Xi'an Kintai Biotech Inc is one of the most experienced manufacturers and suppliers of pure kojic acid powder in China. Please feel free to wholesale high quality pure kojic acid powder for sale here from our factory. For price consultation, contact us.
Product Description
pure kojic acid powder is a melanin-specific inhibitor. After entering skin cells, it can complex with copper ions in the cells, change the three-dimensional structure of tyrosinase, prevent the activation of tyrosinase, and thus inhibit the formation of melanin. It exists in the culture medium of Aspergillus (Aspergillus). It can be obtained by aerobic fermentation of Aspergillus oryzae.

Physicochemical properties
| CAS Number | 501-30-4 | Molecular Weight | 142.11 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 401.7±45.0 °C at 760 mmHg |
| Molecular Formula | C6H6O4 | Melting Point | 152-155 °C(lit.) |
| Common Name | pure kojic acid powder | Flash Point | 179.9±22.2 °C |
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Product quality specification & standard
|
Product name |
pure kojic acid powder |
|
Appearance |
White powder |
|
Solubility |
easily soluble in water, alcohol, and acetone, slightly soluble in ether, ethyl acetate, chloroform, and pyridine, and insoluble in most other solvents. |
|
Identification |
HPLC |
|
Ash |
NMT 0.5% |
|
Heavy metals |
NMT 20 PPM |
|
Loss On Drying |
NMT 5.0% |
|
Powder size |
80Mesh, NLT90% |
|
Assay |
Min. 95.0% |
|
Residual Solvents |
|
|
- Ethanol |
NMT 5000 PPM |
|
Microbiological Quality (Total viable aerobic count) |
|
|
- Bacteria, CFU/g, not more than |
NMT 103 |
|
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
|
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
|
Storage |
In a Tight, Light-resistant, and Dry Place. Avoid Direct Sunshine. Country of Origin: China |
|
Shelf life |
3 years |
Benefits
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has antioxidant and antibacterial properties, so it helps aid in food preservation. Helps maintain the freshness of food for a long time. Some dermatologists use ointments containing "5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- " for acne because it is effective at killing the bacteria that cause acne breakouts.
In addition, the effects of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- on the skin are:
- whitening
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- at a concentration of 20 μg/ml can inhibit 70-80% of the activity of various tyrosinases (also known as polyphenol oxidase PPO). Generally, 0.5-2.0% in cosmetics can inhibit melanin, reaching a Whitening effect.

- Freckle removal
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can inhibit the synthesis of tyrosinase and the formation of skin melanin, which is relatively safe and has no sequelae. Therefore, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has been formulated into skin care products such as essence, mask, and lotion by many brands, which can effectively treat freckles, chloasma, and age spots.

Application
1. Applied in the field of cosmetics. In human skin, under the catalysis of tyrosinase, tyrosine undergoes complex oxidation and polymerization with oxygen free radicals and finally synthesizes melanin. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of skin melanin, and pure kojic acid powder is safe and non-toxic, and will not cause sequelae of leukoplakia. Therefore, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has been formulated into lotion, facial masks, lotion, and skin creams to make Become a high-end whitening cosmetics that can effectively treat freckles, age spots, pigmentation, acne, etc. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- at a concentration of 20UG/ML can inhibit the activity of 70-80% of various tyrosinases (or polyphenol oxidase PPO), and the general addition amount in cosmetics is 0.5-2.0.

2. Food processing field. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can be used as a food additive to preserve freshness, preserve antiseptic, and resist oxidation. Experiments have proved that 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can inhibit the transformation of sodium nitrite in bacon into carcinogenic nitrosamines, and the addition of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- to food will not affect the taste, aroma, and texture of food; 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- is also a source of maltol and ethyl maltol In food processing, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has a wide range of applications.
3. The field of medicine. Because 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has no mutagenic effect on eukaryotic cells and can eliminate free radicals in the human body, enhance white blood cell motility, etc., which is beneficial to human health, so 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- has been used as a raw material for cephalosporin antibiotics, and the finished medicine produced is used to treat For headache, toothache and local inflammation and other diseases, the analgesic and anti-inflammatory effects are very ideal.
4. In the field of agriculture. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can be used to produce biological pesticides. Biological micro-fertilizer (dark red liquid) made by adding 0.5-1.0 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy-, whether it is sprayed as a foliar fertilizer at a low concentration, or made into a growth-increasing agent for root application, this crop production accelerator is very effective for grain and vegetables All have obvious yield-increasing effects.
5. In other fields. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- can also be used as an iron analysis reagent, film spot remover, etc.
Safety
1. The current evaluation of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- by the Cosmetic Raw Materials Evaluation Committee (CIR) in the United States concludes that under certain conditions of use, the maximum allowable concentration of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- (1.0% by a mass fraction) is safe.
2. SCCS gives the maximum safe concentration of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- as 0.7% when used as a cosmetic whitening agent.
Precautions while using 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy-
1. Choose a regular 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- manufacturer
Because the compliant and safe 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- addition should be less than 2%, generally between 0.5-2%. The safety of 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- products exceeding this content cannot be guaranteed.
2. Before using 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- , a certain tolerance period needs to be established.
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- is unstable to light, heat, and metal ions, so do not add it at high temperatures when formulating, and control the content of iron and other metal ions in the system.
3. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- should be protected from light.
In a strong light environment, there may be inactivation, which will instead cause melanin to increase. After use, remember to do sunscreen! Therefore, like other acidic products, such as salicylic acid, fruit acid, and alcohol A, it should be used at night as much as possible. Try to avoid the overlapping use of multiple acids, which may damage the skin barrier, and the strong medicine is too fierce, and it will also cause damage to the skin!
4. 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 5-Hydroxy- is unstable to light, heat, and metal ions. Do not add it at high temperature when formulating, and control the content of iron and other metal ions in the system.
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