Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of 5-htp powder in China. Please feel free to wholesale high quality 5-htp powder for sale here from our factory. For price consultation, contact us.
5-Hydroxytryptophan (5-HTP) powder manufacturer
5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid and a key derivative of tryptophan metabolism. In mammals, 5-HTP is a direct precursor for the synthesis of the key neurotransmitter serotonin (5-HT) and the hormone melatonin (MT). Serotonin regulates mood, cognition, appetite, and sleep, while melatonin governs the body's sleep-wake cycle. Therefore, 5-HTP, as an important dietary supplement ingredient, has a wide range of applications, including improving mood, promoting sleep, alleviating anxiety, and suppressing appetite.
Kintaibio offers 5-HTP powder produced through a biofermentation process with a stable purity of ≥99%. It is a white to off-white fine powder. This product poses no risk of plant allergies, contains very low impurities, and meets high-quality standards, making it an ideal choice for pharmaceutical and high-end dietary supplement formulations. For detailed specifications and test reports, please contact sales@kintaibio.com
Our 5-HTP powder packing details
99%+ 5-HTP powder manufacturer-kintaibio®
Packaging：Cardboard drums (lined with double food-grade plastic bags), or as per customer requirements
KINTAIBIO® 5-HTP Powder TDS
| Product Name | 5-HTP Powder | Chemical Name | 5-Hydroxy-L-tryptophan |
| CAS Number | 56-69-9 | Alias | Oxitriptan, DL-5-HTP |
| Molecular Formula | C11H12N2O3 | Molecular Weight | 220.23 |
| Melting Point | 270 °C (dec.)(lit.) | Solubility | H2O < 10 mg/mL; DMSO 16 mg/mL (72.65 mM) |
| pH | 5.0-7.5 | Optical Rotation 20° | -30.0°-35.0° |
| Appearance | White or off-white powder | Purity |
≥ 99.0% (verified by HPLC)[actual Purity above 99.7%] |
| Density | 0.902 g/mL, 25 °C (lit.) | Related impurities | ≤ 0.3 % Peak X free. |
| Loss on Drying | ≤ 0.5 % | Ash | ≤ 0.3 % |
| Heavy metals |
Pb<0.5ppm As<0.5ppm Hg<0.1ppm cd<0.1ppm |
Pesticide Residue | Complies with USP <561> and EU EC 396/2005 standards |
| Total Plate Count | ≤ 1,000 CFU/g | Yeast & Mold | ≤ 100 CFU/g |
KINTAIBIO® 5-HTP powder Production Process
Our company utilizes genetically engineered microbial strains (such as engineered yeast or E. coli) and core technologies such as directed evolution of enzyme engineering, optimized coenzyme regeneration, and metabolic pathways to produce 5-HTP with over 99% purity and stable, controllable quality.
1. The production process is as follows:
Inoculation of engineered strains → Fermentation in large-scale bioreactors → Metabolite accumulation → Fermentation broth separation → Ultrafiltration purification → Precision chromatography → Crystallization → Drying → Finished product (99%5-HTP+ high purity)
2. detailed Production Process
- Strain screening: Optimized, non-GMO microbial strains are selected.
- Fermentation: Specific nutrients are provided to the microorganisms in a strictly controlled bioreactor, enabling efficient conversion and production of 5-HTP.
- Purification: 5-HTP is isolated and purified from the fermentation broth through a series of advanced separation, filtration, and chromatography techniques.
- Crystallization and drying: High-purity 5-HTP crystals are obtained and then dried at low temperatures to ensure stability.
- Quality Inspection and Packaging: Each batch of product undergoes rigorous quality inspection (CoA) and is packaged in a GMP-compliant environment.
3. Technical Advantages:
- Purity: Our product boasts a purity exceeding 99.7%, far exceeding the 99% purity of standard products on the market. It is Peak X Free, resulting in unparalleled safety.
- Risk-Free: Our product is completely plant-based, eliminating the risk of pesticide residues and plant-derived allergens.
- Sustainability: Our production is unrestricted by season, climate, or location, ensuring a stable year-round supply. Our scale-based approach results in more competitive costs.
Need naturally sourced 5-HTP?
If you require 5-HTP extract derived from Griffonia simplicifolia seeds, we also offer a full range of products, from standardized 15:1(25%5-HTP) extracts to 98% 5-HTP powders. These products retain their natural properties to meet your diverse product needs. For more information on naturally derived 5-HTP, please click here to learn more. https://www.kintai-bio.com/plant-extracts/standardized-extracts/griffonia-seed-extract-powder.html
5-HTP powder Application
* Premium Mood Support Supplements
* Sleep Enhancement Formulas
* Cognitive Health Complex Products
* Pharmaceutical Intermediates
Why choose kintaibio® 5-HTP powder? - where can you purchase 5 htp powder?
Full-range supply, one-stop solution: From natural extracts to ultra-high-purity fermented products, we offer the most comprehensive range of specifications to meet all your formulation needs, from basic to advanced.
Production Technology: We master both advanced natural extraction and bio-fermentation production technologies, providing customers with high-quality products of varying specifications and positioning, helping you flexibly respond to diverse market demands.
Strict Quality Control: We utilize a variety of testing methods, including HPLC and TLC, to ensure the accuracy and consistency of each batch of product.
Stable Supply: Fermentation-based products, in particular, eliminate the fluctuations of agricultural yields, ensuring the long-term security and stability of your supply chain.
Technological Revolution: Our proprietary fermentation technology optimizes the production of 5-HTP, resulting in a product that far surpasses traditional plant-based extracts and has established a dominant position in the market.
Our Quality Commitment: We are not only a GMP-certified 5-HTP producer, but also a driving force behind industry standards. From raw materials to finished product, we implement a rigorous quality control system throughout the entire process, ensuring every indicator meets regulatory requirements in major global markets (including US FDA dietary supplement standards and EU food safety standards), safeguarding the safety and compliance of your products.
FAQ: Can 5-HTP help with weight loss?
Yes, research suggests that 5-HTP may support weight loss, primarily by improving appetite control and reducing overeating.
Animal studies have shown that 5-HTP can increase blood levels of leptin, a hormone that promotes satiety, thereby helping to regulate food intake. This effect is supported by clinical trials in humans. For example, a five-week study involving 19 obese women who took 8 mg per kilogram of body weight of 5-HTP daily - without following any specific diet - resulted in an average weight loss of 5%. Similar outcomes were observed in longer-term studies and in individuals with non-insulin-dependent diabetes.
Overall, evidence indicates that 5-HTP can be effective in reducing appetite and supporting weight management.
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Q: Is 5-HTP a natural product?
A: Yes, 5-HTP is a naturally occurring compound, but the supplements you buy are typically synthesized. Natural Source: 5-HTP is the direct precursor to serotonin. In nature, it is produced from the amino acid tryptophan. A primary natural source is the seeds of the African plant Griffonia simplicifolia. Most 5-HTP supplements on the market are extracted from these seeds. Synthetic Production: While derived from a plant, the extraction and processing result in a concentrated supplement. It is not found in significant amounts in a typical diet. You cannot eat enough foods containing 5-HTP to achieve the same effect as a supplement; it must be processed and concentrated. In short, it is a natural compound, but commercial 5-HTP is a processed botanical extract.
Q: Is 5-HTP good for sleep?
A: Yes, 5-HTP may help improve sleep quality for some people, particularly by reducing the time it takes to fall asleep and increasing dream activity (REM sleep). How it works: 5-HTP boosts the production of serotonin. Serotonin is then converted into melatonin, the key hormone that regulates your sleep-wake cycle. By increasing serotonin levels, 5-HTP indirectly supports the body's natural production of melatonin. Evidence: Studies suggest it can be beneficial for sleep disorders like insomnia, especially when related to low serotonin levels (e.g., in depression or anxiety). However, evidence is not as robust or direct as it is for melatonin itself.
Q: Who should avoid 5-HTP?
A: Several groups of people should avoid or use extreme caution with 5-HTP: People on SSRI/SNRI Antidepressants (e.g., Prozac, Zoloft, Cymbalta): This is the biggest risk. Combining 5-HTP with these medications can lead to serotonin syndrome, a potentially life-threatening condition caused by excessive serotonin activity. People on Parkinson's Medication (Carbidopa/Levodopa): 5-HTP can exacerbate side effects like nausea and hardening of the skin (scleroderma-like symptoms). People Taking Triptan Migraine Medications or Dextromethorphan (cough syrup): These also increase serotonin and raise the risk of serotonin syndrome when combined with 5-HTP. Pregnant or Breastfeeding Women: There is not enough research to confirm its safety for the mother or baby. People with Eosinophilia-Myalgia Syndrome (EMS) history: A past outbreak of this serious condition was linked to a contaminated tryptophan supplement. While modern 5-HTP is considered much safer, those with a history of EMS should avoid it. People Scheduled for Surgery: Because it affects serotonin, it could interfere with sedatives and other medications used during surgery. Stop using it at least two weeks before a scheduled procedure. Always consult a doctor before starting 5-HTP, especially if you have a medical condition or are taking any other medications.
Disclaimer: This information is for educational purposes only and is not medical advice. Always consult with a healthcare professional before starting any new supplement regimen.
If you need to purchase Kintaibio's 5-HTP powder for your business purposes, please contact our sales team at sales@kintaibio.com or provide your requirements on the next page.
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