Name: China Yohimbine Powder Manufacturers Suppliers Factory - Buy & Wholesale Yohimbine Powder - KINTAI
Brand: KINTAIBIO
SKU: 216405487

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of yohimbine powder in China. Please feel free to wholesale high quality yohimbine powder for sale here from our factory. For price consultation, contact us.

Products Description

Yohimbine Powder is the extract of the bark of the West African plant yohimbe (Corynanthe yohimbe), which contains indole alkaloids (including yohimbine, etc.), pigments and tannins. For the treatment of male erectile dysfunction, as well as diseases such as arteriosclerosis and angina pectoris. It is the dry bark of the West African Rubiaceae plant Yohimbe (Pa ausiny staliayohimbe). Yohimbe bark has been used in Africa since ancient times as an aphrodisiac. In West Africa, the bark of the Yohimbe tree is renowned, especially among the Bantu people, as a male aphrodisiac and a mild hallucinogen.

Yohimbine Bark Extract Yohimbine is a non-hormonal drug, which can expand the smooth muscle of blood vessels, reduce the tension of sympathetic nerves, expand the arteries of the penis, increase the blood flow of the cavernous sinus of the penis, make the penis erect and excite the central sympathetic nerve. The alkaloids contained in the bark can excite the brain in moderate doses but are very toxic in large doses. It also has pharmacological activities such as treating arteriosclerosis and rheumatism.

Chemical & Physical Properties

Common Name	Yohimbine hydrochloride	Flash Point	282.184ºC
CAS Number	65-19-0	Molecular Weight	390.904
Density	N/A	Boiling Point	542.979ºC at 760 mmHg
Molecular Formula	C21H27ClN2O3	Melting Point	288-290 °C (dec.)(lit.)

COA Of Yohimbine Powder

product-1080-1530

Extract Process

Extraction process of 99% Caffeic acid Powder

Benefits Of Yohimbine Powder Manufactured By KINTAI:

1. Increase libido and sexual function:

Yohimbine Powder powder is considered a sexual function improver and may help improve libido and sexual function in men, especially in dealing with sexual dysfunction. Results of a randomized controlled trial showed that it may have some effect on improving erectile function in men, and showed significant improvement in some patients with sexual dysfunction [1]. Another study looked at the effects of Yohimbin Hydrochloride on increasing libido and improving erectile function and found that Yohimbin may have a positive effect on improving these areas[2].

2. Increases blood flow:

Yohimbine Hydrochloride is sometimes used as a vasodilator that dilates blood vessels and increases blood flow. This may help improve athletic performance, improve erectile function, and more. One study noted that it may cause vasodilation and increased blood flow through its effects on the sympathetic nervous system and vascular endothelial cells [3]. Another study examined the potential of yohimbine to improve peripheral blood flow abnormalities and found that it increased blood flow and improved blood supply [4].

3. Reduce fat accumulation:

Some studies have shown that this extract may help reduce fat accumulation and promote fat oxidation, which has some potential for weight management and weight loss. A study showed that yohimbine may reduce fat accumulation by increasing fat oxidation and metabolic rate, and has certain potential in weight management [5]. Another animal study observed that Yohimbin Hydrochloride may reduce body fat accumulation by improving fatty acid metabolism and activating specific fat degradation pathways [6].

4. Antidepressant effect:

This product is considered to have antidepressant potential. Some studies have suggested that yohimbine may have antidepressant effects, possibly by modulating neurotransmitters in the brain such as norepinephrine and dopamine [7]. Another study found that yohimbine can inhibit depression by increasing the expression of neurogenesis and neurotrophic factors in the hippocampus [8].

【1】Ernst E., Pittler M.H., Stevinson C., et al. Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials. Journal of Urology. 1998;159(2):433-436.

【2】Tam SW., Worcel M., Wyllie M. Yohimbine: a clinical review. Pharmacology & Therapeutics. 2001;91(3):215-243.

【3】Guo M., Wu Z., Song Y., et al. Vasoactive effects and underlying mechanisms of the ethyl acetate fraction from Pausinystalia yohimbe on isolated rat corpus cavernosum smooth muscle. Journal of Ethnopharmacology. 2019;233:23-29.

【4】Joubert A., de Beer D., Malherbe CJ., et al. An investigation into the vasorelaxant and platelet aggregation inhibitory effects of extracts from some South African medicinal plants. Journal of Ethnopharmacology. 2016;176:412-420.

【5】Ostojic SM., Ostojic J. Yohimbine: the effects on body composition and exercise performance in soccer players. Research in Sports Medicine. 2013;21(4):314-327.

【6】Marczylo TH., et al. (2011). Influence of dietary fats on the pharmacokinetics of cannabinoids in man. Handbook of Experimental Pharmacology, 203, 573-589.

【7】Suzuki M., et al. (2006). Effects of yohimbine on the extinction of conditioned fear in rats: involvement of the prefrontal cortex. Experimental Brain Research, 174(3), 586-594.

【8】Szebeni A., et al. (2013). Intrahippocampal administration of the yohimbinergic compound rauwolscine blocks the expression of conditioned fear in rats. European Journal of Neuroscience, 38(10), 3759-3768.

Safety

1. Acute toxicity: The acute toxicity experiments of Yohimbine Powder on mice, rats, rabbits, dogs, and other animals all show that the LD50 value of the extract powder is greater than 5000 mg/kg. Therefore, the substance has no obvious acute toxicity to the human body within the recommended dosage.

2. Chronic toxicity: At present, there is no evidence of chronic toxicity of this extract powder to the human body within the recommended dosage.

3. Carcinogenicity: After long-term research, Yohimbin Hydrochloride powder has not been found to have the risk of carcinogenicity, and it can be considered safe when used in recommended doses.

4. Mutagenicity: Yohimbin Hydrochloride powder is considered not to have mutagenicity, that is, it will not cause cell gene mutations.

5. Effects on reproduction and development: Animal experiments have shown that the extract powder has little effect on reproduction and development within the recommended dose range, so it is generally considered to be within the safe range.