raspberry ketone powder

Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of raspberry ketone powder in China. Please feel free to wholesale high quality raspberry ketone powder for sale here from our factory. For price consultation, contact us.

raspberry ketone powder is a natural organic compound with the chemical name 4-(4-hydroxyphenyl)butanone. It was originally obtained from raspberries (Rubus idaeus) and is mainly found in the rind of this fruit. raspberry ketone can also be obtained by chemical synthesis.

raspberry ketone has a special aroma and is widely used in food, fragrances, and cosmetics. In addition, raspberry ketone powder are considered to have a variety of biological activities and pharmacological effects. Studies have shown that raspberry ketone has the effect of promoting lipolysis and metabolism, which means that it can help people manage their weight and reduce the incidence of obesity. Specifically, raspberry ketone achieves this effect by activating a protein called fatty acid transporter protein (FAT/CD36) in adipocytes. activation of FAT/CD36 increases the intracellular metabolism and oxidation of fatty acids, thereby promoting lipolysis and reducing fat accumulation.

 

 

2.Product quality specification & standard

 

Product name	Raspberry extract
Extraction Solvent	Ethanol
Appearance	Brown powder
Solubility	Insoluble in water and petrolatum, soluble in ethanol, ether and volatile oil.
Identification	HPLC
Heavy metals	NMT 20 PPM
Loss On Drying	NMT 5.0%
Powder size	80Mesh, NLT90%
Assay	Min. 95.0%
Residual Solvents
- Ethanol	NMT 5000 PPM
Microbiological Quality (Total viable aerobic count)
- Bacteria, CFU/g, not more than	NMT 10³
- Moulds and yeasts, CFU/g, not more than	NMT 10²
- E.coli, Salmonella, S. aureus, CFU/g	Absence
Storage	In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China
Shelf life	3 years

 

3.What can KINTAI do?

 

 

 

1) Anti-tumor effect

The raspberry water extract was dried and dissolved in tumor cell culture medium (DMEM) to obtain raspberry pulp with different concentrations. The inhibitory effect of raspberry pulp on the proliferation of human primary liver cancer was detected by the MTT method and morphology. The results showed that various concentrations of raspberry pulp had inhibitory effects on the proliferation of human primary liver cancer cells, showing a dependence on drug concentration and action time. Raspberry water extract also has an inhibitory effect on matrix metalloproteinase (MM-13), and its inhibitory effect is obviously proportional to the concentration.

2) Lower blood sugar and blood fat

The alloxan-induced hyperglycemia model was used to continuously administer 0.40, 0.80, and 1.20 g/kg water extracts to observe its effects on fasting blood glucose, glucose tolerance after glucose administration, and the area under the curve. At the same time, a model control group was set up, and the results showed that raspberry water extract had an obvious hypoglycemic effect.

3) Antioxidant effect

Raspberry glycoprotein crude extract can significantly enhance the activities of catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) in mouse serum, liver, and brain tissue, has a certain reducing ability, and can effectively scavenge hydroxyl radicals (OH), superoxide anion radicals (O2-) and DPPH free radicals, and have obvious antioxidant effects.

Raspberry crude polysaccharides and purified polysaccharides have a strong ability to scavenge oxygen-free radicals. Raspberry ethanol extract, ethyl acetate fraction and n-butanol fraction also had significant scavenging capacity for DPPH free radicals. The half-inhibitory concentrations (IC50) were 17.9, 3.4, and 4.0 μg/mL, respectively, and the kaempferol, vanillic acid, and lindenol isolated from them had strong scavenging ability. The aqueous extract of raspberry protects rat primary hepatocytes against test-butyl hydroperoxide (t-BHP)-induced oxidative stress, significantly limiting the reduction in cell viability.

4) Antithrombotic effect

The 70% ethanol extract of raspberry leaves has a significant antithrombotic effect in vivo and in vitro tests, and the isolated kaempferol, quercetin, and lindenin can significantly delay the plasma recalcification time (PRT) in the blood.

5) Anti-aging effect

6) Anti-inflammatory effect

Matrix metalloproteinases play important roles in normal physiological and pathological processes, and they are involved in normal skin functions such as aging, healing, development, and inflammatory responses of the skin. Tumor necrosis factor (TNF-α) induces the production of metal matrix proteases (MMP-1 and MMP-9), and raspberry can inhibit the activity of MMP-1.

7) The effect of removing chloasma

According to the color and area of the subjects' chloasma, 108 subjects were randomly divided into a trial group and a control group, with 54 cases in each group, all of whom were women. The test group took raspberry extract for 30 days, and the control group took blank control. Observe the changes in the size and color of chloasma on the face of the subjects. The results show that raspberry extract has the effect of removing chloasma.

Preparation of raspberry extract from raspberries

1) Take raspberry medicinal material, remove impurities, wash with water, dry, crush, and pass through an 800-mesh sieve to obtain raspberry powder;

2) Add raspberry powder to 70% ethanol aqueous solution at a volume percentage concentration of 20mL/g liquid-to-material ratio, stir evenly, perform ultrasonic extraction at 25kHz, 450W, and 45°C for 45min, and extract twice;

3) filtering the alcohol extraction mixture in step S2 to obtain a raspberry alcohol extract, and then concentrating to obtain a raspberry concentrate whose volume is 1/8-1/6 of the volume of the raspberry alcohol extract;

4) Freeze-dry the raspberry concentrate at -30～-40°C for 25 minutes, grind it into powder, and pass it through a 200-mesh sieve to obtain the raspberry extract.

After testing, the content of raspberry ketone powder in the raspberry extract prepared above is 1.25 wt%.

If you want to purchase high-quality raspberry ketone powder, please feel free to contact us at sales@kintaibio.com or feedback on the next page.

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