 156.1 min), Glyasperin J (7, tR 164.5 min), Glycyrrhizin I (1, tR 176.1 minutes), 6,8-diprenol (25, tR 191.3 minutes), glycyrrhizin (11, tR 202.9 minutes), 3'-(γ,γ-dimethylallyl)-kievitone (5, tR 213 .5 min), glycasperin J trimethylether (4, tR 222.8 min) and isoangulone A (6, tR 233.2 min).

Benefits

1. Antioxidant characteristics and mechanism
Glycyrrhiza Uralensis Extract has a significant anti-oxidant effect Studies have shown that ethanolic liquorice root extract has a good scavenging effect on DPPH· and OH· free radicals and superoxide anions. The main component of licorice water extract is glycyrrhizic acid, which can scavenge superoxide anion free radicals and hydroxyl free radicals, inhibit lipid peroxidation, and have anti-aging effects. He Jianrong found that glycyrrhetinic acid has a strong scavenging effect on free radicals of OH· and superoxide anions, and the scavenging ability has a significant correlation with the concentration.

2. The effect on the respiratory system
Licorice and its extracts have antitussive, expectorant, asthmatic, lung protective and pathogenic anti-respiratory effects. Glycyrrhizic acid, glycyrrhetinic acid and licorice flavonoids are the active ingredients of licorice with pharmacological effects on the system respiratory.

3. Effects on the immune system
Licorice and its active ingredients can improve the phagocytic function of phagocytes, regulate the number and function of lymphocytes, inhibit the formation of IgE antibodies, anti-inflammatory mediators and pro-inflammatory cytokines, and have anti-inflammatory pharmacological activities. inflammatory and anti-allergic. Licorice flavonoids (isoliquiritigenin, isoliquiritin, liquiritigenin, licorice chalcone A, glabridin, glycyrrhizin, etc.), glycyrrhizic polysaccharides and glycyrrhizic acid are its active ingredients for anti-inflammatory and anti-allergic inflammation.

4. Antispasmodic effect on gastrointestinal smooth muscle
Licorice decoction, liquid licorice extract, liquiritigenin, isoliquiritigenin, etc. all have obvious antispasmodic effects on the body. Flavonoids such as FM100 and isoliquiritigenin have some degree of inhibitory effect on the intestines of isolated animals at a concentration of 10-5 and can relieve intestinal spasms caused by acetylcholine, barium chloride and l histamine, while glycyrrhizin, glycyrrhetinic acid has no obvious inhibitory effect. on smooth muscle.

5. Mineralocorticoid-like effects
Licorice extract, glycyrrhizin and glycyrrhetinic acid all have the effect of promoting sodium and water retention in humans and animals. It has a good curative effect on mild Addison's disease, but is ineffective even in high doses for severe Addison's disease which does not secrete corticosteroids. Therefore, only in the presence of aldosterone and hydrocortisone, licorice can produce corticosteroid-like effects. Small doses of glycyrrhizin can atrophy the thymus and increase the weight of the adrenal glands in rats, producing a cortisone-like effect of the glucocorticoid. When the dose is large, the hormone-like effect is not evident and only a mineralocorticoid-like effect is shown.

6. Detox
Licorice extract and glycyrrhizin have some detoxifying ability for certain drug poisoning, food poisoning and metabolite poisoning in vivo. Glycyrrhizin is an effective ingredient for detoxification. The mechanism of detoxification is that glycyrrhizin has a certain adsorption effect on poisons, and its hydrolyzed product glucuronic acid can combine with poisons. The ability of detoxification is the result of various comprehensive factors. The results of the experiment revealed that licorice extract and glycyrrhizin had a significant detoxifying effect on strychnine, urethane, cocaine, benzene, arsenic, mercuric chloride and other toxicities; at the same time, it can also alleviate the lethal effects of diphtheria toxin and tetanus toxin. 

Application

★ Cosmetics: 

① whitening effect 

② sunscreen agent 

③ cosmetic additive. It can resist inflammation, prevent hands and feet chaps and frostbite, and can be used in cosmetics such as cream.

★ Food: licorice extract is an ideal antioxidant and preservative in the food industry, and can also be used as food additives, as condiments, sweeteners, as well as tobacco and cigars. It is also used as the base material for the preparation of essence such as chocolate, beer, vanilla and liqueur. This product is non-toxic and is a traditional antidote and sweetener in China.

★ Medicine: invigorate spleen and qi, clear heat and detoxify, dispel phlegm and cough, and relieve pain slowly.

 

 

★If you want to get high-quality Glycyrrhiza Uralensis Extract, please feel free to contact us at cheney@kintaibio.com or feedback on the next page.

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